Navigation Links
Medivation Announces Positive New Efficacy Data From Phase 1-2 Trial of MDV3100 in Advanced Prostate Cancer Patients
Date:6/2/2009

-- Findings Presented at American Society of Clinical Oncology 2009 Annual Meeting and Included in Best of ASCO(R) Educational Program --

SAN FRANCISCO, June 2 /PRNewswire-FirstCall/ -- Medivation, Inc. (Nasdaq: MDVN) today announced the presentation of new clinical results from a Phase 1-2 trial evaluating MDV3100, a next-generation androgen receptor antagonist, in castration-resistant prostate cancer (CRPC) patients. The new findings, which include data from all 140 enrolled patients, confirm previously reported results that MDV3100 consistently demonstrated anti-tumor activity in both chemotherapy-naive and post-chemotherapy CRPC patients across dose levels and endpoints, as evaluated by reductions in prostate specific antigen (PSA) levels, radiographic findings and circulating tumor cell (CTC) counts.

New findings include the median time to PSA progression, which was 6.1 months for post-chemotherapy patients, with the median time not yet reached for chemotherapy-naive patients. In addition, the median time to radiographic progression was 6.6 months for post-chemotherapy patients, with the median time not yet reached for chemotherapy-naive patients.

"These new clinical data in the post-chemotherapy setting are encouraging because these patients have a poor prognosis, surviving on average a year or less -- with no approved treatment options," said Howard Scher, M.D., principal investigator of the trial and chief of the Genitourinary Oncology Service and the D. Wayne Calloway Chair in Urologic Oncology at Memorial Sloan-Kettering Cancer Center in New York. "These findings suggest that MDV3100, with its unique mechanism of action, provides beneficial clinical effects in contrast to those achieved with first-generation androgen receptor antagonists."

In vitro data recently published in Science'/>"/>

SOURCE Medivation, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Pfizer and Medivation Initiate Phase 3 Trial of Dimebon Added to Donepezil in Patients with Alzheimers Disease
2. Medivation Completes Enrollment of Phase 1-2 Trial of MDV3100 in Castration-Resistant Prostate Cancer Patients
3. Medivation Presents Positive New Data on Dimebons Long-Term Efficacy and Novel Mechanism of Action at the International Conference on Alzheimers Disease
4. Medivation Announces Publication in The Lancet of Dimebon Pivotal Trial Results in Alzheimers Disease
5. Medivation Announces Positive Top-Line Results From Phase 2 Dimebon Study in Huntingtons Disease
6. Medivation to Host Conference Call at 5 p.m. EDT Monday to Discuss Top-Line Phase 2 Study Results in Huntingtons Disease
7. Medivation Initiates Second Pivotal Phase 3 Trial of Dimebon(TM) in Patients With Alzheimers Disease
8. Medivation Announces Presentation of Positive MDV3100 Clinical Data in Castration-Resistant Prostate Cancer Patients at 44th ASCO Annual Meeting
9. Medivation Announces Presentation of MDV3100 Clinical Data in Patients With Castration-Resistant Prostate Cancer at 44th American Society of Clinical Oncology Annual Meeting
10. Medivations Dimebon(TM) Significantly Improved Thinking and Memory in Alzheimers Disease Patients Over One Year
11. Medivations Dimebon(TM) Significantly Improved Daily Function in Alzheimers Disease Patients, Resulting in Reduced Need for Caregiver Assistance
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... , Aug. 20, 2014   Ventana Medical ...  Group, today announced that its VENTANA System for ... in the European Union for routine pathology, including ... consisting of VENTANA Virtuoso software coupled with either ... HT slide scanner, provides automated digital slide creation, ...
(Date:8/20/2014)... and PHOENIX , ... established to bring cutting-edge next-generation sequencing and proteomic ... patients, today announced a collaboration with TESARO, Inc.  ... characterize patient tissue samples from clinical trials to ... resistant to TESARO,s TSR-011.  This may lead to more ...
(Date:8/20/2014)... , Aug. 20, 2014 Reportlinker.com announces that ... catalogue: Global Feminine Hygiene Products Industry ... analyzes the worldwide markets for Feminine Hygiene Products in ... Tampons, Panty liners, and Others. The report provides separate ... , Japan , Europe ...
Breaking Medicine Technology:Full digitization of the anatomic pathology lab is here with the VENTANA System for Primary Diagnosis 2Full digitization of the anatomic pathology lab is here with the VENTANA System for Primary Diagnosis 3Paradigm Announces Molecular Profiling Collaboration with TESARO, Inc. 2Global Feminine Hygiene Products Industry 2Global Feminine Hygiene Products Industry 3Global Feminine Hygiene Products Industry 4Global Feminine Hygiene Products Industry 5Global Feminine Hygiene Products Industry 6Global Feminine Hygiene Products Industry 7Global Feminine Hygiene Products Industry 8Global Feminine Hygiene Products Industry 9Global Feminine Hygiene Products Industry 10Global Feminine Hygiene Products Industry 11Global Feminine Hygiene Products Industry 12Global Feminine Hygiene Products Industry 13Global Feminine Hygiene Products Industry 14Global Feminine Hygiene Products Industry 15Global Feminine Hygiene Products Industry 16Global Feminine Hygiene Products Industry 17Global Feminine Hygiene Products Industry 18Global Feminine Hygiene Products Industry 19Global Feminine Hygiene Products Industry 20Global Feminine Hygiene Products Industry 21Global Feminine Hygiene Products Industry 22Global Feminine Hygiene Products Industry 23Global Feminine Hygiene Products Industry 24Global Feminine Hygiene Products Industry 25Global Feminine Hygiene Products Industry 26
(Date:8/20/2014)... Botanica Day Spa ... the new and popular stem cell line from ... and wrinkles and naturally repairs the skin. The ... new service by offering clients a complimentary dermaplaning ... facial. , Pevonia® continues to be a global ...
(Date:8/20/2014)... has been chosen by Plymouth University to be an ... April 2009 to raise awareness of, and funding for, ... brain tumour patients. , A range of events and ... the charity, and members of staff and students, as ... donate, fundraise and volunteer. The involvement of the wider ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 If old age ... a cure for it. With extensive research on HGH and ... ‘MetroMD’ claims to have perfected the art of rubbing off ... brand new younger look with their revolutionary anti-aging hormone therapy ... the 21st century fountain of youth, the MD of MetroMD, ...
(Date:8/20/2014)... (PRWEB) August 20, 2014 New Jersey’s ... needs of an estimated tens of thousands of patients ... new Bill A3525—a bill that would expand the list ... their own cannabis—earlier this summer by State Assemblywoman Linda ... medicinal quality marijuana is growing. , To help fill ...
(Date:8/20/2014)... In a recent article published by ... London (UCL) study showed that dental experts from around ... teeth was the most effective. Analysis of 66 different ... were frequently recommended, but none were favored by a ... experienced cosmetic dentist Dr. Patrick J. Broome, ...
Breaking Medicine News(10 mins):Health News:New Stem Cell Facial Unveiled at Botanica Day Spa 2Health News:New Stem Cell Facial Unveiled at Botanica Day Spa 3Health News:Plymouth University chooses Brain Tumour Research as official charity 2Health News:MetroMD Offers Revolutionary Anti-aging Hormone Therapy in Hollywood Area 2Health News:Oaksterdam University to Host Four-Day Educational Marijuana Horticultural Seminar Aug 23-26; Training Fills Information Gap for Medical Marijuana Caregivers and Patients 2Health News:Oaksterdam University to Host Four-Day Educational Marijuana Horticultural Seminar Aug 23-26; Training Fills Information Gap for Medical Marijuana Caregivers and Patients 3Health News:Ending Confusion About the Best Way to Brush Teeth 2Health News:Ending Confusion About the Best Way to Brush Teeth 3
... Nanophase Technologies (Nasdaq: NANX ) ... products, announced today that the Company accepted the resignation ... Chief Technology Officer, so that he may pursue new ... several of the Company,s key patents and served as ...
... 3 WXYZ is proud to announce that ... Peter Nielsen , will now be seen exclusively on Channel ... than 15 years Peter Nielsen has hosted the nationally syndicated ... the author of numerous books and videos on health and fitness and ...
... the day has surprising impact on young people GAITHERSBURG, ... the importance of breakfast for students, Sodexo, a leading ... 470 school districts across the country, has created a ... time for National School Breakfast Week, March 2-6."Studies repeatedly ...
... to Improve, Automate Health Care in Master-Planned CommunitiesSCOTTSDALE, Ariz., ... of acres across the West but it,s his company,s ... would radically alter the use of energy grids. ... that message this week to The Wall Street Journal,s ...
... Exhibit www.donaldverger.com PORTLAND, Maine, March 3 A ... jail over a period of three days at ... the charges were dismissed, Verger was compelled to ... http://www.newscom.com/cgi-bin/prnh/20090303/NE78221 )"We are deeply grateful to Mr. ...
... of Pennsylvania School of Medicine and the University ... cells that spur misplaced bone growth. Unexpectedly, the ... vessels deep within skeletal muscle and other connective ... work also shows that cells important in the ...
Cached Medicine News:Health News:Nanophase Announces Changes in Principal Officers and Directors 2Health News:Nanophase Announces Changes in Principal Officers and Directors 3Health News:Peter Nielsen Has a New Home on WXYZ-TV! 2Health News:Sodexo Shares Top Breakfast Benefits for Students 2Health News:Innovative Plans by Major Arizona-Based Developer Sparks Landmark Energy Conservation Legislation in Multiple States to Urge Federal Action at Wall Street Journal Conference This Week with Gore, Google CEO & T. Boone Pickens 2Health News:Award Winning Photographer and Museum Founder to Donate Iconic Images In Support of the Innocence Project 2Health News:Award Winning Photographer and Museum Founder to Donate Iconic Images In Support of the Innocence Project 3Health News:Award Winning Photographer and Museum Founder to Donate Iconic Images In Support of the Innocence Project 4Health News:Misplaced metamorphosis 2
... innovative B-Twin Expandable Spinal System is intended ... The Implant - preloaded on its Delivery ... intervertebral space in a reduced configuration of ... up to 15mm (depending on the size ...
... on the Alpha 5 include a newly ... digital processor specifically designed for ultrasonic signals. ... reduces image speckle and enables clearer imaging ... The enhanced user confidence afforded by Alpha ...
... NCP-2, ACS proudly introduces full disclosure to ... tools for assessing the administration of ECP ... ECP Treatment Report.,The ACS Treatment Report is ... both physicians and therapists to review patient ...
... monitors and controls patient temperature primarily in ... surgery, trauma, or other medical conditions. The ... provided from a patient temperature probe. Circulating ... and 42C (107.6F) to achieve a preset ...
Medicine Products: