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Medgenics Announces Positive Data From Phase I/II Clinical Trial of EPODURE Treatment of Anemia in Chronic Kidney Disease
Date:2/3/2009

These continuing results demonstrate that EPODURE can provide a sustained therapy for anemia. We are aware of no other anemia therapy that has demonstrated maintenance of hemoglobin levels for months from a single treatment. Our results thus far appear to offer a major advantage over current therapies and to represent a paradigm shift in the treatment of anemia. More generally, these results suggest that Medgenics' Biopump may offer the first practical treatment to provide sustained protein therapy and serve as an alternative to expensive, bolus injections of proteins mass-produced in animal cells."

Medgenics' Biopump is a unique tissue-based platform technology that processes a toothpick sized sliver of the inner layer of the subject's skin and is intended to provide sustained-action protein therapy for the treatment of a range of chronic diseases, including Hepatitis C, hemophilia, and multiple sclerosis. The technology represents a major advancement over today's protein therapy which involves frequent, costly, and painful bolus injections. A breakthrough in personalized medicine, the Biopump is intended to increase efficacy, reduce side effects, and improve patient compliance and quality of life, as well as lower treatment costs and extend treatment to populations currently under-treated.

Medgenics intends to develop its technology for a variety of chronic conditions, initially focusing on anemia and hepatitis C, with the intent to bring it to market via multiple strategic alliances in the relevant therapeutic space. The Company is in active discussions with major potential strategic partners for one or more applications.

"We are excited by the continued and sustained positive trial results, as well as the strong interest we are receiving from several potential partners," concluded Dr. Pearlman. "The EPODURE Biopump represents the first of a line of Biopump products designed to vastly improve the treat
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