Navigation Links
Mayo Clinic Study Finds Further Association Between Diabetes and Pancreatic Cancer
Date:1/23/2008

Study's authors recruit patients for a clinical trial, another step in this ongoing research

ROCHESTER, Minn., Jan. 23 /PRNewswire-USNewswire/ -- A new Mayo Clinic study found that 40 percent of pancreatic cancer patients are diagnosed with diabetes prior to their pancreatic cancer diagnosis. The onset of diabetes appears to be many months (in some cases up to two years) prior to cancer diagnosis. This information provides researchers an important clue for earlier detection of pancreatic cancer. The study was published in this month's issue of Gastroenterology.

"Our previous studies have shown an association between recent diagnoses of diabetes and pancreatic cancer," says Suresh Chari, M.D., a Mayo Clinic gastroenterologist and the study's lead author. "We are now quite convinced that in most patients with pancreatic cancer the diabetes is caused by the cancer and not the other way around. Our next step is to identify a biomarker for pancreatic cancer-induced diabetes in order to screen patients with new-onset diabetes for early pancreatic cancer and provide surgical treatment as quickly as possible."

More than 33,000 people die each year from pancreatic cancer, the fourth-leading cause of cancer death in the United States. Patients with this cancer seldom exhibit disease-specific symptoms until the cancer is at an advanced stage and surgery is no longer an option. Therefore, fewer than 5 percent of pancreatic cancer patients survive five years after diagnosis.

This study reviewed the medical records of 736 patients with pancreatic cancer and 1,875 healthy individuals with fasting blood glucose data in their medical record. Dr. Chari's team found that 40 percent of pancreatic cancer patients were diagnosed with diabetes, while only 20 percent of the healthy individuals had fasting blood glucose levels in the diabetic range.

Type 2 diabetes is far more common than pancreatic cancer-induced diabetes. According to a previous study authored by Dr. Chari, only one in 125 patients over age 50 with new-onset diabetes will be diagnosed with pancreatic cancer. Dr. Chari's team continues work in identifying the differences between pancreatic cancer-induced diabetes and regular type 2 diabetes. The goal of the research is to cost-effectively screen for pancreatic cancer using a blood test that can identify individuals who have new-onset diabetes and are more likely to have pancreatic cancer. This will allow for earlier detection and increased opportunity for successful surgical treatment.

Other members of the Mayo Clinic research team included Cynthia Leibson, Ph.D., Kari Rabe, Lawrence Timmons, Jeanine Ransom, Mariza de Andrade, Ph.D., and Gloria Petersen, Ph.D.

As part of this ongoing research, a clinical trial studying the role of high resolution secretin-enhanced CT scan to diagnose early pancreatic cancer in patients at high risk for pancreatic cancer is currently in progress at Mayo Clinic in Rochester, Minn. Eligible participants must be 50 years or older, must have received a diagnosis of diabetes within the past two years, and must have at least one of the following: no family history of diabetes, abdominal discomfort or pain, weight loss, or elevated serum CA 19-9. For more information about eligibility requirements and the screening process for this study, please contact Theresa Nielson at (507) 538-2584.

To obtain the latest news releases from Mayo Clinic, go to http://www.mayoclinic.org/news. MayoClinic.com (http://www.mayoclinic.com) is available as a resource for your health stories.


'/>"/>
SOURCE Mayo Clinic
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
3. EpiCept Reports Expansion of Clinical Development For Licensed Cancer Compound
4. Auxilium Pharmaceuticals, Inc. Receives Clearance to Resume Clinical Trials for XIAFLEX(TM)
5. Romark Initiates Clinical Trial of Alinia(R) for Chronic Hepatitis C in the United States
6. The Multiple Myeloma Research Consortium (MMRC) and Proteolix Initiate Phase 2 Clinical Trial Investigating Carfilzomib for the Treatment of Multiple Myeloma
7. Millennium Initiates Clinical Trial to EVOLVE the Treatment of Patients with Newly Diagnosed Multiple Myeloma
8. Potential Safety Issue Identified in Ongoing Phase 2 Clinical Study of HCV-796
9. Clinical Trial Effectiveness: How Pharmas & Biotechs Save Cost with Savvy Investigator Management
10. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
11. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical Trial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/16/2017)... LOVELAND, Colo. , Jan. 16, 2017  Northern ... , is bringing advanced laser treatments to ... specialty clinic focuses solely on the removal of unwanted ... and fading for tattoo cover-ups. "Tattoos are ... out the way we hope they would," said ...
(Date:1/16/2017)... January 16, 2017 ... Product Type (Methyl, Ethyl, Hydroxyethyl, Hydroxypropyl, Carboxymethyl ... Beverages, Surface Coatings & Paints), Region - ... the market was valued at USD 4.51 ... reach USD 6.41 Billion by 2021, at ...
(Date:1/16/2017)... -- Transparency Market Research states that the leading ... a huge share of 43% in 2015. Apple Inc., F.Hoffmann-La ... overall market, grabbing the undivided attention of buyers with their ... strong product portfolio is expected to keep these companies in ... ...
Breaking Medicine Technology:
(Date:1/16/2017)... ... January 16, 2017 , ... ... Chief Executive Officer of the medical device company, effective immediately. , “This is ... “Kevin has a strong track record in medical device market development and ...
(Date:1/15/2017)... ... , ... Whole Health Supply, LLC is announcing the release of an updated version of their ... , The 2017 edition has wide jaws that will accommodate nails up to 4mm ... as diabetics. This handle is reinforced for extra strength when pressing down on dense nails ...
(Date:1/15/2017)... ... , ... Wondering where to go this Valentine's Day? Well, there is a ... romantic, lobster feast in the comfort of your own home. Lobster Gram is introducing ... be featured until February 15th, 2017. , Romantic Dinner one is Lobster Gram's ...
(Date:1/14/2017)... ... January 13, 2017 , ... ... Soul, incorporating a magnesium-rich Mediterranean diet may lower the risk of type 2 ... notes that the many health and wellness benefits linked to a Mediterranean diet ...
(Date:1/13/2017)... ... ... The 18th European Congress: Perspectives in Lung Cancer will be held in Madrid ... expertly designed to meet the educational needs of European oncology clinicians and researchers who ... Giorgio V. Scagliotti, Professor of Oncology at the University of Torino, and organized by ...
Breaking Medicine News(10 mins):