Navigation Links
MEI Pharma Initiates Phase II Clinical Trial Of Pracinostat In Refractory Myelodysplastic Syndrome
Date:1/14/2014

SAN DIEGO, Jan. 14, 2014 /PRNewswire/ -- MEI Pharma, Inc. (Nasdaq: MEIP), an oncology company focused on the clinical development of novel therapies for cancer, announced today that the first patient has been dosed in a Phase II clinical trial of Pracinostat, the Company's investigational oral histone deacetylase (HDAC) inhibitor, in patients with myelodysplastic syndrome (MDS) who either failed to respond or maintain a response to a hypomethylating agent (HMA) alone.

(Logo: http://photos.prnewswire.com/prnh/20120628/LA32362LOGO)

"We are very excited about getting this study underway," said Robert D. Mass, MD, Chief Medical Officer of MEI Pharma. "This represents the third in a series of Phase II clinical trials we are conducting with Pracinostat in combination with HMAs in an attempt to establish the clinical benefit of selectively combining two epigenetic modifiers. The primary objective in this refractory MDS trial is to determine if the addition of Pracinostat to Vidaza® or Dacogen® can improve clinical responses or rescue previous responses achieved with a HMA alone. We look forward to reporting preliminary data from all three Phase II trials of Pracinostat later this year."

This two-stage trial of Pracinostat is expected to enroll up to a total of 76 patients into two groups: 1) patients who have had disease progression or have relapsed following a clinical response to either Vidaza or Dacogen therapy and 2) patients with stable disease who failed to respond to their initial HMA therapy. If at any time two or more responses are observed in the first 29 patients of each group, that group will continue to enroll an additional nine patients in the second stage, for a total of up to 38 evaluable patien
'/>"/>

SOURCE MEI Pharma, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Study Finds Utilizing Integrated Medical and Pharmacy Data Improves Ability to Forecast Use of High-cost Specialty Treatments
2. Report Presents a Framework for Successful New Oncology Product Launches in the Pharmaceutical Sector
3. WuXi PharmaTech Files 2011 Annual Report on Form 20-F
4. Savient Pharmaceuticals to Hold First Quarter 2012 Financial Results Conference Call on Wednesday, May 9, 2012
5. Pharmaceutical Industry Service Company Awarded The UKs Most Prestigious Business Accolade in Recognition of Outstanding Achievement in International Trade
6. Academy of Managed Care Pharmacy (AMCP) Installs 2012-2013 Board of Directors
7. Auxilium Pharmaceuticals to Present at the Deutsche Bank 37th Annual Healthcare Conference
8. Simcere Pharmaceutical Group to Announce First Quarter 2012 Financial Results on Wednesday, May 9, 2012
9. Nouveau Life Pharmaceuticals (HRID) Contracts with U.S. Manufacturer to Produce New Female Supplement
10. Thomson Reuters Launches New Mobile Oncology Decision Support Solution for R&D Pharmaceutical Leaders
11. Amgen to Acquire Mustafa Nevzat, a Leading Privately Held Turkish Pharmaceutical Company
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/14/2014)... Animal Emergency Critical Care, a LifeCentre partner practice, located at 165 ... the first in Loudoun County to receive ... Susan M. Barnes , Medical Director, is a well-seasoned veterinarian of ... Taylor , are avid scuba divers. "As altitude skiers and hikers, ...
(Date:1/14/2014)... Jan. 14, 2014 NineSigma , Inc., the ... Innovation Leadership Summit , May 14-16, 2014 at ... Cleveland Ohio . This is ... committed to breakthrough achievements through open innovation. Participants will ...
(Date:1/14/2014)... January 14, 2014 Equashield ( ... hazardous drugs, today announced that it has achieved ... year.   Equashield,s closed systems reduce ... nurses and other medical professionals who prepare and ...
Breaking Medicine Technology:Hyperbaric Veterinary Medicine (hvm) Announces Animal Emergency Critical Care Installs A Small Animal Hyperbaric Chamber 2Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 2Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 3Expect the Unexpected from Leading Global Innovators at NineSigma Leadership Summit, Sharing Winning Strategies to Advance Innovation 4Equashield's Sales Grow by 60% in 2013 2
... consumer protection program provided by the National Association of ... on quality of care when buying medications online. Similarly, ... "know your medicine, know your pharmacist," highlights the pharmacist,s ... The AWARxE program aims to educate patients on the ...
... VIEW, Calif., Oct. 12 Based on its ... & Sullivan presents Xenemetrix, Inc. with the 2010 ... (Logo:   http://photos.prnewswire.com/prnh/20081117/FSLOGO ) ... leading designer, manufacturer, and distributor of Energy Dispersive ...
Cached Medicine Technology:AWARxE Recognizes American Pharmacists Month 2Frost & Sullivan Global Product Line Strategy of the Year Award Presented to Xenemetrix 2Frost & Sullivan Global Product Line Strategy of the Year Award Presented to Xenemetrix 3
(Date:4/24/2014)... Changes in managing patients before, during and after ... reduced readmission rates, according to researchers who led a ... The practice, called enhanced recovery, is easier on patients ... bowel evacuation that are typically prescribed. After surgery, patients ... as possible, leading to faster recoveries. , Among findings ...
(Date:4/24/2014)... aspects, the corresponding terminology, and the relevance of ... in publications on randomized controlled trials (RCTs). This ... German Institute for Quality and Efficiency in Health ... final report. , Together with external experts, IQWiG ... glioblastoma, lung cancer, malignant melanoma, and pancreatic cancer. ...
(Date:4/24/2014)... was the first in the world to discover a ... the jaw. , Ameloblastoma is an odontogenic tumour with ... most often found in the posterior of the lower ... tissue deficiencies in the jaws as well as loss ... the need for surgery and the recurrence of ameloblastoma, ...
(Date:4/24/2014)... 2009 the influenza pH1N1 virus caused the first flu ... in May 2009 and killed more than 50 people ... Finns mainly during flu epidemics (winter/spring seasons). , ... serious complicated illnesses. World Health Organization has recommended Tamiflu ... The disadvantage of this drug is that it targets ...
(Date:4/23/2014)... Pregnant immigrants from Sub-Saharan Africa, Latin America and ... according to new research from St. Michael,s Hospital. ... British Journal of Obstetrics and Gynaecology , assessed ... immigrants and native-born women in six high-immigration countries ... (Catalonia and Valencia) and the United States (California, ...
Breaking Medicine News(10 mins):Health News:New approach for surgery patients cuts hospital stays and costs 2Health News:New approach for surgery patients cuts hospital stays and costs 3Health News:Palliation is rarely a topic in studies on advanced cancer 2Health News:Palliation is rarely a topic in studies on advanced cancer 3Health News:Pregnancy complications may be more common in immigrants from certain regions 2
... seniors , , DETROIT, Dec. ... and chiropractic services to its Flexible Health Options Benefit for ... list of services to promote wellness encourages Medicare beneficiaries to ... in their wallets. , , ...
... Seele,Founder/CEO of The Balm In Gilead, joined Rick Warren, pastor ... community leaders at a,Civic Forum on Global Health for a ... Lady Laura Bush,s leadership in addressing,HIV around the globe. , ... first State of the Union address that President Bush pledged,to ...
... center focused,on improving the quality of life of children ... led by a world-renowned researcher whose,concepts and tools are ... The Siskin Center for Child and Family Research joins ... organization focused,on education, outreach and support for children with ...
... 3, 2008 Joined by actress Maggie,Gyllenhaal, Duracell(R) today announced the ... in age from six to 15 years old --,at an event ... best known for her role in "The Dark Knight," to promote ... of powering,up a gift for the first time to those most ...
... WALTHAM, Mass., Dec. 3 Decision Resources, one ... on pharmaceutical and,healthcare issues, finds that the diagnosis ... extremely low and will remain low through 2012,particularly ... disease,will account for approximately 70 percent of the ...
... sense approach to dieting. , ... San Francisco, CA ... source for comparing the most valuable Internet services, is launching ... a free guide filled with useful advice for those embarking on ...
Cached Medicine News:Health News:UPDATE: HAP Expands Medicare Advantage Options to Include Acupuncture and Chiropractic Services 2Health News:UPDATE: HAP Expands Medicare Advantage Options to Include Acupuncture and Chiropractic Services 3Health News:The Balm In Gilead Joins Saddleback Church in Thanking President Bush for His Leadership on Addressing HIV and AIDS Around the World 2Health News:Siskin Center for Child and Family Research to Focus on Early Childhood Development and Special Education 2Health News:Siskin Center for Child and Family Research to Focus on Early Childhood Development and Special Education 3Health News:Siskin Center for Child and Family Research to Focus on Early Childhood Development and Special Education 4Health News:Duracell and Actress Maggie Gyllenhaal Announce Winners of 'Power A Smile' Casting Call After Nationwide Search for Five Child Holiday Ambassadors 2Health News:Duracell and Actress Maggie Gyllenhaal Announce Winners of 'Power A Smile' Casting Call After Nationwide Search for Five Child Holiday Ambassadors 3Health News:Diagnosis and Drug Treatment of Alzheimer's Disease in China is Low and Will Remain Low Through 2012 2Health News:Diagnosis and Drug Treatment of Alzheimer's Disease in China is Low and Will Remain Low Through 2012 3Health News:NextAdvisor.com Launches "Lose the Weight this Year: A Common Sense Dieter's Guide" 2
Pediatric model. Spring-controlled spread of blades with locking mechanism. Dull finish. Blades: 11 mm....
Fenestrated blades with screw-controlled spread. Dull finish. Blades: 15 mm....
Designed for use with foster enucleation snare (E3670). Package of 12 stainless steel wires. Overall length 5.3 inches....
IOL explanation snare for foldable lenses. Snare bisects lens for easy removal. Easy thumb activation. Replacement snares available E3526....
Medicine Products: