Navigation Links
Medical Research Council Technology's Centre for Therapeutics Discovery Opens its First 'Call For Targets' in an Effort to Develop Drugs in Areas of Serious Unmet Need
Date:2/3/2010

LONDON, February 4 /PRNewswire/ -- A major centre created by the Medical Research Council (MRC) and MRC Technology (MRCT) in order to fast-track the discovery and development of novel drugs, opens its first call for targets today.

The MRCT Centre for Therapeutics Discovery (CTD), based in London, is seeking small molecule drug discovery and therapeutic antibody targets from academic researchers.

The CTD would like to collaborate with scientists in all universities to develop drug discovery projects targeting diseases for which there is significant unmet need. The centre will apply state of the art computational and medicinal chemistry to produce 'drug-like' molecules with the potential to become therapies. It will also focus on developing novel antibody therapies, bringing to bear its world-class expertise in antibody humanization technology, which has already produced two marketed therapeutic antibodies, with several more currently in clinical development.

As such, the CTD is also continuing to recruit and re-employ first class scientists from Pharma companies to build and maintain a high quality drug discovery capability within the UK.

In building the CTD, MRCT is helping to position the UK at the forefront of academic based drug discovery World-wide, creating a Centre of Excellence that Pharma companies will want to link to and hence maintain a Pharma presence in the UK.

Scientists from academia will benefit from the wealth of the CTD's expertise including provision of tool compounds and reagents (including monoclonal antibodies) for further target validation and characterization studies, in silico screening, and access to medicinal chemistry, screening technologies and ADMET. CTD will also provide academia access to its hybridoma production capability and its extensive antibody engineering and expression expertise as well as its core antibody humanization skills. This initiative will also enable UK scientists to tap into MRC's recently announced Developmental Pathway Funding Scheme (DPFS) and collaborate with a high quality drug discovery capability whilst retaining existing IP ownership.

Dr David Tapolczay, MRCT's CEO explained: "This is a fantastic opportunity for academics to have a dedicated centre with which to collaborate and progress their science to deliver tangible clinical benefit. In so doing, this initiative will help the UK to retain its world-leading reputation for innovation in drug discovery."

Researchers are asked to visit http://www.callfortargets.org to request a submission application form for their targets. Capacity for stage 1 on the programme is limited, so researchers are encouraged to submit their targets as soon as possible.

    Notes to Editors
    About MRCT's Centre for Therapeutics Discovery (CTD)

    - CTD' s Therapeutic Antibody group - no-one else has the
      capability to raise and humanise rodent monoclonals for clinical
      benefit.

    - Within the small molecule arena, our medicinal chemistry
      capability is extensively Pharma trained, which is not the norm for
      academic based drug discovery, where most other groups have been built
      primarily from academic based chemists. This gives us a distinct edge
      as our chemists have been involved in Pharma quality drug discovery for
      many years and have brought with them that experience.

    - The combination of having a small molecule as well as
      antibody drug discovery capability makes us unique.

About Medical Research Council Technology (MRCT)

MRCT is the exclusive commercialisation agent for the UK Medical Research Council, working to translate cutting edge scientific discoveries into commercial products. MRCT bridges the gap between innovative basic science and making medicine. MRCT works to provide drug-like candidate molecules to innovative new drug targets, and to translate innovative antibody-based drug targets into potent and selective therapeutic antibody candidates giving pharmaceutical and biotechnology companies new starting points for drug discovery and development, based on MRC advances in science. MRCT's Therapeutic Antibody Group scientists have a proven track record of success in antibody humanization which extends over 20 years and has produced 10 clinical candidates and two regulatory approved humanized antibodies: Elan/Biogen Idec's Tysabri(R) and Chugai/Roche's Actemra(R). http://www.mrctechnology.org

About Medical Research Council

For almost 100 years the Medical Research Council has improved the health of people in the UK and around the world by supporting the highest quality science. The MRC invests in world-class scientists. It has produced 29 Nobel Prize winners and sustains a flourishing environment for internationally recognised research. The MRC focuses on making an impact and provides the financial muscle and scientific expertise behind medical breakthroughs, including the first antibiotic penicillin, the structure of DNA and the lethal link between smoking and cancer. Today MRC funded scientists tackle research into the major health challenges of the 21st century. http://www.mrc.ac.uk

    Press Release Reference: MRCT040210

    Contact Information:

    Medical Research Council Technology (MRCT):
    Jan Coates
    Business Development Officer
    MRC Technology
    E-mail: jan.coates@tech.mrc.ac.uk
    Phone: +44-(0)20-8906-7183
    Website: http://www.mrctechnology.org


SOURCE Medical Research Council Technology (MRCT)


'/>"/>
SOURCE Medical Research Council Technology (MRCT)
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Harvard Medical School-Partners HealthCare Center for Genetics and Genomics Successfully Completes Evaluation of AutoGenomics 2C9-VKORC1 Panel to Assess Warfarin Sensitivity
2. You May Have a Thyroid Problem and Not Know It - Particularly If Youre Over 60, Says a New Harvard Medical School Report
3. Harvard Medical School-Partners HealthCare Center for Genetics and Genomics Successfully Completes Evaluation of AutoGenomics 2C9-VKORC1 Panel to Assess Warfarin Sensitivity
4. Globus Medical Raises $110 Million in Series E Financing Round
5. Quark Pharmaceuticals Appoints New Chief Medical Officer
6. Boston University Biomedical Engineers Find Chink in Bacterias Armor
7. Rochester Medical Anti-Infection Foley Catheter Demonstrates Effectiveness in Randomized Trial
8. Rockwell Medical Technologies, Inc. Begins Patient Enrollment for its SFP Dose-Ranging Study
9. Flexible Medical Systems Raises $1.2M Seed Investment for Initial Human Trials
10. Cleveland Clinic Summits to Focus on Cardiovascular Medical Innovation
11. Rockwell Medical Technologies, Inc. Begins Dosing Patients for SFP Phase IIb Clinical Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/24/2017)... India , March 24, 2017 Abdominal Aortic Aneurysm Repair ... million by 2022, Globally, registering a CAGR of 5.1% from 2016 to 2022. The ... projected to dominate the market during the study period. ... ... ...
(Date:3/24/2017)... -- Research and Markets has announced the addition ... report to their offering. ... Pain Management in the U.S.: ... physical pain, emphasizing consumer survey analysis, including trends over time. ... who have selected illnesses/conditions strongly associated with physical pain and ...
(Date:3/24/2017)... FinancialBuzz.com News Commentary   ... Medical cannabis products around the world are projected to gain popularity. ... cannabis market will reach a value of USD 55.8 billion by 2025. ... new growing industry. By the end of 2016, 28 states have now ... More conservative states like Arkansas and ...
Breaking Medicine Technology:
(Date:3/27/2017)... ... ... still in shock after receiving a $2,500 Academic Award from California Casualty . “This ... She thinks the coming week is going to be a very joyful for her classroom. ... students.” , The award will allow the 4th grade teacher at Tumwater Hill Elementary School ...
(Date:3/27/2017)... ... March 27, 2017 , ... ?Grow Healthy ... resolve the pending litigation between itself and 1800 Vending DBA Healthy You Vending. ... “I am thrilled to announce that we have now reached a settlement agreement ...
(Date:3/26/2017)... (PRWEB) , ... March 26, 2017 , ... ... worldwide to receive the RealSelf 100 Award, a prestigious award honoring the top ... procedures and to find and connect with doctors and clinics. , In 2016, ...
(Date:3/24/2017)... York, NY (PRWEB) , ... March 24, 2017 ... ... campaign: “Fighting Infection,” which will spark a conversation on the current obstacles facing ... the number of completely preventable deaths caused by these infections. , The ...
(Date:3/24/2017)... ... March 24, 2017 , ... Texas Physical Therapy Specialists (TexPTS) is ... 9618 Huebner Road. The clinic is the group’s 7th location in San Antonio and ... Higgins, PT, will provide care from the clinic, which opened March 22, 2017. ...
Breaking Medicine News(10 mins):