Navigation Links
MedImmune's Motavizumab Reduced RSV Hospitalizations by 83 Percent Among High-Risk Native American, Full-Term Infants in Placebo-Controlled Phase 3 study
Date:8/23/2007

in infants in the United States. RSV is the most common respiratory infection in infancy or childhood. Approximately one-half of all infants are infected with RSV during the first year of life, and nearly all children have been infected at least once by the time they reach their second birthday. Children born prematurely as well as those with chronic lung disease (CLD) or congenital heart disease (CHD) are at highest risk for severe disease and hospitalization due to RSV. The virus may also cause severe illness in other high-risk groups such as the elderly, those with underlying respiratory or cardiac disease, and those with compromised immune systems (e.g., bone marrow transplant patients).

About Motavizumab

Motavizumab, formerly known as Numax(R), is an investigational humanized MAb being evaluated for its potential to prevent serious lower respiratory tract disease caused by RSV in pediatric patients at high risk of RSV disease. Phase 1 and Phase 2 study data have been reported showing that motavizumab appears to have a similar safety and pharmacokinetic profile to Synagis in infants. Additionally, in early phase studies children treated with motavizumab had reduced RSV replication in the upper respiratory tract. In its first pivotal trial, which was a head-to-head comparative trial with Synagis, motavizumab demonstrated a 26-percent reduction in RSV hospitalizations due to RSV and a 50-percent reduction in the incidence of RSV lower respiratory tract infections requiring outpatient management, its secondary endpoint.

About Synagis

Synagis is the only monoclonal antibody approved by the FDA to help prevent an infectious disease. Synagis was approved for use in the United States in 1998, Europe in 1999, and Japan in 2002. Synagis is currently available in 62 countries.

Synagis is indicated for the prevention of serious lower respiratory tract disease caused by respiratory syncytial virus (RSV) in pediatric patients at high risk of RS
'/>"/>

SOURCE MedImmune, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. New Study Shows That Extending Prophylaxis With Clexane / Lovenox (enoxaparin Sodium Injection) to 5 Weeks is More Effective Than 10 Days for Reducing the Risk of Venous Thromboembolism (VTE) in Acutely ill Medical Patients With Reduced Mobility
2. Publication on Pixantrone Preclinical Studies Demonstrates Reduced Cardiotoxicity Compared to Equiactive Doses of Doxorubicin and Mitoxantrone
3. New Study Shows A1c Reduced Safely By Patients With Type 2 Diabetes Using Self-Adjusted Dosing Starting With Once-Daily Insulin Treatment Levemir
4. Lipitor Reduced the Risk of Coronary Events by Half and Stroke by Nearly One-Third in High-Risk Patients with Type 2 Diabetes Who Experienced a Recent Stroke
5. New Study Shows A1c Reduced Safely By Patients With Type 2 Diabetes Using Self-Adjusted Dosing Starting With Once-Daily Insulin Treatment Levemir
6. Arterial Plaque Significantly Reduced in Women Age 50-59 Taking Hormones, Says New Analysis of Womens Health Initiative Data
7. New Analysis of WHI Data Shows Reduced Levels of Coronary Artery Calcification, a Predictor of Cardiovascular Events, in Women aged 50-59 taking Estrogen Therapy
8. Pivotal Phase III Trial Showed Promacta (eltrombopag olamine) Raised Platelet Counts and Reduced Bleeding in Patients With Chronic ITP
9. Preclinical Study Finds Protease Inhibitor-Resistant HIV May Have Reduced Potential to Develop Resistance to Panacos Bevirimat
10. New Analysis of Data Shows Treatment With Abbotts Humira (Adalimumab) Significantly Reduced Disease-Related Hospitalization for Patients with Crohns Disease
11. Data Suggest Cymbalta Reduced Severity of Night Pain in Patients with Diabetic Nerve Pain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... 2014 PCCA received the Autism Hope ... ) program seal for best practices in meeting ... medical practices, materials and goods that meet strict ... Children affected by autism often have unique physical ... ingredients found in food and medicine – for ...
(Date:12/15/2014)... --Research and Markets , ... announced the addition of the "Cardiac Guidewires - ... offering. Global Guidewires sector is projected to reach ... accounts for nearly 35% (2015) of the ... approximately 25% (2018). Asia-Pacific is ...
(Date:12/15/2014)... Dec. 15, 2014  Colorado and Washington State ... adult use of cannabis. Oregon , ... ended prohibition during the November 2014 elections. ... http://photos.prnewswire.com/prnh/20141212/164153LOGO The benefits of legalizing ... obvious benefits like the increased tax revenue for state and ...
Breaking Medicine Technology:Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 2Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 3Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 2Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 3Cardiac Guidewires - Global Trends, Estimates and Forecasts, 2012-2018 4CannaInsider.com Estimates 200,000 New Jobs in the Cannabis Industry by 2015 2
... LLC, a leading developer of stereotactic radiosurgery and ... newest CyberKnife cancer center, which will begin treating ... Developed through a partnership between Accelitech, physicians and ... of Chicago will provide state-of-the-art CyberKnife treatment to ...
... Pharmaceuticals, Inc. (NYSE: WPI ), a leading ... President and Chief Executive Officer, will provide an overview ... RBC Capital Markets, Healthcare Conference on Tuesday, February 28, ... York Palace in New York, New York.  The presentation ...
Cached Medicine Technology:Accelitech to Open the First CyberKnife Cancer Center Within the City of Chicago 2
(Date:12/15/2014)... Cancer researchers have just published an ... of deadly malignant pleural mesothelioma. Surviving Mesothelioma has just ... Click here to read it now. , ... Center, and New York’s Langone Medical Center performed complete ... in an effort to pinpoint the genes that ...
(Date:12/15/2014)... Beach, FL (PRWEB) December 15, 2014 South ... , knows that holidays can be a daze of hassle, ... slips and falls while decking halls, to burns when making ... of holiday hazards that can happen at any time. To ... pain, MD Now has made a list of helpful and ...
(Date:12/15/2014)... MA (PRWEB) December 15, 2014 ... management solutions, announced today that it has received ... Quality Assurance (NCQA) for its Disease Management (DM) ... pulmonary disease (COPD), coronary heart disease and diabetes. ... from NCQA for Health Dialog’s Disease Management (DM) ...
(Date:12/15/2014)... (PRWEB) December 15, 2014 The increase in ... one of the main factors which is contributing to the ... for the diagnosis and treatment of hearing loss and balance ... of three parts - microphone, speaker and amplifier. The global ... rate of 6.01% during the period from 2014 to 2019. ...
(Date:12/15/2014)... 2014 In support of high-quality ... to restrictive state laws that may have unintended ... important area of public health policy. , The ... Integrity of Independent Review, contends that state legislation ... peer review determinations can result in subpar outcomes ...
Breaking Medicine News(10 mins):Health News:New Study Reveals Genetic Mutations That May Trigger Mesothelioma, According to Surviving Mesothelioma 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 2Health News:MD Now Urgent Care Presents Healthy Holiday Tips 3Health News:Health Dialog Receives NCQA Accreditation for Disease Management Programs 2Health News:Audiological Devices Market 2019 Demand for Esthetic Hearing Aids Drives the Growth, Says a Report at ReportsnReports.com 2Health News:Audiological Devices Market 2019 Demand for Esthetic Hearing Aids Drives the Growth, Says a Report at ReportsnReports.com 3Health News:Audiological Devices Market 2019 Demand for Esthetic Hearing Aids Drives the Growth, Says a Report at ReportsnReports.com 4Health News:NAIRO Calls for Higher Quality Independent Peer Review By Ending Restrictive State Laws 2
... believe that hair loss for,both men and women is a ... approach to help our clients that worked unlike many potions,lotions ... Revage 670(TM),because it is the only true hair regeneration laser ... by Harvard Medical, Northwestern,University , Mass General, etc.). ...
... 15 The Musculoskeletal Transplant,Foundation (MTF) announced today ... the,development phase in its efforts to develop a ... Orthofix International N.V. (Nasdaq:, OFIX ). ... package to Orthofix,which confirms the relative superiority of ...
... Inc.,(NYSE: DVA ), today announced that it ... Services, Office of Inspector General ("OIG") to respond to ... civil,investigation by the Department of Justice and the U.S. ... in the Company,s,Quarterly Report on 10-Q for the period ...
... 15 Hundreds of Aflac agents and,employees will be ... swabbed,as part of a new company initiative to boost the rolls ... program kicks off at the company,s annual,national sales conference on December ... bone marrow registration effort was inspired by Steve Karas, an Aflac,regional ...
... fighting infection than during the day, study says , , MONDAY, ... does a sick body good, new research says. , Stanford ... fights invading bacteria the hardest at night and the least ... at the American Society for Cell Biology annual meeting, in ...
... sharper young drivers, study suggests , , MONDAY, Dec. 15 (HealthDay ... the school day a bit later may lower their odds ... , The researchers found a 16.5 percent drop in auto ... the start of classes from 7:30 a.m. to 8:30 a.m. ...
Cached Medicine News:Health News:Musculoskeletal Transplant Foundation Announces Major Development Milestone in Stem Cell Allograft Product 2Health News:Musculoskeletal Transplant Foundation Announces Major Development Milestone in Stem Cell Allograft Product 3Health News:DaVita Inc. Announces Receipt of DOJ Subpoena in Connection with Previously Reported Investigation 2Health News:Aflac Agents and Employees Boost Bone Marrow Registry 2Health News:Aflac Agents and Employees Boost Bone Marrow Registry 3Health News:Immune System Works Better at Night 2Health News:Later School Start Time Cuts Teens' Car Crash Risk 2Health News:Later School Start Time Cuts Teens' Car Crash Risk 3
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: