Navigation Links
Mast Therapeutics Announces Positive Data In Model Of Heart Failure
Date:1/6/2014

SAN DIEGO, Jan. 6, 2014 /PRNewswire/ -- Mast Therapeutics, Inc. (NYSE MKT: MSTX) today announced that, in a placebo-controlled, nonclinical model of chronic heart failure, MST-188 demonstrated a statistically significant improvement in numerous parameters of heart function, including left ventricular ejection fraction and end-systolic volume, stroke volume and cardiac output.  Notably, a single two-hour infusion of MST-188 resulted in improvements that were significant immediately (at the end of MST-188 administration) and remained significant at one week (and, in some cases, at two weeks) after MST-188 administration. 

Hani N. Sabbah, Ph.D., Professor of Medicine & Director of Cardiovascular Research at Henry Ford Health System, said: "These data clearly show that MST-188 improves left ventricular ejection fraction and end-systolic volume, both of which are important indicators of long-term mortality and morbidity in chronic heart failure, with some effects lasting up to 2 weeks post-infusion.  The durability of response is very encouraging and merits clinical investigation."

Santosh Vetticaden, M.D., Ph.D., Chief Medical Officer of Mast Therapeutics, said: "Heart failure is an area of significant unmet medical need that accounts for over 1 million hospitalizations every year in the U.S. alone.  Although there have been modest improvements in treatment, heart failure remains associated with significant mortality and high rates of hospital admission and readmission.  We look forward to discussing these results with heart failure experts and potential partners and mapping our clinical development strategy in this exciting new indication." 

The Company has submitted data from this study for presentation at an upcoming medical conference and will provide an update on its plans for MST-188 in heart failure later in 2014. 

'/>"/>
SOURCE Mast Therapeutics, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Cell Therapeutics, Inc. (CTI) to Report First Quarter Financial Results on April 20
2. Faruqi & Faruqi, LLP Encourages Investors Who Suffered Substantial Losses Investing in Chelsea Therapeutics International, Ltd. to Contact the Firm
3. Argos Therapeutics Secures $25 million Series D Financing to Commence Phase 3 ADAPT Study in Patients with Metastatic Renal Cell Carcinoma (mRCC) in Mid-2012
4. Novelos Therapeutics Announces Successful Completion of First Cohort In Lung Cancer Trial With I-124-CLR1404 (LIGHT) Cancer-Targeted PET Imaging Agent at UW Carbone Cancer Center
5. Zacks Industry Outlook Highlights: Eli Lilly, Forest Labs, ViroPharma, Novartis and United Therapeutics
6. Oxford BioTherapeutics Appoints Senior Industry Leader to Head its New Clinical Development Operations in Basel, Switzerland
7. Nektar Therapeutics Reports Financial Results for the First Quarter of 2012
8. Cara Therapeutics Licenses Novel Kappa Opioid Agonist, CR845, to Chong Kun Dang Pharmaceutical Corporation For South Korean Market
9. Frost & Sullivan: High Uptake of New Drug Therapies and Aging Population Expansion Keep the U.S. Retinal Therapeutics Market Buoyant
10. Zenobia Therapeutics, Inc. And BioBlocks, Inc. Announce Sale Of A Joint Fragment Library Ideal For Screening By All Popular Methods
11. New Forecast Shows Global Protein Therapeutics Market to Reach $143.4 Billion by 2015
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... July 30, 2015 Mettler-Toledo International Inc. (NYSE: ... 2015.  Provided below are the highlights: , ... compared with the prior year. Reported sales decreased 4% ... quarter. , Net earnings per diluted share as ... prior-year period. Adjusted EPS was $2.80 , an ...
(Date:7/30/2015)... , July 30, 2015 IRIDEX Corporation ... release its second quarter 2015 financial results after the ... In conjunction with the release, the Company will host ... 5:00 p.m. Eastern Time on Thursday, August ... quarter and other business developments. Interested parties ...
(Date:7/30/2015)... 2015  Tandem Diabetes Care®, Inc. (NASDAQ: ... of the t:slim® and t:flex™ Insulin Pumps, today ... Agreements with Dexcom, Inc. to allow the integration ... Dexcom G5 and G6 continuous glucose monitoring ("CGM") ... platform with Dexcom,s future CGM systems is an ...
Breaking Medicine Technology:Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 2Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 3Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 4Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 5Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 6Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 7Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 8Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 9Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 10Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 11Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 12Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 13Mettler-Toledo International Inc. Reports Second Quarter 2015 Results 14IRIDEX Announces Second Quarter 2015 Conference Call and Release Date 2Tandem Diabetes Care Announces Development Agreement with Dexcom for Integration of Future Generation CGM Systems 2Tandem Diabetes Care Announces Development Agreement with Dexcom for Integration of Future Generation CGM Systems 3
... NEW YORK, Jan. 11, 2011 WebMD Health Corp. (Nasdaq: ... private placement of $400 million aggregate principal amount of 2.50% ... of notes pursuant to the exercise in full of the ... qualified institutional buyers pursuant to Rule 144A under the Securities ...
... /PRNewswire-Asia-FirstCall/ -- Dehaier Medical Systems Ltd. (Nasdaq: ... in the development, assembly, marketing and sale of medical ... that it will participate in the Arab Health Exhibition ... 2011 at the Dubai World Trade Centre in Dubai, ...
Cached Medicine Technology:WebMD Closes Offering of 2.50% Convertible Notes Due 2018 2Dehaier Medical Announces Participation in Arab Health 2011 2
(Date:7/31/2015)... ... July 31, 2015 , ... Healthpointe , a ... redesigned website at Healthpointe.net. The new website will feature a sleek and streamlined ... serves to provide smoother interactions between patients and the Healthpointe clinics and ensures ...
(Date:7/31/2015)... (PRWEB) , ... July 31, 2015 , ... ZH Healthcare ... OSEHRA 2015. , What is HITaaS? Health IT as a Service (HITaaS) is a ... software as a service (SaaS). , HITaaS manages all aspects of ...
(Date:7/31/2015)... ... 31, 2015 , ... EB Medicine, leading publisher of clinical ... pleased to announce that it has partnered with AgileMD to release Pediatric ... and Android smartphones and tablets. , “The April 2015 launch of our ...
(Date:7/31/2015)... VA (PRWEB) , ... July 31, 2015 , ... The ... U.S. Rep. Michael Burgess, MD, (R-Tex) presenting “What’s Next for Health Care: A View ... a physician and founder of the Congressional Health Caucus, Rep. Burgess has a special ...
(Date:7/31/2015)... ... July 31, 2015 , ... Super-Sod wants to participate in planning new home ... as the perfect fit for such a goal. Houzz is a social media ... is a dynamic site that spreads home and home garden design ideas when members ...
Breaking Medicine News(10 mins):Health News:Healthpointe Announces Newly Redesigned Website 2Health News:ZH Healthcare Unveils Health IT as a Service (HITaaS) at OSEHRA 2015 2Health News:ZH Healthcare Unveils Health IT as a Service (HITaaS) at OSEHRA 2015 3Health News:ZH Healthcare Unveils Health IT as a Service (HITaaS) at OSEHRA 2015 4Health News:EB Medicine Launches Mobile Application for Pediatric Emergency Medicine 2Health News:EB Medicine Launches Mobile Application for Pediatric Emergency Medicine 3Health News:Congressional Health Caucus Founder Rep. Michael Burgess, MD, to Speak at RBMA Fall Educational Conference 2Health News:Congressional Health Caucus Founder Rep. Michael Burgess, MD, to Speak at RBMA Fall Educational Conference 3Health News:Super-Sod Created a Landscape Profile on Houzz.com for Home Garden Design 2
... Don't get misled by the looks of freeze-dried fruits. ... that the antioxidant phytochemicals //that is present in fresh ... benefits of these dried fruits are assimilated easily into ... into this project, Gary Stoner, Ph.D., Professor and Chair ...
... a report it was found that Botswana has one of ... that about 81children //were abused in various forms between January ... the children were brutally beaten some were subjected to rape, ... not reported as the victim’s family opted for an out ...
... in protected and hygienic environments are more susceptible to ... ,Duke University Medical Center researchers investigated this ... to this case. They have identified why people in ... allergy and autoimmune diseases than do people in opposite ...
... Bioinformatics, a tool used to develop human disease research, now ... extremely //complex virus - the vaccinia virus, which is used ... Institute for Allergy & Immunology (LIAI). ,Researchers ... who have used it to successfully predict immune response to ...
... India open to acting in B'wood Sydney, Sabrina Houssami, ... Australia in the Miss World contest, says she is open ... non-Australian parentage to win the Miss Australia title last month, ... Lebanese father. ,Sabrina, who supports a charity called ...
... the medical journal Pediatrics, a single dose of chicken pox ... in schools. ,Dr. Sandra L. Snow and colleagues from ... outbreak of chicken pox at one of the schools. They ... had not suffered chicken and had taken the vaccination, and ...
Cached Medicine News:Health News:Protected Environment v/s Unprotected Affect Hygiene Health Immunity 2Health News:Protected Environment v/s Unprotected Affect Hygiene Health Immunity 3Health News:Protected Environment v/s Unprotected Affect Hygiene Health Immunity 4Health News:Bioinformatics Made a Boon In Immune Response Study - LIAI Finds 2Health News:Bioinformatics Made a Boon In Immune Response Study - LIAI Finds 3
...
... features an advanced design that accommodates both ... gives surgeons the flexibility to easily customize ... is built-in to every aspect of the ... Secure-Twist anti-migration system to the screw options ...
... is designed to meet the clinical challenges ... attached locking mechanism and the choice of ... variable angle screws for ease of implantation ... plate system allows the surgeon the versatility ...
... Revolutions start with small things. ... is one of the trailblazers of ... reflecting the,trend towards ever smaller access ... the operation site. ,The HiLAN XS ...
Medicine Products: