Navigation Links
Mayo Clinic Discovery May Help Diabetic Gastric Problem
Date:9/25/2008

ROCHESTER, Minn., Sept. 25 /PRNewswire-USNewswire/ -- Mayo Clinic researchers have found what may provide a solution to one of the more troubling complications of diabetes -- delayed gastric emptying or gastroparesis. The researchers showed in animal models that a red blood cell derivative increases production of a key molecule, normalizing the digestive process. The findings appear in the current online issue of the journal Gastroenterology (http://www.gastrojournal.org/).

Gastroparesis occurs when the stomach retains food for longer periods. When that food eventually passes into the small intestine, insulin is released. Because the passage of food out of the stomach becomes unpredictable, maintaining a proper blood glucose level -- critical for controlling diabetes -- also becomes difficult. Gastroparesis can cause pain, nausea, vomiting, stomach spasms and weight loss due to inadequate absorption of nutrients. The abnormally high blood glucose levels cause chemical changes in nerves and in pacemaker cells which regulate digestive processes in the gut, and damage blood vessels that carry oxygen and nutrients to cells.

"If these data are confirmed in humans, it may point toward a treatment for this difficult problem," says Gianrico Farrugia, M.D., Mayo Clinic gastroenterologist and senior author on the study. "Our goal is to normalize gastric emptying and therefore improve a patient's quality of life and glucose control."

Science Behind the Findings

Previous studies in animals and humans showed that two aspects of gastroparesis were: 1) loss of Kit, a marker for interstitial cells of Cajal (ICC), and 2) loss of expression of neuronal nitric oxide synthase (nNOS). ICC cells produce electrical signals that regulate muscle contraction in the digestive tract. nNOS generates nitric oxide, which transmits nerve impulses in the digestive tract. Both are important for normal fu
'/>"/>

SOURCE Mayo Clinic
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
3. EpiCept Reports Expansion of Clinical Development For Licensed Cancer Compound
4. Auxilium Pharmaceuticals, Inc. Receives Clearance to Resume Clinical Trials for XIAFLEX(TM)
5. Romark Initiates Clinical Trial of Alinia(R) for Chronic Hepatitis C in the United States
6. The Multiple Myeloma Research Consortium (MMRC) and Proteolix Initiate Phase 2 Clinical Trial Investigating Carfilzomib for the Treatment of Multiple Myeloma
7. Millennium Initiates Clinical Trial to EVOLVE the Treatment of Patients with Newly Diagnosed Multiple Myeloma
8. Potential Safety Issue Identified in Ongoing Phase 2 Clinical Study of HCV-796
9. Clinical Trial Effectiveness: How Pharmas & Biotechs Save Cost with Savvy Investigator Management
10. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
11. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical Trial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/1/2015)... June 1, 2015 Researchers from University Hospitals ... Reserve University School of Medicine will present data from ... novel combination treatment for cancer patients with advanced solid ... small cell lung cancer (SCLC), at the 51 st ... in Chicago . ...
(Date:6/1/2015)... LAVAL, QC , June 1, 2015 /CNW Telbec/ -  ... Laval and known under the « Équilibre, ... third quarter Ended on March 31, 2015. All dollar amounts ... Revenues for the third quarter of fiscal year 2015 ... % compared to revenues of $ 3,823,151 for the quarter ...
(Date:6/1/2015)... Women who took vitamin D and calcium supplements ... did not take the supplements, according to a study published ... of the European Menopause and Andropause Society. ... of the Women,s Health Initiative , one of the ... causes of death, disability and impaired quality of life in ...
Breaking Medicine Technology:UH Case Medical Center Experts to Present Data at 51st ASCO Annual Meeting 2UH Case Medical Center Experts to Present Data at 51st ASCO Annual Meeting 3Third Quarter results - Fiscal 2015 - Ergoresearch reports its results for the quarter ended March 31, 2015 2Third Quarter results - Fiscal 2015 - Ergoresearch reports its results for the quarter ended March 31, 2015 3Third Quarter results - Fiscal 2015 - Ergoresearch reports its results for the quarter ended March 31, 2015 4Vitamin D and Calcium Supplements Do Not Improve Menopausal Symptoms 2Vitamin D and Calcium Supplements Do Not Improve Menopausal Symptoms 3Vitamin D and Calcium Supplements Do Not Improve Menopausal Symptoms 4
... 17, 2010 The Medical Device practice at,MarketsandMarkets is pleased to announce ... India , China (BRIC) 2010 - 2015. , ... Browse in-depth TOC on Diagnostic ... (BRIC) 2010 - 2015 Market Report. Early buyers will receive 10%,customization of ...
... June 16 Tomorrow, the Food and Drug Administration (FDA) will hold a hearing ... an emergency contraceptive, or a new "Plan B." , ... http://photos.prnewswire.com/prnh/20080930/FRCLOGO ) , , , ... , , ...
Cached Medicine Technology:Diagnostic Imaging Markets in Brazil, Russia, India, China (BRIC) 2010 - 2015: MarketsandMarkets 2Diagnostic Imaging Markets in Brazil, Russia, India, China (BRIC) 2010 - 2015: MarketsandMarkets 3Diagnostic Imaging Markets in Brazil, Russia, India, China (BRIC) 2010 - 2015: MarketsandMarkets 4FRC Urges FDA to Reject New Abortion Drug Falsely Labeled as an Emergency Contraceptive 2
(Date:6/1/2015)... Garden City, NY (PRWEB) June 02, 2015 ... honors Lourinda Willey as a 2015-2016 ... Circle. She is recognized with this prestigious distinction for ... is the nation’s leading networking organization exclusively for professional ... operating Local Chapters. , "I’m pleased to present Lourinda ...
(Date:6/1/2015)... NY (PRWEB) June 02, 2015 ... Kathy Everette-Gaines as a 2015-2016 inductee into its ... recognized with this prestigious distinction for leadership in ... exclusively for professional women, boasting more than 700,000 ... “I’m pleased to welcome Kathy into this exceptional ...
(Date:6/1/2015)... Garden City, NY (PRWEB) June 02, 2015 ... honors Lenita F. Cornett, DSL, LSSBB (C), ... Inductee into its VIP Woman of the Year Circle. ... in the military. NAPW is the nation's leading networking ... members and over 200 operating Local Chapters. , “I'm ...
(Date:6/1/2015)... Carson Energy also announced they have selected AdvantaIRA ... Trust, LLC is the country’s largest self-directed IRA administrator. ... using IRA’s does 2 things:, 1. It gives investors ... there current cash position will not allow for participation. ... and their investors to be able to participate in ...
(Date:6/1/2015)... New York (PRWEB) June 01, 2015 ... http://www.testosteronelawsuithub.com/ ) has amended the Case Management Order ... AndroGel testosterone gel. The Amended Order which was ... Illinois on May 29, 2015, directs the parties to ... by August 10, 2015 that outlines parameters and the ...
Breaking Medicine News(10 mins):Health News:National Association of Professional Women Inducts Lourinda Willey, Owner and Principal of Lourinda R. Willey LLC, Into its VIP Professional Woman of the Year Circle 2Health News:The National Association of Professional Women Inducts Kathy Everette-Gaines, Community Relations Coordinator, Into its VIP Professional Woman of the Year Circle 2Health News:National Association of Professional Women Inducts Lenita F. Cornett, First Sergeant of the US Military, Into its VIP Professional Woman of the Year Circle 2Health News:Carson Energy Brings Oil Wells To IRAs 2Health News:Testosterone Lawsuit News: Federal Court Amends Order Governing AndroGel Bellwether Trial Selection 2Health News:Testosterone Lawsuit News: Federal Court Amends Order Governing AndroGel Bellwether Trial Selection 3Health News:Testosterone Lawsuit News: Federal Court Amends Order Governing AndroGel Bellwether Trial Selection 4
... Kong health authority had announced on Tuesday that the city ... HIV infections with 89 new cases reported// in the first ... Center for Health Protection under the Department of Health, which ... were related to sexual contact. Reviewing the AIDS situation in ...
... Shimla: The striking medicos, junior doctors and resident doctors ... College Tanda (Kangra),// took out a candle light procession ... central educational institutions. ,The striking medicos and doctors ... units of blood were collected and ran parallel OPDs. ...
... antidepressant Lexapro permitted by Food and Drug Administration, U.S.// ... FDA to sell escitalopram, a generic immitator of the oral ... drug are retained by the Forest Labs till March 2012 ... This copyright is illogical as per Teva. ,Lundbeck, ...
... that if the problem of people having HIV/AIDS as ... measures are not taken//. ,Launching the National ... the director general of Health Services said that the ... the population. "This is probably the reason TB is ...
... found that amino acid, l-cysteine can prevent oral cancers. ... cancers occur// in the mouth, pharynx and oesophagus. The ... results in a strong exposure of the upper digestive ... of Professor Mikko Salaspuro, University of Helsinki and Helsinki ...
... a recent study conducted by researchers at the Washington University ... States it was found// that regular exercise keeps Alzheimer’s at ... signs of the disease but now it is been disproved ... and found that balance problems and a weak handshake are ...
Cached Medicine News:Health News:Finnish research: Cysteine Chewing Gum as a cure for cancers of the mouth 2
The proximally modular S-ROM Total Hip System provides custom capability at non-custom prices and is competitive with conventional porous coated systems....
Quatroloc Revision Hip System...
Severe revision options for the knee and hip...
Severe revision options for the knee and hip...
Medicine Products: