Navigation Links
MEI Pharma Initiates Phase II Clinical Trial Of Pracinostat In Refractory Myelodysplastic Syndrome
Date:1/14/2014

SAN DIEGO, Jan. 14, 2014 /PRNewswire/ -- MEI Pharma, Inc. (Nasdaq: MEIP), an oncology company focused on the clinical development of novel therapies for cancer, announced today that the first patient has been dosed in a Phase II clinical trial of Pracinostat, the Company's investigational oral histone deacetylase (HDAC) inhibitor, in patients with myelodysplastic syndrome (MDS) who either failed to respond or maintain a response to a hypomethylating agent (HMA) alone.

(Logo: http://photos.prnewswire.com/prnh/20120628/LA32362LOGO)

"We are very excited about getting this study underway," said Robert D. Mass, MD, Chief Medical Officer of MEI Pharma. "This represents the third in a series of Phase II clinical trials we are conducting with Pracinostat in combination with HMAs in an attempt to establish the clinical benefit of selectively combining two epigenetic modifiers. The primary objective in this refractory MDS trial is to determine if the addition of Pracinostat to Vidaza® or Dacogen® can improve clinical responses or rescue previous responses achieved with a HMA alone. We look forward to reporting preliminary data from all three Phase II trials of Pracinostat later this year."

This two-stage trial of Pracinostat is expected to enroll up to a total of 76 patients into two groups: 1) patients who have had disease progression or have relapsed following a clinical response to either Vidaza or Dacogen therapy and 2) patients with stable disease who failed to respond to their initial HMA therapy. If at any time two or more responses are observed in the first 29 patients of each group, that group will continue to enroll an additional nine patients in the second stage, for a total of up to 38 evaluable patien
'/>"/>

SOURCE MEI Pharma, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Study Finds Utilizing Integrated Medical and Pharmacy Data Improves Ability to Forecast Use of High-cost Specialty Treatments
2. Report Presents a Framework for Successful New Oncology Product Launches in the Pharmaceutical Sector
3. WuXi PharmaTech Files 2011 Annual Report on Form 20-F
4. Savient Pharmaceuticals to Hold First Quarter 2012 Financial Results Conference Call on Wednesday, May 9, 2012
5. Pharmaceutical Industry Service Company Awarded The UKs Most Prestigious Business Accolade in Recognition of Outstanding Achievement in International Trade
6. Academy of Managed Care Pharmacy (AMCP) Installs 2012-2013 Board of Directors
7. Auxilium Pharmaceuticals to Present at the Deutsche Bank 37th Annual Healthcare Conference
8. Simcere Pharmaceutical Group to Announce First Quarter 2012 Financial Results on Wednesday, May 9, 2012
9. Nouveau Life Pharmaceuticals (HRID) Contracts with U.S. Manufacturer to Produce New Female Supplement
10. Thomson Reuters Launches New Mobile Oncology Decision Support Solution for R&D Pharmaceutical Leaders
11. Amgen to Acquire Mustafa Nevzat, a Leading Privately Held Turkish Pharmaceutical Company
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/17/2014)... , Sept. 17, 2014 Germany Gynecological ... GlobalData,s new report, "Germany Gynecological Devices Market ... the Germany Gynecological Devices market. The report provides ... units) and average prices (in US dollars) within ... Devices (Micro-inserts) and Mechanical Sterilization Devices (Tubal Clips ...
(Date:9/17/2014)... NEW YORK , Sept. 17, 2014 ... of PDL BioPharma, Inc. ("PDL BioPharma" or the "Company") ... Robert S. Willoughby at rswilloughby@pomlaw.com or ... PDL BioPharma and certain of its officers and/or directors ... Exchange Act of 1934.  On September ...
(Date:9/17/2014)... 17, 2014 Bronstein, Gewirtz & Grossman, LLC ... the securities of PDL BioPharma, Inc. ("PDL BioPharma" or ... investors are advised to contact Peretz Bronstein ... at info@bgandg.com or 212-697-6484. The ... its executives violated federal securities laws. On ...
Breaking Medicine Technology:Germany Gynecological Devices Market Outlook to 2020 2Germany Gynecological Devices Market Outlook to 2020 3SHAREHOLDER ALERT: Pomerantz Law Firm Investigates Claims On Behalf of Investors of PDL BioPharma, Inc. - PDLI 2Shareholder Alert: Bronstein, Gewirtz & Grossman, LLC Investigates claims on behalf of Investors of PDL BioPharma, Inc. --PDLI 2
(Date:9/18/2014)... September 18, 2014 For many people, tomato ... an online food delivery service provider, gives it a new ... Tomato Basil soup is a nod to this culinary classic—with ... a tangy tomato base, then Spoonful of Comfort's chefs stir ... A flashback to childhood has never tasted better. , ...
(Date:9/18/2014)... Computer Resources of America, Inc. (CRA), ... York City, has been awarded a contract to provide ... with stores in over 150 countries. The services will ... being the retailer’s dispatch arm handling all IT support ... Chief Executive Officer of CRA said, “We are excited ...
(Date:9/18/2014)... Albany, NY (PRWEB) September 18, 2014 ... foods, which have special functions of adjusting human ... etc., have won great popularity with a variety ... of health food in China reached RMB187.4 billion, ... of 22.1% during 2006-2013. , View Full Report ...
(Date:9/18/2014)... Boston, MA (PRWEB) September 18, 2014 ... train its team and surgeon partners in Less ... to joining SpineFrontier, Tamara authored an extensive education ... holds a Masters in Science in Organizational Leadership, ... multiple industries for eleven years. Bringing her to ...
(Date:9/18/2014)... September 18, 2014 Dr. Suzaunna Clark, ... 1- sometimes, inner beauty has to be seen to ... be acknowledged in order to be used. Together, both ... shows the world how to do both. ... Coaching using the Healing Hearts system, which provides professional ...
Breaking Medicine News(10 mins):Health News:An Old Classic Brings New Soup Delivery Options to Spoonful of Comfort 2Health News:CRA Awarded Managed Support Contract for Global Retailer 2Health News:China Health Food Industry Size 2014 Market Analysis, Growth, Trends and Forecast Report 2017: MarketResearchReports.biz 2Health News:China Health Food Industry Size 2014 Market Analysis, Growth, Trends and Forecast Report 2017: MarketResearchReports.biz 3Health News:China Health Food Industry Size 2014 Market Analysis, Growth, Trends and Forecast Report 2017: MarketResearchReports.biz 4Health News:SpineFrontier Inc. Makes Bold Move to Expand Its Internal Training Team to Collaborate With The LESSociety’s Less Exposure Surgery® University To Educate Surgeons. 2Health News:Suzaunna-Where Life! Happens Announces the Launch of Healing Hearts 2Health News:Suzaunna-Where Life! Happens Announces the Launch of Healing Hearts 3
... seek answers to questions of motivation and self-actualization. "Make ... Honaman employs lessons learned in his career working with ... to help others direct their energies and develop their ... "Make It Happen" that personal branding is the process ...
... 20 Hooper Holmes, Inc. (Amex: HH ... Health and Wellness Division, Christopher J. Behling, will be ... Colloquium on Tuesday, March 3, 2009 at 9:00 a.m. ... Regency at Penn,s Landing in Philadelphia, Pennsylvania. Mr. Behling,s ...
... Faced with news of increasing layoffs, straining economic times, ... hiring is based on looks, millions of American women ... them a competitive edge in the workplace. In a ... of 18 and 64 compiled by the ASPS, many ...
... 20 The Niwano Peace Foundation announced Friday it will ... Baguma Byamugisha, an Anglican priest of Uganda, in recognition of ... people living with HIV/AIDS.An award presentation ceremony will take place ... award certificate, Rev. Byamugisha will receive a medal and 20 ...
... York, NY, February 20, 2009 Although widespread Prostate-Specific-Antigen ... there a point of diminishing returns? In a study ... Journal of Urology , researchers found that in a ... years old or older and had a PSA below ...
... in chronic obstructive lung disease (COPD) themselves increase ... days of full, asymptomatic recoverybad news for patients ... progression of the disease. , "This concept ... for the analysis of clinical trial data and ...
Cached Medicine News:Health News:Business Strategist Applies Corporate Experience to Self-Help: 'Make It Happen' 2Health News:Hooper Holmes to Present at the Ninth Population Health and Disease Management Colloquium 2Health News:Hooper Holmes to Present at the Ninth Population Health and Disease Management Colloquium 3Health News:In Today's Economy, Women In The Workforce Link Cosmetic Chicago Plastic Surgery To Success 2Health News:In Today's Economy, Women In The Workforce Link Cosmetic Chicago Plastic Surgery To Success 3Health News:Rev. Byamugisha of Uganda to Receive Niwano Peace Prize 2Health News:When should prostate-specific antigen testing be stopped? 2Health News:Exacerbations in COPD: One thing leads to another 2Health News:Exacerbations in COPD: One thing leads to another 3
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: