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Major Repligen (Nasdaq: RGEN) Shareholder Files Amended 13D
Date:3/5/2012

lew from Chicago to Boston to attend the meeting in person, only to be informed upon my arrival that the meeting would be of very limited duration.

As I have repeatedly stated, I am simply trying to make sure that the voice of the shareholders of Repligen is heard at the board level, and that Repligen's policies are modified in matters of compensation, stockholder ownership of board members and officers, etc. to enhance the alignment of the Board's interests with those of its shareholders. 

As for submitting candidates to the Nominating and Governing Committee, it should not be necessary for me to go through that procedure. Considering my extensive holdings in Repligen, obviously it is in my interest that any candidate I would propose will have the qualities, skills and characteristics to serve as a constructive director.  Frankly, the non-transparent nature of the committee's deliberations and the short window for providing information to the committee strikes me as ways Repligen is seeking to entrench its existing Directors and officers.  The deadline to provide candidates in my case serves to limit my ability to select the best candidate(s).  I would therefore ask that the deadline for my submission be extended for 90 days, or waived entirety.  I request that the Committee pledges to work with me in good faith so that the person or persons I select are recommended by the Committee.  Please respond by March, 15 2012 to my proposal.

I have been a patient, long-term investor and supporter of Repligen.  As you know, I own nearly 10% of Repligen and my discussions with several other substantial holders of stock indicate broad support for additional involvement of shareholders in the Board, including new board members.  As we have repeatedly discussed, I would like to work collaboratively with the Board, and not at cross-purposes. However, I reserve my right under the Company's by-laws to take whatever actio
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SOURCE Ronald L. Chez, Inc.
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