Navigation Links
Mayo Researchers Help Discover Genetic Cause for Primary Biliary Cirrhosis
Date:5/27/2009

ROCHESTER, Minn., May 27 /PRNewswire-USNewswire/ -- Researchers have discovered a novel molecular path that predisposes patients to develop primary biliary cirrhosis, a disease that mainly affects women and slowly destroys their livers. Primary biliary cirrhosis has no known cause.

The finding, significant because it is a first step toward developing a targeted treatment and a cure, will be published in the June 11, 2009, issue of the New England Journal of Medicine.

"Now that we better understand the molecular basis of primary biliary cirrhosis, we can look for ways to specifically fix those elements," says Konstantinos Lazaridis, M.D., a Mayo Clinic hepatologist and a senior researcher in the study.

Currently, treatments for primary biliary cirrhosis can slow progression of the disease, which affects 1 in 2,500 Americans, 90 percent of them women. However, about half of patients do not respond to medical therapy. For some patients, a liver transplant cures the condition. But not all patients qualify for a transplant, and some transplant recipients experience a recurrence within five to 10 years.

The study was conducted at the University of Toronto using blood samples of patients collected at several medical centers in Canada and at Mayo Clinic's campus in Rochester, Minn., through its Primary Biliary Cirrhosis Genetic Epidemiology Research Resource. This resource comprises the biospecimens of hundreds of primary biliary cirrhosis patients and individuals who do not have the disease (controls) -- matched for age, sex, race and state of residence. Mayo Clinic and the University of Toronto are among the largest treatment centers in North America for
'/>"/>

SOURCE Mayo Clinic
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Tufts Medical Center Researchers Create a New Predictive Model for Age-related Macular Degeneration (AMD)
2. Karmanos Cancer Institute Researchers Study New Drug Combinations to Treat Childhood Leukemia
3. Karmanos Cancer Institute Researchers Present Breast Cancer Advancements at Conference
4. Researchers Discover Metabolite Linked to Aggressive Prostate Cancer
5. Why Wait for an Anti-Aging Drug? Researchers Interviewed on CBS-TVs 60 MINUTES Discover Longevinex(R) Nutriceutical Matrix Activates 9-Fold More Longevity Genes than Plain Resveratrol
6. Fertility Physicians of Northern California Researchers Test New Forms of Progesterone Medication for Luteal Support During IVF
7. Johns Hopkins University Researchers to Clinically Assess Rosetta Genomics miRview(TM) Squamous Assay
8. Researchers at Axial Biotech Develop a DNA Test for Scoliosis
9. K-State Researchers Awarded Nearly $1 Million to Test Remedies, Investigate Link Between E. Coli and Distillers Grains
10. Rapid Test for Pathogens Developed By K-State Researchers Could Be Used to Detect Diseases Used By Bioterrorists
11. Dallas Researchers Find Compression Stockings Improperly Used
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/6/2015)... 2015  EnteroMedics Inc. (NASDAQ: ETRM ), a ... to treat obesity, metabolic diseases, and other gastrointestinal disorders, ... of its previously announced underwritten public offering of 40,229,886 ... per unit. Canaccord Genuity was acting ... acting as co-manager for the offering. The ...
(Date:7/6/2015)... -- Impax Laboratories, Inc. (NASDAQ: IPXL ) announced today ... financial results on Monday, August 10, 2015, prior to ... will host a conference call and live webcast with ... August 10, 2015. The financial results and ... section of the Company,s Web site at http://investors.impaxlabs.com ...
(Date:7/6/2015)... 6, 2015  Nitin Tandon, M.D., UTHealth neurosurgeon ... Memorial Hermann Mischer Neuroscience Institute at the ... System technology into the skull of a 36-year-old ... seizures – the first time this procedure has ... "Epilepsy is a neurological condition that affects nearly ...
Breaking Medicine Technology:EnteroMedics Inc. Announces Termination of Public Offering of Common Stock and Warrants 2Impax to Report Second Quarter 2015 Results on August 10, 2015 2Memorial Hermann Successfully Completes System's First NeuroPace RNS System Procedure for Epilepsy Patient 2Memorial Hermann Successfully Completes System's First NeuroPace RNS System Procedure for Epilepsy Patient 3Memorial Hermann Successfully Completes System's First NeuroPace RNS System Procedure for Epilepsy Patient 4
... March 16 ExonHit Therapeutics,(Alternext: ALEHT) today reported ... by Institut Gustave Roussy, which describes the,identification of ... the,analysis of alternative RNA splicing [1]. Study data ... benign lesions, and alternative,transcripts determine the molecular characteristics ...
... WORTH, Texas, March 13 At the Health Industries ... Ph.D. and professor of public health and behavioral sciences ... Center,s School of Public Health, announced new findings ... economy. Specifically, unemployment and reduced spending on health ...
Cached Medicine Technology:ExonHit Reports Proof-of-Concept in Breast Cancer Diagnostic Using its SpliceArray(TM) Platform 2ExonHit Reports Proof-of-Concept in Breast Cancer Diagnostic Using its SpliceArray(TM) Platform 3ExonHit Reports Proof-of-Concept in Breast Cancer Diagnostic Using its SpliceArray(TM) Platform 4Unemployment, Health Care Spending Affect Mortality 2
(Date:7/7/2015)... , ... July 07, 2015 , ... Connexion Point is holding an onsite job fair ... held at 1769 Paragon Place, Suite 100, this upcoming Wednesday, July 8, and Thursday, July ... Connexion Point will be recruiting new applicants as well as holding onsite interviews. Interested ...
(Date:7/6/2015)... CA (PRWEB) , ... July 06, 2015 , ... For ... finding medical providers for personal injury victims. Throughout the company’s history the goal ... deliver the care victims need in their recovery. And while Doctors on Liens ...
(Date:7/6/2015)... ... July 06, 2015 , ... PristineHydro ( ... all acids, chemicals and impurities; it also properly mineralizes the water with electrolyte ... harmful contaminants.  These harmful contaminants are a byproduct of how the water is ...
(Date:7/6/2015)... ... 2015 , ... On June 22, 2015, Fox News in a report titled “ Female Hair Loss Needs ... 35 a quarter of all women in the U.S. will suffer from thinning hair or ... rarely discussed. One woman, a former beauty queen, who was interviewed for the report began ...
(Date:7/6/2015)... ... July 06, 2015 , ... ... year for aesthetic reasons, which is why liposuction regularly ranks among the top ... however, fat reduction has become more than a way to slim down a ...
Breaking Medicine News(10 mins):Health News:Connexion Point, a tech enabled healthcare services company, is holding on-site job fair July 8th and 9th to fill 400 positions at its new Memphis location 2Health News:Doctors on Liens Adds Transportation to Its Ever-Expanding Network 2Health News:Doctors on Liens Adds Transportation to Its Ever-Expanding Network 3Health News:Pristine Water Filters.com Offers The 1st Water Revival System That Re-Mineralizes Drinking Water and Eliminates All Impurities and Chemicals 2Health News:The Stigma of Female Hair Loss and Hair Restoration Solutions 2Health News:Learn How CoolSculpting® and Liposuction in Virginia Beach Help Military Members Stay the Course 2Health News:Learn How CoolSculpting® and Liposuction in Virginia Beach Help Military Members Stay the Course 3
... of World Where Cancer is Easily Detected and ... ... 6-year,cancer survivor and president and CEO of Susan G. Komen for the ... Labor and Pensions on the need for comprehensive legislation to,address the nation,s ...
... 2008 Wouldnt it be nice if our doctors ... particular medication" This question is important because research ... to respond to treatments, but inevitably, differences among groups ... about groups of patients may not apply to individuals ...
... Hill-Rom Holdings,Inc., (NYSE: HRC ) invites you ... president and chief executive officer, Hill-Rom. He will ... York on Wednesday, May 21,at 8:30 a.m. EDT., ... live presentation via the internet,link at http://www.hill-rom.com ...
... eDiets.com, Inc.,(Nasdaq: DIET ), leveraging the power of ... to everyone, today announced that it will,report results for ... U.S.,equity markets close on Tuesday, May 13, 2008., ... investors the,following day, Wednesday, May 14, beginning at 8:30 ...
... Inc. (Phyhealth) (Pink Sheets: PHYH), a developer of ... that Phyhealth Plan Corporation, a wholly-owned subsidiary of,Phyhealth, ... Tampa, Florida to,provide dental services for its Pilot ... of 2008., Mr. Robert Trinka, chairman and ...
... May 8 Biopure Corporation,(Nasdaq: BPUR ) ... has received new funding of approximately $3.4 million ... being granted,through the Department of Defense for a ... of Polytrauma Combat Casualties,with Brain Injury and Concomitant ...
Cached Medicine News:Health News:Susan G. Komen for the Cure's(R) Moddelmog Calls for Congress to Launch Colossal Cancer Crusade 2Health News:Susan G. Komen for the Cure's(R) Moddelmog Calls for Congress to Launch Colossal Cancer Crusade 3Health News:Improving anxiety treatment through the help of brain imaging: A potential future treatment strategy 2Health News:eDiets.com(R) to Report First Quarter 2008 Results on Tuesday, May 13, 2008 2Health News:Phyhealth Signs Agreement with Argus Dental to Provide Dental Services for Pilot HMO 2Health News:U.S. Navy Receives Funding for Further Development of Hemopure(R) 2Health News:U.S. Navy Receives Funding for Further Development of Hemopure(R) 3
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: