Navigation Links
Marital Status Doesn't Affect Lung Cancer Survival

But Other Differences Warrant Further Study, Researchers Say

DURHAM, N.C., Dec. 28 /PRNewswire/ -- Contrary to previous studies, married patients with lung cancer do not have longer survival, according to analysis of an extensive Mayo Clinic database in the December issue of "The Oncologist."

However, the results suggest some other potentially important differences among patient subgroups -- including the possibility that married patients receive a more aggressive approach to lung cancer treatment, write Dr. Aminah Jatoi and colleagues.

The researchers analyzed data on nearly 5,900 patients from a Mayo Clinic database of patients with non-small cell lung cancer (NSCLC), the most common type of lung cancer. The database included information on a wide range of factors, including cancer stage, cancer treatment, and other factors affecting prognosis.

The study also included information on marital status: 76 percent of the patients were married (average age, 65 years), four percent single, seven percent divorced, and twelve percent widowed (average age, 73 years). The researchers analyzed the data to see if there was any relationship between the patients' marital status at the time their cancer was diagnosed and their survival outcomes.

Initial analysis found no significant differences in survival among the different marital status groups. This remained true after adjustment for important prognostic factors, including age, tumor stage, and smoking. The results were in contrast to previous studies suggesting that married patients with lung cancer tended to have longer survival.

However, exploratory analyses found some significant differences in lung cancer treatment by marital status. Widowed and divorced patients received less aggressive treatment for cancer, which in some cases seemed to lead to shorter survival times. Survival was also shorter for patients in certain subgroups -- for example, widowed patients with stage IA lung cancer (the least advanced stage).

Some aspects of quality of life also differed among marital groups. Divorced patients had greater financial concerns than patients in the other groups, while married and widowed patients had greater spirituality and better social support.

Smaller, less well-controlled studies have reported longer survival for married patients with lung cancer. The extensive Mayo Clinic NSCLC database provided an opportunity to re-evaluate the relationship between marriage and lung cancer survival.

The findings show no differences in survival based on marital status. "Nonetheless, marital status at times appeared to have influenced whether or not a patient received certain types of cancer therapy," the researchers write.

The subgroup analyses also suggest other differences in lung cancer treatment and quality of life that are worthy of further exploration, Dr. Jatoi and coauthors believe. They conclude, "Thus, health care providers

should continue to remain sensitive to the importance of human bonds as they care for patients with NSCLC."

The new article, entitled "Does Marital Status Impact Survival and Quality of Life in Patients with Non-Small Cell Lung Cancer? Observations from the Mayo Clinic Lung Cancer Cohort," is available online at and in print in the December issue of "The Oncologist."

About AlphaMed Press

AlphaMed Press publishes the internationally renowned journals "Stem Cells" and "The Oncologist." "Stem Cells," now in its 25th year, is the oldest and one of the world's top-tier peer-reviewed monthly journals in the fast-paced area of stem cells and regenerative medicine. "The Oncologist," in its 12th year, is a premier peer-reviewed monthly journal dedicated to physicians entrusted with the care of cancer patients. Its highly acclaimed CME program, "The Oncologist CME Online," has awarded more than 32,800 AMA PRA Category 1 Credits(TM). View AlphaMed Press journals at

Contact: George Kendall: 919-680-0011,

SOURCE AlphaMed Press
Copyright©2007 PR Newswire.
All rights reserved

Related medicine technology :

1. Alfacell Updates Status of ONCONASE(R) Phase III Clinical Program
2. US FDA Grants Orphan Drug Status to Immtechs Pafuramidine for Treatment of African Sleeping Sickness
3. Chinese SFDA Grants Immtech Fast Track Status
4. Imaging Diagnostic Systems Updates PMA Filing Status for the New CT Laser Breast Imaging System
5. Nuvelo Begins Phase 2 Trial and Receives Fast Track Status for Alfimeprase in Patients With Acute Ischemic Stroke
6. Antheras A-001 Receives Orphan Drug Status for the Prevention of Acute Chest Syndrome in Patients With Sickle Cell Disease
7. Sexual Function Affected by Stem Cell Transplant According to Long-Term Study
8. Aegerion Pharmaceuticals, Inc. Presents Final Results of Phase II Clinical Trials for AEGR-733 at Drugs Affecting Lipid Metabolism (DALM) 2007 Conference
9. Surface Logix Presents Positive Phase 1 Repeat-Dose Trial Data on SLx-4090 at The 16th International Symposium on Drugs Affecting Lipid Metabolism
10. Most Women With HIV and Their Health Care Providers Have Not Discussed How HIV Might Affect Them Differently Than Men
11. Clinical Trial Participation Unaffected by Disclosure of Investigators Financial Stake, Food and Drug Law Journal Article Finds
Post Your Comments:
(Date:11/26/2015)... India , November 26, 2015 ... --> adds ... Report" and "Investigation Report on China ... and 2021 forecasts data and information ... . ...
(Date:11/26/2015)... , November 26, 2015 ... the addition of the  "2016 Future ... European Cell Surface Marker Testing Market: ...  report to their offering.  --> ... addition of the  "2016 Future Horizons ...
(Date:11/25/2015)... , Nov. 25, 2015  The American Academy ... Gynecologists (ACOG), and the March of Dimes cheered ... Protecting Our Infants Act of 2015 (S.799), ... of newborns born exposed to drugs, such as ... bill,s introduction, all three organizations have worked together ...
Breaking Medicine Technology:
(Date:11/30/2015)... INDIANAPOLIS, IN (PRWEB) , ... November 30, 2015 ... ... provider of carrier-grade software solutions and services which empower organizations through communication analytics, ... users, helping them effectively monitor and manage their service quality. , Proteus® ...
(Date:11/29/2015)... ... November 29, 2015 , ... NewsWatch featured X-wing as part of its ... Amanda Forstrom, a technology expert and special reporter for NewsWatch, conducted the review and ... future. , It’s the future because flying cars are about to become a reality. ...
(Date:11/29/2015)... ... November 29, 2015 , ... Effective immediately, every single ... addition starting on Black Friday Target is offering a “Buy One Scrub Set, Get ... a rare opportunity to purchase IguanaMed at a discounted price. , IguanaMed’s ...
(Date:11/28/2015)... ... ... Beginning November 30th at 6:00 a.m. EST until 11:59 p.m. EST, customers ... up to 20% off orders $80 or more to free gifts with purchases, there will ... As a competitive e-commerce website for skin care and cosmetic needs, customers will save on ...
(Date:11/27/2015)... CO (PRWEB) , ... November 27, 2015 , ... According ... cities are not changing the way that they are handling security in light of ... police and security presence in an attempt to stop an attack from reaching U.S. ...
Breaking Medicine News(10 mins):