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MAQUET Cardiovascular Announces Results Of The IABP-SHOCK II Trial Of Intra-aortic Balloon Counterpulsation Therapy In Cardiogenic Shock Patients
Date:8/26/2012

MUNICH and WAYNE, N.J., Aug. 27, 2012 /PRNewswire/ -- MAQUET Cardiovascular LLC, the market leader in intra-aortic balloon counterpulsation therapy, today announced 30-day results from the large, randomized, multicenter IABP- SHOCK II ("SHOCK II") clinical trial in patients with acute myocardial infarction (AMI) who were in cardiogenic shock and undergoing early revascularization. The findings showed that use of intra-aortic balloon counterpulsation (IABC) therapy was associated with an observed improvement in all-cause mortality at 30 days, but the trial did not meet the pre-specified 12 percent improvement in survival endpoint compared with standard medical therapy. In the trial, IABC therapy was shown to be safe without any increase in complications compared to the control group.  The findings were presented in the Hot Line II: Late-Breaking Trials on Interventions session during the European Society of Cardiology (ESC) Congress 2012 in Munich. 

"Patients in cardiogenic shock are critically ill and require aggressive treatment measures," said Marc Cohen, M.D., chief of the division of cardiology at Newark Beth Israel Medical Center in Newark, N.J., and professor of medicine at the Mount Sinai School of Medicine in New York.  "The results of the SHOCK II trial demonstrated unparalleled safety with IABC therapy in this patient population, and I believe it would be premature, without further exploration of the data, to determine which patients are best served with IABC therapy."

He added, "Previous clinical trials in other patient populations, including those undergoing high-risk percutaneous coronary intervention [PCI], have shown that the benefits of IABC therapy can be seen beyond 30 days.  It is important that we wait and assess the six-month and 12-month mortality data from IABP-SHOCK II before making definitive conclusions about the use of IABC therapy in cardiogenic shock patients."

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SOURCE MAQUET Cardiovascular LLC
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