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Major Repligen (Nasdaq: RGEN) Shareholder Files Amended 13D
Date:3/5/2012

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PF5CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(d) or 2(e) 6CITIZENSHIP OR PLACE OF ORGANIZATION

United States of AmericaNUMBER OF SHARES7SOLE VOTING POWER

 2,815,631BENEFICIALLY
OWNED BY
EACH
REPORTING
PERSON
WITH8SHARED VOTING POWER

09SOLE DISPOSITIVE POWER

010SHARED DISPOSITIVE POWER

2,815,63111AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

2,815,63112CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES 13PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

9.2%(1)14TYPE OF REPORTING PERSON (See Instructions)

IN 

 

 

 _________________________________

(1)
Based upon 30,714,757 shares of the Issuer's common stock issued and outstanding as of October 31, 2011, as reported on the Issuer's Form 10-Q for the quarterly period ended September 30, 2011.Pursuant to Rule 13d-2 of Regulation 13D-G of the General Rules and Regulations under the Securities Exchange Act of 1934, as amended, the undersigned, Ronald L. Chez (the "Reporting Person") hereby amends his statement on Schedule 13D dated January 30, 2007, as amended by Amendment No. 1 to Schedule 13D dated July 13, 2007; Amendment No. 2 to Schedule 13D dated October 20, 2008; Amendment No. 3 to Schedule 13D dated June 20, 2011; Amendment No. 4 to Schedule 13D dated July 13, 2011; and Amendment No. 5 to Schedule 13D dated August 15, 2011; and Amendment No. 6 to Schedule 13D dated January 25, 2012
(collectively, the "Schedule 13D").  This Statement constitutes Amendment No. 7 to the Schedule 13D.  Unless otherwise indicated herein, there are no material changes to the information set forth in the Schedule 13D.

Item 4.
Purpose of Transaction
is hereby amended by adding thereto the following:On March 5, 2012, the Reportin
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SOURCE Ronald L. Chez, Inc.
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