Navigation Links
Medivation Announces Positive New Efficacy Data From Phase 1-2 Trial of MDV3100 in Advanced Prostate Cancer Patients
Date:6/2/2009

-- Findings Presented at American Society of Clinical Oncology 2009 Annual Meeting and Included in Best of ASCO(R) Educational Program --

SAN FRANCISCO, June 2 /PRNewswire-FirstCall/ -- Medivation, Inc. (Nasdaq: MDVN) today announced the presentation of new clinical results from a Phase 1-2 trial evaluating MDV3100, a next-generation androgen receptor antagonist, in castration-resistant prostate cancer (CRPC) patients. The new findings, which include data from all 140 enrolled patients, confirm previously reported results that MDV3100 consistently demonstrated anti-tumor activity in both chemotherapy-naive and post-chemotherapy CRPC patients across dose levels and endpoints, as evaluated by reductions in prostate specific antigen (PSA) levels, radiographic findings and circulating tumor cell (CTC) counts.

New findings include the median time to PSA progression, which was 6.1 months for post-chemotherapy patients, with the median time not yet reached for chemotherapy-naive patients. In addition, the median time to radiographic progression was 6.6 months for post-chemotherapy patients, with the median time not yet reached for chemotherapy-naive patients.

"These new clinical data in the post-chemotherapy setting are encouraging because these patients have a poor prognosis, surviving on average a year or less -- with no approved treatment options," said Howard Scher, M.D., principal investigator of the trial and chief of the Genitourinary Oncology Service and the D. Wayne Calloway Chair in Urologic Oncology at Memorial Sloan-Kettering Cancer Center in New York. "These findings suggest that MDV3100, with its unique mechanism of action, provides beneficial clinical effects in contrast to those achieved with first-generation androgen receptor antagonists."

In vitro data recently published in Science'/>"/>

SOURCE Medivation, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Pfizer and Medivation Initiate Phase 3 Trial of Dimebon Added to Donepezil in Patients with Alzheimers Disease
2. Medivation Completes Enrollment of Phase 1-2 Trial of MDV3100 in Castration-Resistant Prostate Cancer Patients
3. Medivation Presents Positive New Data on Dimebons Long-Term Efficacy and Novel Mechanism of Action at the International Conference on Alzheimers Disease
4. Medivation Announces Publication in The Lancet of Dimebon Pivotal Trial Results in Alzheimers Disease
5. Medivation Announces Positive Top-Line Results From Phase 2 Dimebon Study in Huntingtons Disease
6. Medivation to Host Conference Call at 5 p.m. EDT Monday to Discuss Top-Line Phase 2 Study Results in Huntingtons Disease
7. Medivation Initiates Second Pivotal Phase 3 Trial of Dimebon(TM) in Patients With Alzheimers Disease
8. Medivation Announces Presentation of Positive MDV3100 Clinical Data in Castration-Resistant Prostate Cancer Patients at 44th ASCO Annual Meeting
9. Medivation Announces Presentation of MDV3100 Clinical Data in Patients With Castration-Resistant Prostate Cancer at 44th American Society of Clinical Oncology Annual Meeting
10. Medivations Dimebon(TM) Significantly Improved Thinking and Memory in Alzheimers Disease Patients Over One Year
11. Medivations Dimebon(TM) Significantly Improved Daily Function in Alzheimers Disease Patients, Resulting in Reduced Need for Caregiver Assistance
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... DUBLIN , Jan. 23, 2015  Immune Therapeutics, Inc. ... Biotechnology, Inc. for the compounding, packaging and distributing of its ... the United States . ... of compounding naltrexone tablets in various strengths for individual patients ...
(Date:1/23/2015)... 23, 2015  iMD Companies, Inc. (ICBU) has repositioned itself as ... and grab a foothold in the hydroponic, hemp and medical ... a presence in the sector, and recently partnering with the ... hemp and medical marijuana, iMD is committing to bring its ...
(Date:1/23/2015)... 23, 2015  Mallinckrodt plc (NYSE: MNK ) ... a share repurchase program. The open-ended authorization permits the ... plc ordinary shares. "Funding additional initiatives ... as we continue to pursue a range of focused ...
Breaking Medicine Technology:Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 2Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 3Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 4iMD Companies Poised to Make Impact in Multi-Billion Dollar Medical Marijuana Sector With Recent Investments and Strategic Partnerships 2Mallinckrodt plc Announces Share Repurchase Program 2Mallinckrodt plc Announces Share Repurchase Program 3Mallinckrodt plc Announces Share Repurchase Program 4
... 2012 Star Scientific, Inc. (NASDAQ: CIGX ... Inc., announces that it has received important new research ... Sarasota, Florida. The Institute has completed a successful animal ... anatabine (patent pending), in an animal model of multiple ...
... PDII ) today announced that it will release its ... after the market close and host a conference call on ... the results.Access information:Date: , Tuesday, May 15, 2012Time:  , ... and Canada) or (706) 643-1203Conference ID number: , 72367450Live web ...
Cached Medicine Technology:Roskamp Institute Reports Beneficial Effects of Nutritional Supplementation with Anatabine in an Animal Model of Multiple Sclerosis 2Roskamp Institute Reports Beneficial Effects of Nutritional Supplementation with Anatabine in an Animal Model of Multiple Sclerosis 3Roskamp Institute Reports Beneficial Effects of Nutritional Supplementation with Anatabine in an Animal Model of Multiple Sclerosis 4
(Date:1/22/2015)... January 23, 2015 Recently, Weddingshe.com has added ... and has announced its highest annual revenues in the past ... its popular glamorous wedding dresses. , According to the sales ... wedding dress promotions for them in 2015. This point can ...
(Date:1/22/2015)... January 22, 2015 Payday lending practices ... communities and cause financial distress to the states that ... at Howard University’s Center on Race and Wealth. , ... economic activity, payday loans at the same time substantially ...
(Date:1/22/2015)... 22, 2015 JJsHouse.com is a famous dress ... the business announces its latest collection of wedding dresses ... most important issue is the wedding dress on your big ... a woman’s life. Every bride wants to find the most ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Step into ... at the Science Museum of Virginia. Wicked Plants, the ... Wicked Plants unearths 75 poisonous, carnivorous and diabolical plants ... each room to uncover the biochemical, physical and neurological ...
(Date:12/26/2014)... It is said that nothing makes a ... the famous wedding dress supplier, shows its new selection ... gown promotion. , UWDress.com’s navy cocktail gowns are the ... in high fashion styles. Simple dresses in bright neon colors ...
Breaking Medicine News(10 mins):Health News:Weddingshe Announces A Special Offer On Its Popular Glamorous Wedding Dresses 2Health News:Howard University Spotlights the Economic Impact of Payday Lending in Southern States 2Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2Health News:Wicked Plants are taking over the Science Museum of Virginia 2Health News:UWDress.com Shows Its New Navy Cocktail Dresses For 2015 2
... a new technology that relies on thousands of synthetic molecules ... method for detecting Alzheimer,s disease with a simple blood test. ... important diseases, according to the report in the January 7th ... publication. "If this works in Alzheimer,s disease, it suggests ...
... on reactive oxygen species (ROS) ions or very small ... they damage cell structure and their potential link to stroke, ... Eli and Edythe Broad Center of Regenerative Medicine and Stem ... stem cells, the cells that give rise to neurons, maintain ...
... Spartanburg, S.C., USA, 6 January, 2010 Researchers at Wofford ... over 1000 objects, differentiating between names of objects and orders ... in Germany, who had discovered a dog that knew the ... left open as to how far a dog could go, ...
... The use of combined treatments for severe acute ... disease, resulting in shorter hospitalizations and fewer radiological ... in Clinical Gastroenterology and Hepatology , the ... Institute. In a related study, doctors found that ...
... simpler form of testing individuals with risk factors for ... the number of individuals who complete testing and learn ... Approximately 60 million Americans, one-third of the adult ... develop Type 2 diabetes in less than a decade, ...
... the most widely produced fruit in the world and ... a nutrient which could tackle the onset of vascular ... Nutrition & Food Research , reveals that an extracted ... team led by Dr Teruo Kawada, from Kyoto University ...
Cached Medicine News:Health News:A blood test for Alzheimer's disease? 2Health News:A blood test for Alzheimer's disease? 3Health News:Neural stem cells maintain high levels of reactive oxygen species, UCLA study finds 2Health News:Neural stem cells maintain high levels of reactive oxygen species, UCLA study finds 3Health News:Border collie comprehends over 1,000 object names 2Health News:Border collie comprehends over 1,000 object names 3Health News:Less invasive techniques help manage complications of severe pancreatic disease 2Health News:Less invasive techniques help manage complications of severe pancreatic disease 3Health News:Routine blood test may identify people with pre-diabetes, cutting later treatment costs 2Health News:Routine blood test may identify people with pre-diabetes, cutting later treatment costs 3
... Tecan Haemotyper is an automated ... The Tecan Haemotyper combines a ... platform with the DiaMed agglutination ... process DiaMed-ID cards and microplates ...
... people are in need of MRI exams, ... tunnel-type scanners. They have heard of, or ... claustrophobic and noisy tubes of supercon scanners ... What people want is a patient-friendly MRI. ...
Picofluor™ Fluorometer is a lightweight, inexpensive, handheld fluorometer, configured for the fluorescent probes commonly used for nucleic acid and protein quantitation....
... a spectro-fluorometer supplied by HORIBA ... a new type of spectro-fluorometer ... various components. The flexible system ... choose components that best suit ...
Medicine Products: