Navigation Links
Mast Therapeutics Presents MST-188 Data at 7Th Annual Sickle Cell Disease Research and Educational Symposium
Date:4/17/2013

SAN DIEGO, April 17, 2013 /PRNewswire/ -- Mast Therapeutics, Inc. (NYSE MKT: MSTX) today announced that two posters for its lead product candidate, MST-188, were presented at the 7th Annual Sickle Cell Disease Research & Educational Symposium, currently underway in Miami.  

Brian M. Culley , Chief Executive Officer, said: "Increasing evidence suggests that transfusion of 'older' red blood cells (RBC) impairs clinical outcomes as a result of defects resulting from storage or age.  An NIH meta-analysis of 21 studies involving more than 400,000 patients reported that transfusion of older versus newer blood was associated with significantly increased risk of death.  Since older RBC aggregate more than younger RBC, we hypothesize that increased RBC aggregation following transfusion of older RBC or those with 'storage lesion' impairs blood flow in the microcirculation, where the majority of oxygen and nutrient exchange occur, thereby decreasing tissue perfusion and worsening outcomes." 

Mr. Culley continued: "The data presented today show that MST-188 reduced aggregation of both older and younger RBC, with a greater effect on older RBC.  If adverse clinical outcomes following transfusion are the result of increased RBC aggregation in the microcirculation, MST-188 may offer an option to improve the efficacy of transfusion.  We are conducting additional preclinical studies in this area, with the goal of helping to improve treatment options for the 4.5 million people who, in the U.S. alone, receive a transfusion each year." 

Poster Information:

  • The poster entitled "Is There a Role for a Rheologic Agent in Transfusion?" was presented by R. Martin Emanuele , Ph.D., Senior Vice President, Development
  • The poster entitled "Ev
    '/>"/>

SOURCE Mast Therapeutics, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Society for Brain Mapping and Therapeutics (SBMT) announce the formation of American Board of Brain Mapping, its 2013 award recipients and its Brain Mapping Day at the US Congress
2. Sorbent Therapeutics Initiates Phase 2b Clinical Trial of CLP-1001 for Treatment of Signs and Symptoms of Fluid Overload in Patients with Heart Failure
3. NewGen Therapeutics Presents Data on NT-113, A Novel Pan-ErbB Inhibitor, at American Association of Cancer Research
4. Sorrento Therapeutics, Inc. and IGDRASOL Announce Presentation on Non-Biologic Nanoparticle paclitaxel (NBN-Pac) Formulations for the Treatment of Solid Tumors at the Nanomedicine 2013 Meeting in Barcelona, Spain
5. Spencer Trask Congratulates InVivo Therapeutics on its Recent Approvals from the FDA
6. Zacks Industry Outlook Highlights: Eli Lilly, Novo Nordisk, Biogen, Amgen and Osiris Therapeutics
7. Adenosine Therapeutics Engages Needham & Company to Explore Strategic Options for Phase III Cardiac Stress Agent
8. Halozyme Therapeutics Names Matt Posard to Board of Directors
9. Mast Therapeutics Engages ESC Advisors To Identify Partnering Opportunities For MST-188
10. Cell Therapeutics Secures $15 Million Loan Financing Agreement
11. United Therapeutics Announces Receipt Of Second Complete Response Letter For Oral Treprostinil NDA
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... NxStage Medical, Inc. (NASDAQ: NXTM ... announced today that the U.S. Food and Drug ... perform hemodialysis overnight while the patient is at ... System One is the first and only hemodialysis ... Home nocturnal hemodialysis is an ...
(Date:12/22/2014)... 22, 2014 Research and Markets ... the "Investment Analysis of the US Medical ... http://photos.prnewswire.com/prnh/20130307/600769 ... medical device sector identifies the key trends and ... investments, and mergers and acquisitions. The ...
(Date:12/22/2014)... , Dec. 22, 2014 /PRNewswire/ -- RXi Pharmaceuticals ... company focused on discovering, developing and commercializing innovative ... technologies, today issued the following open letter to ... , Dr. Med. Sc. Dear RXi ... a number of inaccurate statements posted on certain ...
Breaking Medicine Technology:NxStage Receives FDA Clearance for Home Nocturnal Hemodialysis 2NxStage Receives FDA Clearance for Home Nocturnal Hemodialysis 3Investment Analysis of the US Medical Device Sector 2RXi Pharmaceuticals Issues Open Letter to Shareholders 2RXi Pharmaceuticals Issues Open Letter to Shareholders 3RXi Pharmaceuticals Issues Open Letter to Shareholders 4RXi Pharmaceuticals Issues Open Letter to Shareholders 5RXi Pharmaceuticals Issues Open Letter to Shareholders 6
... Dec. 3, 2010 Streamline Health Solutions, Inc. (Nasdaq: ... quarter fiscal year 2010 financial results for the period ended ... market closes. The Company will conduct a conference call and ... 2010 at 4:30 p.m. ET. Interested parties can ...
... 3, 2010 InfraReDx, Inc. , a medical ... announced that James E. Muller, M.D., founder and chief ... Canaccord Genuity Cardiovascular, Diabetes & Obesity Conference, to be ... San Francisco. The InfraReDx presentation is ...
Cached Medicine Technology:Streamline Health to Announce Third Quarter Fiscal Year 2010 Financial Results on Wednesday, December 8 2
(Date:12/26/2014)... December 26, 2014 Pentec Health, Inc. ... the state of Pennsylvania for 2014. The awards program, ... programs of its kind in the country. The program ... Pennsylvania Department of Community and Economic Development, the Pennsylvania ... and the Central Penn Business Journal. , ...
(Date:12/25/2014)... 26, 2014 This is a professional ... global Sterilizers industry with a focus on the Chinese ... status of the Sterilizers manufacturers and is a valuable ... interested in the industry. This report provides a basic ... manufacturing technology. In this part, the report presents the ...
(Date:12/25/2014)... 25, 2014 Product liability lawsuits filed ... recall ( http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward in ... Order issued in the U.S. District Court, Northern District ... an open conference on January 7, 2015, at the ... in West Palm Beach, Florida. The Conference is scheduled ...
(Date:12/25/2014)... December 25, 2014 The short film “Color ... created in honor of a true 9/11 hero, Welles Remy ... festivals including the 24 hours of Nuremberg International Short Film ... , Actress, screenwriter and director Luciana Lagana ... film together with her husband, Gregory Graham - ...
(Date:12/25/2014)... When head lice hits a home or school, parents and ... of it while keeping it from taking over the house ... solution right in their neighborhood: Lice Troopers . Expanding ... spectrum head lice screening and treatment services to families and ... Brickell, Coconut Grove, Kendall, Pinecrest and South Miami. , The ...
Breaking Medicine News(10 mins):Health News:Pentec Health Ranks Fourteenth on The Best Places to Work in PA for 2014 2Health News:Pentec Health Ranks Fourteenth on The Best Places to Work in PA for 2014 3Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 2Health News:Sterilizers Industry Global and Chinese Analysis for 2009-2019 Now Available at ReportsnReports.com 3Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 2Health News:The True 9/11 Hero Story “Color of Honor” Premieres in Germany and Bangladesh: Luciana Lagana Plays the Mother of the Lead and Co-Produces with Blaise Dolcemaschio. 3Health News:Coral Gables Florida Gets Ready to Be Lice-Free with Lice Troopers 2
... May 1, 2009, 7 am to 5 pm, ... of Michigan,s key stakeholders in disability benefits and workers, ... , is a group of volunteers from a ... promoting safer, healthier working lifestyles and preserving the employability ...
... TeamHealth Teleradiology has earned its second consecutive ... the company announced today."Organizations awarded this Gold Seal ... ensures innovative solutions are used for the most ... executive director of The Joint Commission,s Ambulatory Care ...
... elastography allows physicians to give a more accurate ... performed at Singapore General Hospital in Singapore. Breast ... the mechanical properties of tissues (relative stiffness) as ... backscatter of transmitted ultrasound waves through tissues. ...
... drainage of tubo ovarian abscesses help women avoid surgery, ... in Boston, MA. Tubo ovarian abscesses (TOAs) are an ... or ovaries. They can occur in patients with complicated ... , The study included 54 TOAs in 46 patients. ...
... as smoking and the direct impact on a senior,s health ... April 29 - May 3 in Chicago, IL. The ... past smokers and had never smoked. All three groups ... speed at which participants walked. After five years, it ...
... The following statement may be attributed to Jennifer ... from a veterinarian, Franck,s Pharmacy prepared medication that was ... Polo team. As soon as we learned of the ... led by an outside lawyer and, upon its conclusion, ...
Cached Medicine News:Health News:Workability in Michigan Summit to be Held May 1 2Health News:Joint Commission Awards TeamHealth Teleradiology Second Consecutive Gold Seal of Approval(TM) 2Health News:How late is too late to break bad habits? 2
... Anatomically Correct Design Is Unique Among All Lid ... Support The Lids Through An Anatomically Correct Arc ... With All Other Lid Speculums Which Pull Straight ... Tarsal Plate As They Open. Gentle Support ...
... Footplates Are Turned 90 Degrees To ... Blade While Incising Tissue. ,Special Mirror-Polished Double ... Penetration.,Pre-Set Blade Extension Settings Of 0.5mm, ... Full Extension.,1mm Wide Snub Nose Diamond ...
2.5V Halogen source, fiber-optic delivery, 2.5X magnification....
Pocket-sized instrument with 2.5X magnification....
Medicine Products: