Navigation Links
MAP Pharmaceuticals to Present Data on LEVADEX® at the 15th Congress of the International Headache Society
Date:6/23/2011

EX (MAP0004, Orally Inhaled DHE) in Healthy Volunteers — Results from 3 Clinical Studies: Pooled analyses assessing the clinical pharmacokinetics of LEVADEX and its primary metabolite across three recent clinical studies show consistent pharmacokinetic results and rapid absorption via the pulmonary route of administration.

Abstract #: A-345-0001-00616

Poster presentations will be available on the Publications section of MAP Pharmaceuticals' website at http://www.mappharma.com by the conclusion of the Congress.

About LEVADEX® LEVADEX is an investigational drug for migraine. The Company has submitted a New Drug Application to the U.S. Food and Drug Administration for the potential acute treatment of migraine in adults. In the clinical trial, patients administered LEVADEX themselves using the proprietary TEMPO® inhaler.  LEVADEX contains a novel formulation of dihydroergotamine (DHE).  LEVADEX was evaluated in the efficacy portion of FREEDOM-301, MAP Pharmaceuticals' Phase 3 pivotal trial, which included 395 patients in the LEVADEX arm and 397 patients in the placebo arm.  In the Phase 3 trial, patients taking LEVADEX had statistically significant improvement at two hours compared to patients on placebo for all four co-primary endpoints:

  • Pain relief: 58.7 percent of patients who received LEVADEX compared with 34.5 percent for placebo (p<0.0001);
  • Phonophobia free: 52.9 percent of patients who received LEVADEX compared with 33.8 percent for placebo (p<0.0001);
  • Photophobia free: 46.6 percent of patients who received LEVADEX compared with 27.2 percent for placebo (p<0.0001); and
  • Nausea free: 67.1 percent of patients who received LEVADEX compared with 58.7 percent for placebo (p=0.02).

  • The most common adverse event reported was medication aftertaste at six percent versus two percent for placebo.  The next most commo
    '/>"/>

    SOURCE MAP Pharmaceuticals, Inc.
    Copyright©2010 PR Newswire.
    All rights reserved

    Page: 1 2 3 4

    Related medicine technology :

    1. Auxilium Pharmaceuticals, Inc. Receives Clearance to Resume Clinical Trials for XIAFLEX(TM)
    2. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
    3. Solvay Pharmaceuticals, Inc. and Wyeth Pharmaceuticals Announce Receipt of an FDA Action Letter for Bifeprunox, an Investigational Treatment for Schizophrenia
    4. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
    5. WallSt.net (www.wallst.net) Updates the Investment Community Through an All-New Interview With RegeneRx Biopharmaceuticals CEO
    6. Quark Pharmaceuticals, Inc. Presented Positive Preclinical Results of Systemic RNAi Compound for Acute Renal Failure (ARF)
    7. Peregrine Pharmaceuticals Doses First Patient in Cotara(R) Phase II Brain Cancer Trial In India
    8. Nabi Biopharmaceuticals Announces Second Quarter 2007 Financial Results
    9. Access Pharmaceuticals Provides Update on Clinical Development Plan of ProLindac
    10. Quark Pharmaceuticals Extends Research Agreement with State University of New York for Proprietary siRNA Compounds for Acute Hearing Loss
    11. Acura Pharmaceuticals, Inc. Secures Financing to Fund Pivotal Phase III Clinical Trial for Lead Aversion(R) Technology Product Candidate
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:7/30/2015)... July 30, 2015 IRIDEX Corporation (NASDAQ: ... second quarter 2015 financial results after the market closes ... with the release, the Company will host a conference ... Eastern Time on Thursday, August 6, 2015 ... other business developments. Interested parties may access ...
    (Date:7/30/2015)... 30, 2015  Unichem Pharmaceuticals ( USA ... Hydrochlorothiazide tablets 25 mg 1000-count bottle to the consumer ... measure due to the identification of a Clopidogrel tablet ... The risk associated with mistakenly taking a Clopidogrel ... probability of experiencing Clopidogrel,s side effects which include bleeding ...
    (Date:7/30/2015)... 2015 Tianyin Pharmaceutical Inc. (NYSE Amex: ... in the patented biopharmaceutical, modernized traditional Chinese medicine (mTCM), ... regarding the notice it received on May 21, 2015 ... the Company was below certain of the Exchange,s continued ... 1101 of the NYSE MKT Company Guide, due to ...
    Breaking Medicine Technology:IRIDEX Announces Second Quarter 2015 Conference Call and Release Date 2Unichem Pharmaceuticals (USA), Inc. Issues a Voluntary Nationwide Recall of Hydrochlorothiazide Tablets Due to the Potential Presence of Foreign Tablets 2TPI Provides Update Regarding Non-Compliance with NYSE MKT Continued Listing Requirements 2
    ...   Unigene Laboratories, Inc. (OTCBB: UGNE), today announced ... position of Chief Financial Officer. In this newly created position, ... company,s executive leadership team and lead the strategic direction ... Mr. Moskowitz joins Unigene after spending the previous ...
    ... 2012 Reportlinker.com announces that a new ... catalogue: Vaccines - ... This market research report package offers ... situation, trends and future outlook for vaccines ...
    Cached Medicine Technology:Unigene Appoints David Moskowitz as Chief Financial Officer 2Unigene Appoints David Moskowitz as Chief Financial Officer 3Unigene Appoints David Moskowitz as Chief Financial Officer 4Unigene Appoints David Moskowitz as Chief Financial Officer 5Vaccines - Asia 2
    (Date:7/30/2015)... ... July 30, 2015 , ... Zaca ... on the go. With no water needed, the refreshing berry-flavored tablets are the ... to get the natural ingredients that may help with body detoxification, protection and ...
    (Date:7/30/2015)... , ... July 30, 2015 , ... ... Mid-Atlantic region, is the recipient of three awards in the Service Industry Advertising ... programs created for Choptank Transport, KRM Development Corporation and University of Maryland Shore ...
    (Date:7/30/2015)... ... 30, 2015 , ... Well-known San Diego AC, plumbing and ... cost service and repair companies. For 35 years, they have grown both their ... to meet the demands of the changing technological environment. , To ...
    (Date:7/30/2015)... ... July 30, 2015 , ... 24/7 Care At Home, a ... San Bernardino, recently announced that the Centers for Medicare and Medicaid (CMS) have awarded ... health care providers. 24/7 Care At Home’s agency is one of three top Orange ...
    (Date:7/30/2015)... ... July 30, 2015 , ... The ... Institute Scholar Program. In partnership with Patient Experience Institute, these offerings reinforce the ... on the front lines and throughout the experience movement, and provide information and ...
    Breaking Medicine News(10 mins):Health News:Zaca Life Introduces Recovery Chewable Packets with Setria® Glutathione and Sustamine® L-Alanyl-L-Glutamine 2Health News:Zaca Life Introduces Recovery Chewable Packets with Setria® Glutathione and Sustamine® L-Alanyl-L-Glutamine 3Health News:Zaca Life Introduces Recovery Chewable Packets with Setria® Glutathione and Sustamine® L-Alanyl-L-Glutamine 4Health News:Mullin/Ashley Associates Takes Home Wins for Three Clients in the Service Industry Advertising Awards Annual Competition 2Health News:Mullin/Ashley Associates Takes Home Wins for Three Clients in the Service Industry Advertising Awards Annual Competition 3Health News:Bill Howe Plumbing, Heating & Air Launches Online Application to Prospective Employees 2Health News:Bill Howe Plumbing, Heating & Air Launches Online Application to Prospective Employees 3Health News:24/7 Care At Home Earns a 5-Star Rating from the Centers for Medicare and Medicaid (CMS) 2Health News:The Beryl Institute Opens Applications for 2015 Patient Experience Grant and Scholar Programs 2Health News:The Beryl Institute Opens Applications for 2015 Patient Experience Grant and Scholar Programs 3
    ... function problems in ill veterans , , TUESDAY, March 24 ... 1991 Gulf War appears to have triggered abnormal responses ... found. , They say the discovery could lead to ... Gulf War syndrome. , The study, from the ...
    ... eating fish, study finds , , TUESDAY, March 24 (HealthDay ... against advanced prostate cancer, researchers report. , Eating fish ... of developing advanced prostate cancer even if one is ... is needed to see if the association is real, ...
    ... against advanced prostate cancer, and this effect may be ... according to a report in Clinical Cancer Research ... Research. , "Previous research has shown protection against prostate ... to show protection against advanced prostate cancer and interaction ...
    ... YORK, March 24, 2009 Researchers may have found a more ... history of the deadly skin disease. In a new study, scientists ... to a nearly four-fold increase of melanoma in women under the ... 24, 2009, in the journal Clinical Cancer Research and ...
    ... WASHINGTONThe World Health Organization released staggering new data about the ... with HIV/AIDS today, in recognition of World TB Day. ... previously thought, the new WHO figures show. In 2007, there ... 15 percent of the total incident cases. That,s double the ...
    ... students who are problem drinkers using alcohol to cope ... to continue excessive drinking into adulthood, a recent study ... that adults who are still high-risk drinkers by age ... social and cognitive development that typically occurs during college, ...
    Cached Medicine News:Health News:Gulf War Syndrome May Stem From Chemical Exposure 2Health News:Omega-3 Fatty Acids Guard Against Advanced Prostate Cancer 2Health News:Omega-3 Fatty Acids Guard Against Advanced Prostate Cancer 3Health News:NYU study finds new risk factor for melanoma in younger women 2Health News:NYU study finds new risk factor for melanoma in younger women 3Health News:Alarming new data shows TB-HIV co-infection a bigger threat 2Health News:Study helps identify college drinkers who might continue excessive drinking as adults 2Health News:Study helps identify college drinkers who might continue excessive drinking as adults 3Health News:Study helps identify college drinkers who might continue excessive drinking as adults 4Health News:Study helps identify college drinkers who might continue excessive drinking as adults 5
    ... The Integra II SP MRI-Compatible Anesthesia System is ... using more than one type of anesthetic agent. ... vaporizers and due to its wider stance, has ... and ventilator bellows assembly is utilized in both ...
    The very bright medical maginifier lamp for examination and labratory....
    ... is the Market leader in soft tissue ... DePuy Mitek has developed the latest evolution ... shoulder repair. ORTHOCORD Suture is as strong ... market. Most importantly, ORTHOCORD Suture handles like ...
    ... The SuturTek 360Fascia Closure Deviceprotects ... suture needlesticks and the threat of ... suturing, while at the same time ... safely, quickly, and easily. The SuturTek ...
    Medicine Products: