Navigation Links
MatTek's EpiDerm In Vitro Tissues Headed for Validation in Europe
Date:10/8/2008

Acceptance Will Reduce Animal Use in Cosmetics and Chemicals Testing

ASHLAND, Mass., Oct. 8 /PRNewswire/ -- MatTek Corp. today announced that results of a recently completed US and European multi-laboratory "catch-up" validation study on MatTek's EpiDerm in vitro human skin tissue equivalent. The test results demonstrated the required sensitivity and specificity for EpiDerm to be accepted as a validated alternative to animal testing for determining human skin irritation by the European ECVAM Scientific Advisory Committee (ESAC).

Horst Spielmann, former Director, ZEBET (BfR), commenting on the skin irritation catch-up validation studies in AltTox.org, noted that the "take home message" from these new studies is that EpiDerm was not only successfully validated using just one endpoint (cytotoxicity -- MTT viability), but also that the EpiDerm classification test results met the criteria set by the validated skin irritation test method.

The results obtained for EpiDerm in the catch-up validation studies have been submitted to ECVAM for approval by the ECVAM Scientific Advisory Committee (ESAC) at its next meeting on Nov. 3-4, 2008.

Spielmann went on the say that it would be helpful in promoting the new in vitro skin irritation test in Europe if these catch-up validation results are taken into account at the OECD Expert Meeting being held in Berlin, Germany on October 20-21, 2008 to review the new Draft OECD Test Guideline on "In Vitro Skin Irritation: Human Skin Model." Inclusion of EpiDerm in this OECD Test Guideline will lead to EpiDerm acceptance in the very near future to meet the skin irritation testing requirements of the 6th amendment of the EU Cosmetics Directive and of the new EU Chemicals Directive (REACH).

John Sheasgreen, MatTek's President, added, "It is very gratifying to see MatTek's almost 15 years of in vitro human tissue equivalent development and production culminating in the full validation of these tissues a
'/>"/>

SOURCE MatTek Corp.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Oritavancin Demonstrates Potent and Rapid In Vitro Activity Against MRSA, VRE and Other Strains of Resistant Bacteria
2. Targanta Presents First Data Demonstrating In Vitro Activity and In Vivo Efficacy of Prodrugs in Osteomyelitis Models
3. Oritavancin Demonstrates Superior In Vitro Activity to Vancomycin and Metronidazole Against C. Difficile Bacteria
4. Georgia Reproductive Specialists Participates in Largest-Ever In Vitro Fertilization Clinical Trial in the World
5. Newly Published Study Shows OPKOs siRNA Bevasiranib Is Taken Up by Target Tissues in the Eye
6. NewCardio Announces Positive Results From Third Clinical Validation Study
7. M. D. Anderson to Initiate Clinical Validation Study on Rosetta Genomics MicroRNA-based Diagnostic Assay Identifying the Origin of Cancer Metastases
8. Michael J. Fox Foundation Awards $2.4 Million for Validation of Nine Promising Therapeutic Targets for Parkinsons Disease
9. ACRIN Study Endorses Virtual Colonoscopy - Validation for Colon CAD Software Maker Medicsight plc
10. NVA237 Phase II Results Presented at the European Respiratory Society Annual Meeting Show Promising Efficacy and Tolerability With Potentially Faster Onset Than Tiotropium
11. IDM Pharma Provides Update on Mifamurtide (L-MTP-PE) Regulatory Status Following September Meeting of European Committee for Medicinal Products for Human Use (CHMP)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... , Aug. 29, 2014  In part four ... leverage a hospital pharmacy as a strategic asset, ... practice leader for Cardinal Health,s Innovation Delivery Solutions business, ... can benefit both hospitals and patients. "Every ... one part of their job in a value-based healthcare ...
(Date:8/29/2014)... Aug. 29, 2014  Pacific Medical Data Solutions is ... website design . The main website, along with the ... company,s new services and content relevant to the medical ... streamlined design, viewers can now better understand how PMDS ... practices and create a more visible platform about medical ...
(Date:8/29/2014)... , August 29, 2014 Pixcelldata, ... collaboration software has announced a major new deal with ... by renowned pathology expert, Dr. Marius Nap . ... the 26th European Congress of Pathology which is taking ... ExCeL Arena, London where Pixcelldata ...
Breaking Medicine Technology:Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 2Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 3Five Ways Hospital Pharmacies Can Fulfill Their Quality Care Mission 4PMDS Announces New Website 2Pixcelldata Announces New Deal with Dutch Tele-Pathology Specialists eX-Path Ahead of ECP 2014 2
... , HOUSTON and DALLAS , Feb. ... the company,s management, medical staff, and employees, are making multiple monetary and ... in Haiti . , In response to the magnitude 7.0 quake, ... and over 195,000 awaiting medical attention, First Choice owner Jack Novak ...
... , VIENNA, Va. , Feb. 3 ... Geert Kersten , Chief Executive Officer, will be presenting at the ... Organization (BIO), the conference will take place February 8-9 ... presentation will be on Tuesday, February 9th , at ...
Cached Medicine Technology:First Choice ER to Donate Over $15,000 in Medical Supplies to Haitian Earthquake Victims 2CEL-SCI to Present at 12th Annual BIO CEO & Investor Conference 2
(Date:8/29/2014)... New York, New York (PRWEB) August 29, 2014 ... died from cardiac arrest following a series of dialysis ... that alleges her death was the result of ... Liebhard LLP reports. The family’s lawsuit, which was file ... 2014, claims that the use of the products resulted ...
(Date:8/29/2014)... Elk Grove Village, IL (PRWEB) August 29, 2014 ... welcomed Kathleen Baty, “The Safety Chick” who profiled ... including ETY•Kids® Safe-Listening Earphones from Etymotic Research. This ... school supply list, and Etymotic, an innovator of ... for young ears. Their ETY•Kids Safe-Listening Earphones, offered ...
(Date:8/29/2014)... HealthDay Reporter THURSDAY, Aug. 28, ... babies are getting the vaccines they need to protect ... More than 90 percent of children are getting ... polio; hepatitis B and chickenpox (varicella), according to the ... vaccination among children 19 to 35 months of age ...
(Date:8/29/2014)... U.S. Food and Drug Administration (FDA)-approved treatment for ... as effective at reducing fracture risk as other ... bone loss. With the use of wide- and ... carried out experiments at the U.S. Department of ... National Laboratory that revealed an additional mechanism underlying ...
(Date:8/29/2014)... adults who stay active by volunteering are getting more ... they are receiving a health boost! , ... at Baycrest Health Sciences and published online this week ... take a broad-brush look at all the available peer-reviewed ... for older adults. , Lead investigator Dr. Nicole Anderson, ...
Breaking Medicine News(10 mins):Health News:GranuFlo Lawsuit News: Family Alleges Woman’s Death Following Dialysis Was Caused by GranuFlo and NaturaLyte, Bernstein Liebhard LLP Reports 2Health News:GranuFlo Lawsuit News: Family Alleges Woman’s Death Following Dialysis Was Caused by GranuFlo and NaturaLyte, Bernstein Liebhard LLP Reports 3Health News:GranuFlo Lawsuit News: Family Alleges Woman’s Death Following Dialysis Was Caused by GranuFlo and NaturaLyte, Bernstein Liebhard LLP Reports 4Health News:The Today Show Features ETY•Kids® Safe-Listening Earphones by Etymotic 2Health News:Most U.S. Babies Get Their Vaccines: CDC 2Health News:Most U.S. Babies Get Their Vaccines: CDC 3Health News:Revealing a novel mode of action for an osteoporosis drug 2Health News:Evidence mounting that older adults who volunteer are happier, healthier 2
... July 12 (HealthDay News) -- Upward social mobility appears to ... who were born into poor or disadvantaged situations, according to ... and disadvantaged people are at increased risk for high blood ... researchers looked at health and socioeconomic data collected from 12,000 ...
... PITTSBURGH, July 11 A new method for scoring ... may help to predict their outcomes, according to researchers ... importantly, their findings, published in the early online version ... the severity categories rules out the potential for a ...
... By Randy Dotinga HealthDay Reporter , ... to secondhand smoke in their homes face a higher ... learning disorders, a new study finds. The ... children,s brains, and it doesn,t say how much smoke ...
... are increasingly implementing palliative care programs to help patients ... but a new University of Georgia study finds that ... palliative care services. "Most people will have some ... life, and many, especially frail elders, could benefit from ...
... Stroke is a leading cause of long-term disability and ... led by Gregory Bix, at Texas A&M College of Medicine, ... of the brain,s self-repair mechanisms to protect nerve cells and ... suggest that this approach could provide a nontoxic treatment for ...
... Older adults have to exercise more than younger adults in order ... examined how much exercise was needed to maintain or increase muscle ... ages 60 to 75. In the 16-week first phase of ... exercises (leg press, knee extensions and squats) three times a week. ...
Cached Medicine News:Health News:Pitt team finds way to classify post-cardiac arrest patients to better predict outcomes 2Health News:ADHD, Learning Issues May Be Linked to Secondhand Smoke 2Health News:Georgia hospitals lag in palliative care for the seriously ill, UGA study finds 2Health News:Georgia hospitals lag in palliative care for the seriously ill, UGA study finds 3Health News:JCI online early table of contents: July 11, 2011 2Health News:JCI online early table of contents: July 11, 2011 3Health News:JCI online early table of contents: July 11, 2011 4Health News:JCI online early table of contents: July 11, 2011 5Health News:JCI online early table of contents: July 11, 2011 6Health News:JCI online early table of contents: July 11, 2011 7Health News:JCI online early table of contents: July 11, 2011 8Health News:Older Adults Have to Exercise More to Maintain Muscle Size, Study Finds 2
Clinical micro clamps by Acland. Matte finish. It provides impressive security in use, both against slippage and against leakage due to controlled closing force and working grip surface....
Micro emulsifying needles, 18G....
Micro 2000, micro scissors micro 2000 supercut....
Yasargil clip applying forceps Mini. Stainless steel jaw....
Medicine Products: