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MedAvante Launches Service to Boost Reliability of Assessments to Reduce Risk of Failed Alzheimer's Disease Trials
Date:6/2/2010

HAMILTON, N.J., June 2 /PRNewswire/ -- MedAvante, Inc., the leader in centralized evaluation of central nervous system (CNS) disorders, announced today it was launching its CQC Continuous Quality Control Service for trials assessing Alzheimer's Disease. Its CQC Services are already in use for trials of other central nervous system disorders including depression, anxiety and schizophrenia in the United States, Europe, Asia, Latin America and South Africa.

The number of Americans with Alzheimer's Disease exceeds 5 million, and the Pharmaceutical Research and Manufacturers of America estimates there are 27 medications in development for Alzheimer's, with more than 200 trials recruiting patients. In Alzheimer's trials, like other CNS trials, patients are evaluated using rating scales that must be administered and interpreted by professionals. It is critical that such evaluations be accurate and consistent from the beginning of a study until the end to preserve the validity of the trial.

"In Alzheimer's Disease trials, which tend to be larger and longer than other trials, the quality of the data is only as good as the quality of the ratings and the raters who are responsible for measuring the degree of cognitive impairment exhibited by study participants. By using CQC, we can assure Alzheimer's Disease trial sponsors that regardless of rater turnover or the length of the study the results of a trial will reflect the activity of a drug, not bias or subtle errors caused by inconsistent ratings or less experienced raters," said Paul Gilbert, Chief Executive Officer of MedAvante. "Researchers have made great strides in understanding Alzhei
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SOURCE MedAvante, Inc.
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