Navigation Links
Mayo Clinic Discovery May Help Diabetic Gastric Problem
Date:9/25/2008

ROCHESTER, Minn., Sept. 25 /PRNewswire-USNewswire/ -- Mayo Clinic researchers have found what may provide a solution to one of the more troubling complications of diabetes -- delayed gastric emptying or gastroparesis. The researchers showed in animal models that a red blood cell derivative increases production of a key molecule, normalizing the digestive process. The findings appear in the current online issue of the journal Gastroenterology (http://www.gastrojournal.org/).

Gastroparesis occurs when the stomach retains food for longer periods. When that food eventually passes into the small intestine, insulin is released. Because the passage of food out of the stomach becomes unpredictable, maintaining a proper blood glucose level -- critical for controlling diabetes -- also becomes difficult. Gastroparesis can cause pain, nausea, vomiting, stomach spasms and weight loss due to inadequate absorption of nutrients. The abnormally high blood glucose levels cause chemical changes in nerves and in pacemaker cells which regulate digestive processes in the gut, and damage blood vessels that carry oxygen and nutrients to cells.

"If these data are confirmed in humans, it may point toward a treatment for this difficult problem," says Gianrico Farrugia, M.D., Mayo Clinic gastroenterologist and senior author on the study. "Our goal is to normalize gastric emptying and therefore improve a patient's quality of life and glucose control."

Science Behind the Findings

Previous studies in animals and humans showed that two aspects of gastroparesis were: 1) loss of Kit, a marker for interstitial cells of Cajal (ICC), and 2) loss of expression of neuronal nitric oxide synthase (nNOS). ICC cells produce electrical signals that regulate muscle contraction in the digestive tract. nNOS generates nitric oxide, which transmits nerve impulses in the digestive tract. Both are important for normal fu
'/>"/>

SOURCE Mayo Clinic
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
3. EpiCept Reports Expansion of Clinical Development For Licensed Cancer Compound
4. Auxilium Pharmaceuticals, Inc. Receives Clearance to Resume Clinical Trials for XIAFLEX(TM)
5. Romark Initiates Clinical Trial of Alinia(R) for Chronic Hepatitis C in the United States
6. The Multiple Myeloma Research Consortium (MMRC) and Proteolix Initiate Phase 2 Clinical Trial Investigating Carfilzomib for the Treatment of Multiple Myeloma
7. Millennium Initiates Clinical Trial to EVOLVE the Treatment of Patients with Newly Diagnosed Multiple Myeloma
8. Potential Safety Issue Identified in Ongoing Phase 2 Clinical Study of HCV-796
9. Clinical Trial Effectiveness: How Pharmas & Biotechs Save Cost with Savvy Investigator Management
10. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
11. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical Trial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)... British Columbia and MENLO PARK, Calif. ... (OTCQB: DMPI) ("DelMar" "the company") announced today a protocol ... trial had been filed with the U.S. Food and Drug ... 50mg/m 2 has been opened at three clinical trial ... company also confirmed that gross proceeds of US$2.9 million have ...
(Date:8/19/2014)... 2014 ,Weight Loss- Market Analysis, ... report provides comprehensive insights about phase III pipeline drugs ... of the report is to establish the understanding for ... across the different countries and regions. While the leading ... also provides details on the drug master filings across ...
(Date:8/18/2014)... Israel , Aug. 19, 2014 Immune ... Stockholm : "IMNP"), a biotechnology company, today announced ... its common stock on the NASDAQ Capital Market has been ... NASDAQ OMX Group. IMMUNE,s common stock is expected to begin ... trading on August 21, 2014 under the symbol IMNP. ...
Breaking Medicine Technology:DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 2DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 3DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 4DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 5DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 6DelMar Pharmaceuticals Provides Update on Glioblastoma Clinical Trial and Results of Warrant Tender Offer 7Weight Loss Market Analysis, Global API Manufacturers and Phase III Pipeline Assessment, 2014 2Weight Loss Market Analysis, Global API Manufacturers and Phase III Pipeline Assessment, 2014 3Weight Loss Market Analysis, Global API Manufacturers and Phase III Pipeline Assessment, 2014 4Immune Pharmaceuticals Announces Approval for Listing on the NASDAQ Capital Market 2Immune Pharmaceuticals Announces Approval for Listing on the NASDAQ Capital Market 3Immune Pharmaceuticals Announces Approval for Listing on the NASDAQ Capital Market 4
... Miami HEAT forward Juwan Howard and Basketball Hall of Famer ... for Adolescent Health and Medicine (SAHM) today to bring ... for Teens is a national awareness campaign designed to ... against serious and potentially life-threatening diseases. To ...
... 2011 /PRNewswire-Asia-FirstCall/ -- China-Biotics, Inc. (Nasdaq: CHBT ... of probiotics products in China, today reported its unaudited financial results ... year ended December 31, 2010. Third ... Net sales increased 39.0% y-o-y to $32.4 million; ...
Cached Medicine Technology:Miami HEAT Forward Juwan Howard and NBA Legend Bob Lanier Join Vaccines for Teens Educational Campaign to Urge Local Teens to Take Their Best Shot at Health 2Miami HEAT Forward Juwan Howard and NBA Legend Bob Lanier Join Vaccines for Teens Educational Campaign to Urge Local Teens to Take Their Best Shot at Health 3Miami HEAT Forward Juwan Howard and NBA Legend Bob Lanier Join Vaccines for Teens Educational Campaign to Urge Local Teens to Take Their Best Shot at Health 4Miami HEAT Forward Juwan Howard and NBA Legend Bob Lanier Join Vaccines for Teens Educational Campaign to Urge Local Teens to Take Their Best Shot at Health 5China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 2China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 3China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 4China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 5China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 6China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 7China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 8China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 9China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 10China-Biotics, Inc. Reports Record Quarterly Net Sales for the Third quarter of Fiscal Year 2011 11
(Date:8/20/2014)... 20, 2014 Hope For The Warriors® ... Celebration to be hosted in Washington, DC on Thursday, ... This signature event honors the courage of our wounded ... fallen. Proceeds from the Got Heart, Give Hope® Celebration ... dedicated to restoring a sense of self, restoring the ...
(Date:8/20/2014)... WA (PRWEB) August 20, 2014 “Have you ... an auto accident and personal injury lawyer serving the greater ... that incident? If so, then keep reading . , ... that individuals injured in an auto accident can use to ... Jones explains that a personal injury insurance claim will allow ...
(Date:8/20/2014)... The “Human Insulin Market by ... Premixed), Modern Human Insulin (Rapid Acting, Long Acting, ... Tresiba, Others) - Forecast to 2019” provides a ... current market trends,and strategies impacting the global human ... of the revenue and share analysis. , Browse ...
(Date:8/20/2014)... Burlingame, CA (PRWEB) August 20, 2014 ... publishers to speech-enable their websites and create a new ... users to consume content by listening to a narration ... in multiple reader genders and languages. Users can ... work, check social networks, while consuming content. ...
(Date:8/20/2014)... New York (PRWEB) August 20, 2014 Over ... the Global Bureau of Disease, low back pain is the ... the most common reasons for missed work. Americans spend at ... this pain. , Most cases of back pain are not ... mechanical (non-organic) origin. , For example, Pete, a busy accountant, ...
Breaking Medicine News(10 mins):Health News:Hope For The Warriors Announces Got Heart, Give Hope Celebration in Washington, DC 2Health News:Five Questions to Determine Who Qualifies for a Personal Injury Claim Recently Released by The Jones Firm in Recent Article 2Health News:Human Insulin Market by Product Types and Brand Worth $42 Billion by 2019 - New Report by MarketsandMarkets 2Health News:Human Insulin Market by Product Types and Brand Worth $42 Billion by 2019 - New Report by MarketsandMarkets 3Health News:Human Insulin Market by Product Types and Brand Worth $42 Billion by 2019 - New Report by MarketsandMarkets 4Health News:Mixberry Media, First To Offer Article Voice Narration with Integrated Audio Advertising 2Health News:Physical Therapists Learn to Relieve Low Back Pain 2
... diagnosis, treatment, researchers say , MONDAY, Oct. 5 (HealthDay News) ... on the diagnosis and treatment of one of the most ... new genes associated with head and neck cancer. , Previously, ... and neck cancer, which includes cancers of the mouth, nose, ...
... ... of growth charts/BMI, Children,s National pediatrician stresses the need for clear communication about seriousness ... ... explain the seriousness of a child being overweight may not be reaching the child,s ...
... Oct. 5 With the school season underway, New York ... to please organize blood drives at their schools, a process ... learning experience for both students and the surrounding community. , ... Brothers, a middle school educator. Now in its ...
... 5 Vocollect Healthcare Systems, Inc. and American ... contribute towards a more timely and unified Electronic ... This alliance interfaces the market,s top performing interactive ... software and EMR offering. , The ...
... In conjunction with its celebration of Case Management Week (Oct. ... the winner of its second annual $1,000 Patricia McCollom Scholarship ... of Fort Bragg, N.C. A case manager with the Army,s ... a highly qualified field of nominees who had either applied, ...
... than 7,000 people are diagnosed with head and neck cancer ... in death. These cancers include tumours of the mouth, ... to the sexually transmitted infection, HPV-16. Scientists at Liverpool ... to look for genes that indicated infection. The ...
Cached Medicine News:Health News:Gene Discovery May Advance Head and Neck Cancer Therapy 2Health News:Pediatrics: Doctors Must Find Better Ways to Talk To Parents about Childhood Obesity 2Health News:Pediatrics: Doctors Must Find Better Ways to Talk To Parents about Childhood Obesity 3Health News:Blood Drives Offer Lessons in Learning 2Health News:Blood Drives Offer Lessons in Learning 3Health News:American HealthTech and Vocollect Healthcare Systems Announce an Alliance to Deliver Unified Electronic Medical Records 2Health News:American HealthTech and Vocollect Healthcare Systems Announce an Alliance to Deliver Unified Electronic Medical Records 3Health News:CCMC Celebrates Case Management Week (Oct. 11-17) With Second Annual Patricia McCollom Scholarship 2Health News:DNA test could be key to targeting treatments for head and neck cancer 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: