Navigation Links
MDS Patients on Five-Day Vidaza(R) Dosing Schedules Achieve Transfusion Independence Consistent with Seven-day Schedule
Date:12/11/2007

ematological malignancies and in solid tumors. These key growth control genes can be re-expressed in cancer cells when DNA hypermethylation is reversed by Vidaza and/or inappropriate histone deacetylation is inhibited by MGCD0103. The epigenetic approach to cancer therapy is that rather than using molecules that kill both normal and tumor cells, the silenced genes are reactivated through targeted epigenetic therapy, re-establishing the cancer cell's natural mechanisms to control abnormal growth.

About Myelodysplastic Syndromes (MDS)

Myelodysplastic syndromes, or MDS, are a group of diseases in which the bone marrow does not function normally, resulting in the production of malformed or immature blood cells. MDS affects approximately 40,000-50,000 people in the United States and 75,000-85,000 patients in Europe. The majority of patients with higher-risk MDS eventually experience bone marrow failure. Up to 50 percent of MDS patients succumb to complications, such as infection or bleeding, before progressing to acute myeloid leukemia (AML). MDS patients have a median survival of four months to five years depending on risk stratification. Higher-risk patients have a median survival of five to 14 months and typically do not achieve positive outcomes when treated with current conventional care regimens (CCR) including basic supportive care, chemotherapy, and Ara-C. Alleviation of disease-related complications, including transfusion requirements and hematologic improvement are key treatment goals in lower-risk MDS. Altering the natural history of disease is one of the most important treatment goals in higher-risk MDS.

Important Safety Information

Vidaza is contraindicated in patients with a known hypersensitivity to Vidaza or mannitol and in patients with advanced malignant hepatic tumors.

In clinical studies, the most commonly occurring adverse reactions by SC route were nausea (70.5%), anemia (69.5%), thrombocytopenia (65.5%), vomiting
'/>"/>

SOURCE Pharmion Corporation
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
3. Millennium Initiates Clinical Trial to EVOLVE the Treatment of Patients with Newly Diagnosed Multiple Myeloma
4. Allos Therapeutics Initiates Study of PDX in Patients with Cutaneous T-Cell Lymphoma
5. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
6. Sixty-One Percent of Newly Diagnosed Parkinsons Disease Patients Do Not Receive Any Drug Treatment in the First Year of Diagnosis
7. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
8. Many Heart Attack Patients Dont Get Best Emergency Treatment
9. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
10. Phase 2a Multi-Dose Study Initiated by MedImmune in Patients With Asthma to Further Expand Anti-Interleukin-9 Program
11. MedImmune Initiates Phase 2a Multi-Dose Study in Patients with Asthma
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/26/2015)... May 26, 2015   Generational Equity , a ... is pleased to announce the acquisition of its client, ... Spokane, Washington , by Mi-Med Supply ... April 30, 2015. Peaks & Plains ... region, selling medical, incontinent, nutritional, patient care, and housekeeping ...
(Date:5/26/2015)...  Juniper Pharmaceuticals, Inc. (Nasdaq: JNP ) ("the ... therapeutics that address unmet medical needs in women,s ... will present at the Marcum MicroCap Conference ... 4:00 PM EDTLocation: , The Grand Hyatt, New ... under  ,Investor, or  click here The ...
(Date:5/26/2015)... ® Technologies, Inc., the leader in non-invasive, accelerated orthodontic ... to continued demand from orthodontists and patients for safe, ... locations in the U.S. and Canada ... the only FDA-cleared Class II medical device that has ... much as 50 percent.  A recent ...
Breaking Medicine Technology:Generational Equity Announces the Acquisition of Peaks & Plains Inc. by Mi-Med Supply 2Juniper Pharmaceuticals to Present at Investor Conference on May 28, 2015 2OrthoAccel Technologies Continues Trajectory of Accelerated Growth with Over 2,500 Practice Locations 2OrthoAccel Technologies Continues Trajectory of Accelerated Growth with Over 2,500 Practice Locations 3
(Date:5/26/2015)... May 27, 2015 Carey Danis ... testosterone gel lawsuit . The suit pertains to ... suit was filed in late April 2015, and a ... an Illinois federal court in mid-May.¹ , Testosterone gel ... for the Northern District of Illinois. The multidistrict litigation ...
(Date:5/26/2015)... ANGELES (PRWEB) May 27, 2015 Readers ... processes may find help in author Chester Litvin ... Psychoconduction : Litvin’s Code” (published by Trafford Publishing). , ... new approach for stimulating the brain. This book will ... to reeducate their sensory brain cells . He ...
(Date:5/26/2015)... Ohio (PRWEB) May 26, 2015 Mr. Gould ... since 2010, will start working together this week to ensure ... accomplished career in healthcare executive leadership and strategy. Gary ... prior to the hiring of Mr. Cochran. The Board of ... will complement the improvement strategies implemented over the past few ...
(Date:5/26/2015)... Neeta Pai was diagnosed with HHT in ... four of which landed her in the emergency room ... Though she still struggles with anemia, iron deficiency and ... to increasing HHT awareness and garnering support for the ... could have prevented all the heartbreak and trauma my ...
(Date:5/26/2015)... 2015 Sexual harassment and sexual assault are ... best known for creating opportunities in women's athletics, it is ... response and prevention. In a recent episode of SCI ... explains what Title IX means for university administrators dealing ... of this issue to protect students. , In the last ...
Breaking Medicine News(10 mins):Health News:Carey Danis & Lowe Comments on Recently Filed Testosterone Gel Lawsuit 2Health News:Chester Litvin’s New Book Offers ‘Tune-Up’ for Brain Cells 2Health News:Chester Litvin’s New Book Offers ‘Tune-Up’ for Brain Cells 3Health News:Rochester Woman Brings Awareness to Genetic Disease 2Health News:Paul Greene Explores Title IX and College Sports on SCI TV 2Health News:Paul Greene Explores Title IX and College Sports on SCI TV 3
... wonder hormone which is discovered around 1994 which has the ... burns calories// and performs other crucial physiological activities. ... through which Leptin carries out these metabolic activities were not ... of Medicine of Yeshiva University have identifies the mode in ...
... Geography professor of Kansas State University, Doug Goodin, makes ... land use and land cover //changes on human health ... combines remote sensing with other types of data, to ... with other scientists he recently discussed this subject at ...
... 22,000 U.S men for a good 14 years has revealed ... on the body weight has an impact in cutting down ... B. Rimm, co-author of the study, said "Even though erectile ... has become clear that heart disease and ED share many ...
... HIV positive patients and ensure welfare measures to them, ... K G Balakrishnan said today. ,Delivering the ... committees to protect the rights of HIV/AIDS patients and ... in this regard was under the consideration of the ...
... medical services functioning smoothly and the institute's director P ... attending to patients - a day after the Delhi ... ,While health services normalised in AIIMS after doctors, on ... agitation last evening following the court order, the Director ...
... In NSW, daycare centers are planning to phase out junk ... set up by the Health Department to counter childhood ... soft drinks, even as they were being sent to dieticians. ... in two to five-year-olds, is the biggest study of its ...
Cached Medicine News:Health News:How Does Leptin Work? 2Health News:Satellite Imagery to monitor the Social Impact Of Geographical Changes 2
...
...
...
Open blade speculum designed for both temporal and superior approach ocular surgery. Thumb screw adjusting mechanism. Manufactured in titanium....
Medicine Products: