Navigation Links
Medarex Announces Initiation of Phase 2 Clinical Development Program for the Treatment of Lupus
Date:8/12/2008

interferon-alpha. Published data indicate that levels of interferon-alpha are elevated in many patients with active SLE and other autoimmune disorders, and may be associated with disease activity. Preclinical data from animal models suggest that MEDI-545 may suppress the abnormal immune activity associated with lupus by binding to multiple interferon-alpha subtypes seen in the serum of lupus patients.

In November 2004, MedImmune entered into a collaboration with Medarex to focus on two specific antibodies, one of which was MDX-1103 (now known as MEDI-545). Under the terms of the agreement, MedImmune is responsible for all ongoing clinical development activities. Prior to the beginning of pivotal studies, Medarex may elect to co-develop the products in return for the opportunity to co-promote and to receive a share of the commercial profits in the United States. In all other cases, Medarex will be entitled to receive milestone payments and royalties.

About Lupus

Approximately 350,000 individuals in the United States are affected with lupus, a chronic inflammatory disease that causes the body to attack its own tissues and organs, including the skin, joints, blood and kidneys. Treatments for lupus include anti-inflammatory drugs, antimalarials, corticosteroids and drugs approved for other purposes, such as immunosuppressive agents given to cancer patients undergoing chemotherapy or medicines developed to treat arthritis patients. Lupus occurs about 10 times more frequently in adult females than adult males, and is two to three times more common among African Americans, Hispanics, Asians and Native Americans.

About Medarex

Medarex is a biopharmaceutical company focused on the discovery, development and potential commercialization of fully human antibody-based therapeutics to treat life-threatening and debilitating diseases, including cancer, inflammation, autoimmune disorders and infectious diseases. Medarex applies its UltiMAb(R) tec
'/>"/>

SOURCE Medarex, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Medarex Announces Allowance of Investigational New Drug Applications for Wholly Owned Fully Human Anti-CD19 Antibody, MDX-1342
2. Medarex to Receive Milestone Payment from Amgen
3. Medarex Announces Ipilimumab Program Continues to Move Forward
4. Medarex Reports Interim Data from Ongoing Ipilimumab Combination Phase 1 Studies in Prostate Cancer at American Association for Cancer Research Meeting
5. Medarex Announces Presentations at Annual Meeting of the American Society of Clinical Oncology
6. Medarex Announces Initiation of Phase 2 Clinical Trials for the Treatment of Ulcerative Colitis and Rheumatoid Arthritis
7. Medarex Highlights Strength in Antibody Development and Underlying Pipeline Strategy at R&D Day Event in New York City
8. Medarex Announces Allowance of Investigational New Drug Application for Wholly-Owned Fully Human Anti-PD-L1 Antibody, MDX-1105
9. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
10. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
11. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/31/2014)... MONROVIA, Calif., July 31, 2014 Xencor ... biopharmaceutical company developing engineered monoclonal antibodies for the ... and cancer, today reported financial results for the ... review of recent business highlights. "In ... the American Thoracic Society 2014 International Conference (ATS) ...
(Date:7/31/2014)... Calif. , July 31, 2014  Cepheid (NASDAQ: ... speaking at the following conferences, and invited investors to participate ... Access Conference, New York, NY Wednesday, ... Baird Health Care Conference, New York, NY ... Time , Accessing Live Webcasts To access the ...
(Date:7/31/2014)... MOUNTAIN VIEW, Calif. , July 31, 2014 ... ) today provided an update on its pipeline ... of 2014, Alexza expects to initiate a Phase ... which is being developed for the management of ... identified two new Staccato -based product candidates ...
Breaking Medicine Technology:Xencor Reports Second Quarter 2014 Financial Results 2Xencor Reports Second Quarter 2014 Financial Results 3Xencor Reports Second Quarter 2014 Financial Results 4Xencor Reports Second Quarter 2014 Financial Results 5Xencor Reports Second Quarter 2014 Financial Results 6Xencor Reports Second Quarter 2014 Financial Results 7Xencor Reports Second Quarter 2014 Financial Results 8Cepheid to Webcast Upcoming Financial Presentations 2Alexza Provides Pipeline Update 2Alexza Provides Pipeline Update 3Alexza Provides Pipeline Update 4Alexza Provides Pipeline Update 5Alexza Provides Pipeline Update 6
(Date:7/31/2014)... In many states and counties across the country, ... necessary life saving drugs. This requirement is for the safety ... high number of ambulances without proper security procedures. , In ... and even replaces the vital pain killers with saline. Later, ... the case in Baraboo, Wisconsin last November. According to court ...
(Date:7/31/2014)... SC (PRWEB) July 31, 2014 In today’s ... increasingly difficult to get. Snoring and sleep apnea (a medical ... robs people and their bed partners of the rest they ... 45% of the population snores and 20 million people in ... 10% have been diagnosed and treated; and of those treated, ...
(Date:7/31/2014)... Adventist Health System, which is ... Florida Hospital Tampa, Florida Hospital Carrollwood, Florida Hospital ... Pinellas, Florida Hospital Wesley Chapel, Florida Hospital Zephyrhills, ... Heartland Medical Center Lake Placid and Florida Hospital ... Most Wired Hospitals and Health Systems, which is ...
(Date:7/31/2014)... Peninsula, MI (PRWEB) July 31, 2014 The ... preparation of the upcoming harvest. And, to celebrate, folks are ... Saturday and Sunday, September 6 and 7, 2014 along the ... festivities is an optional walk or run through the vineyards ... Winery in Suttons Bay. A unique course between rows of ...
(Date:7/31/2014)... Weblify has finally been released by marketing and advertising ... The result is a perfected and fine tuned platform ... minutes without knowing any HTML or other programming languages. , ... SEO expert, agrees that this platform allows anyone to create ... web site builders out there, but this is truly unique. ...
Breaking Medicine News(10 mins):Health News:New MedixSafe Alert - Ambulances Must Have A Medical Safe, Narcotics Cabinet, or Drug Locker 2Health News:Snoring: Bad for Relationships, Bad for Health 2Health News:Snoring: Bad for Relationships, Bad for Health 3Health News:Florida Hospital West Florida Region is Among the Most Wired Hospitals and Health Systems in the United States 2Health News:Leelanau Peninsula’s Annual Harvest Stompede Offers a Unique Vineyard Course for Walkers, Runners and Wine Tasters 2Health News:Weblify Review Exposes Ricky Mataka And His New Site Building Platform 2Health News:Weblify Review Exposes Ricky Mataka And His New Site Building Platform 3
... The following was,written by Andrew F. Flusche, ... control. Why can Planned,Parenthood freely market birth control ... array of restrictions?, Fifty years ago, people ... people smoked, especially highly visible public figures and,celebrities. ...
... National,Community Pharmacists Association (NCPA) is pleased today to ... of public affairs., "We,re pleased to have ... affairs team," said Bruce Roberts, RPh, NCPA Executive ... Hill, and,Administration experience will undoubtedly increase our organization,s,volume ...
... Fla., Oct. 11 Florida,s hospitals and the,Coalition ... for,signing a bill today to restore no-fault auto ... especially those injured in auto,accidents. Governor Crist,s ... no-fault,auto insurance system, and mandatory Personal Injury Protection ...
... found levels of protein indicating damage returned to ... (HealthDay News) -- Preliminary research suggests that potent AIDS ... people infected with HIV. , The findings are based ... testing, so it,s not clear exactly what they mean ...
... CAH ), a global provider of products and services that ... first-quarter,results for its fiscal 2008 on Monday, Nov. 5, prior ... The company has scheduled a conference call for Nov. ... the call and corresponding slide,presentation, go to the Investor page ...
... Transfer to Healthcare Marketplace -, ATLANTA, Oct. ... community management (BCM) solutions, today announced it,is sponsoring ... Electronic Data Interchange (WEDI) Conference on Health Savings,Accounts ... BizManager,suite and Secure Link solution. The conference is ...
Cached Medicine News:Health News:Sue Birth Control Companies for Your Health, Says American Life League 2Health News:Sue Birth Control Companies for Your Health, Says American Life League 3Health News:Sue Birth Control Companies for Your Health, Says American Life League 4Health News:Lisa Camooso Miller Joins National Community Pharmacists as Vice President of Public Affairs 2Health News:Hospital Coalition Says Governor's No-Fault Bill Signing Provides a 'Great Protection' for Florida Consumers 2Health News:AIDS Drugs May Protect Brain 2Health News:Cardinal Health To Announce First-Quarter Results on November 5 2Health News:Inovis Sponsors ASC X12 Conference, Exhibits BizManager and Secure Link 2
... used for endophotocoagulation indications, ... uncompromised laser treatment of ... handpieces are compatible with ... (532 nm), OcuLight infrared ...
... The AT555 utilizes a patented hands-free automatic ... staff to take an accurate IOP measurement ... the headrest to the left or right ... head against the comfortable headrest pad. The ...
The Perkins has been established for well over 20 years as a "world standard" for hand held applanation tonometers....
The new TOPCON 8800 Series of auto refractors and auto kerato-refractors satisfies the needs of today's demanding eyecare practice !...
Medicine Products: