Navigation Links
Measuring Blood Sugar With Light

WASHINGTON, Oct. 25, 2013 /PRNewswire-USNewswire/ -- One of the keys to healthful living with Type 1 and Type 2 diabetes is monitoring blood glucose (sugar) levels to ensure they remain at stable levels. People can easily and reliably do this at home using electronic devices that read sugar levels in a tiny drop of blood.


Now a team of German researchers has devised a novel, non-invasive way to make monitoring easier. Using infrared laser light applied on top of the skin, they measure sugar levels in the fluid in and under skin cells to read blood sugar levels. They describe their method in the current edition of Review of Scientific Instruments, which is produced by AIP Publishing.

"This opens the fantastic possibility that diabetes patients might be able to measure their glucose level without pricking and without test strips," said lead researcher, Werner Mantele, Ph.D. of Frankfurt's Institut für Biophysik, Johann Wolfgang Goethe-Universitat.

"Our goal is to devise an easier, more reliable and in the long-run, cheaper way to monitor blood glucose," he added.

The "Sweet Melody" of Glucose

Their new optical approach uses photoacoustic spectroscopy (PAS) to measure glucose by its mid-infrared absorption of light. A painless pulse of laser light applied externally to the skin is absorbed by glucose molecules and creates a measurable sound signature that Dr. Mäntele's team refers to as "the sweet melody of glucose." This signal enables researchers to detect glucose in skin fluids in seconds.

The data showing the skin cell glucose levels at one-hundredth of a millimeter beneath the skin is related to blood glucose levels, Mäntele said, but previous attempts to use PAS in this manner have been hampered by distortion related to changes of air pressure, temperature and humidity caused by the contact with living skin.

To overcome these constraints, the team devised a design innovation of an open, windowless cell architecture. While it is still experimental and would have to be tested and approved by regulatory agencies before becoming commercially available, the team continues to refine it.

In a close collaboration with an industry partner (Elté Sensoric:, they expect to have a small shoebox-sized device ready in three years, followed by a portable glucometer some years later.

The article, "Windowless ultrasound photoacoustic cell for in vivo mid-IR spectroscopy of human epidermis: Low interference by changes of air pressure, temperature, and humidity caused by skin contact opens the possibility for a non-invasive monitoring of glucose in the interstitial fluid" is authored by Miguel A. Pleitez, Tobias Lieblein, Alexander Bauer, Otto Hertzberg, Hermann von Lilienfeld-Toal, and Werner Mäntele. It appears in the journal Review of Scientific Instruments. See:  

Authors of this paper are affiliated with the Institut für Biophysik, Johann Wolfgang Goethe-Universität in Frankfurt/Main, Germany and Elté Sensoric in Gelnhausen, Germany.

The journal Review of Scientific Instruments, which is produced by AIP Publishing, presents innovation in instrumentation and methods across disciplines. See:

For More Information:
Jason Socrates Bardi
+1 240-535-4954

SOURCE AIP Publishing
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. New Evidence Published in Muscle and Nerve on Measuring 6-Minute Walk Distance in Duchenne Muscular Dystrophy
2. New Measuring TAPE Estimates Weight Of Kids Better Than Any Other Method
3. Problems Plague Medicares Method for Measuring Payment Errors
4. Particle Measuring Systems® Celebrates 40 Years of Leadership
5. Ventana licenses Gen-Probe IP for measuring ERG protein in prostate cancer patients
6. Blood Pressure Management Changed on Global Level with OSTARs 3SI Interpretive Blood Pressure Algorithm
7. Exosome Diagnostics Enters Collaboration Agreement with Lilly for Exosome Blood-Based Biomarker Discovery
8. Automated Telephone Calls Improve Blood Pressure Control
9. Diabetes Technology Society Outlines Potential Post-clearance Surveillance Program To Address Inaccuracy Of Blood Glucose Monitors
10. National Diabetes Volunteer Leadership Council (NDVLC) Urges FDA to Enforce Stringent Accuracy Standards for Blood Glucose Monitoring Systems
11. Simultaneous Applications Submitted to FDA and EMA for Siltuximab for the Treatment of Multicentric Castleman Disease, a Rare Blood Disorder
Post Your Comments:
(Date:6/23/2016)... , June 23, 2016 ... CAPR ), a biotechnology company focused on ... today announced that patient enrollment in its ongoing ... Duchenne) has exceeded 50% of its 24-patient target. ... in the third quarter of 2016, and to ...
(Date:6/23/2016)... , June 23, 2016 Bracket , a ... its next generation clinical outcomes platform, Bracket eCOA (SM) ... on June 26 – 30, 2016 in Philadelphia ... electronic Clinical Outcome Assessment product of its kind to fully ... Bracket eCOA 6.0 is a flexible platform for ...
(Date:6/23/2016)... RIDGE, Ill. and INDIANAPOLIS ... of students receiving a Lilly Diabetes Tomorrow,s Leaders Scholarship ... The 2016 scholarship winners, announced today online at ... to let type 1 diabetes stand in the way ... Diabetes has supported the Foundation,s scholarship program since 2012, ...
Breaking Medicine Technology:
(Date:6/25/2016)... ... ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter of ... too high can result in disappointment, perhaps even self-loathing. However, those who set the ... Research from reveals that behind the tendency to set low expectations ...
(Date:6/24/2016)... ... June 24, 2016 , ... Those who have experienced ... feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as a ... has released tools for healthy coping following a traumatic event. , Trauma sufferers tend ...
(Date:6/24/2016)... (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her son ... lash out at his family verbally and physically. , “When something upset him, he couldn’t ... would use it. He would throw rocks at my other children and say he was ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg ... Legal Elite. The attorneys chosen by their peers for this recognition are considered among ... Greenberg Traurig Shareholders received special honors as members of this year’s Legal Elite Hall ...
(Date:6/24/2016)... ... 24, 2016 , ... Comfort Keepers® of San Diego, CA is excited to ... Recovery® program to drive cancer patients to and from their cancer treatments. Comfort ... quality of life and ongoing independence. Getting to and from medical treatments is ...
Breaking Medicine News(10 mins):