Navigation Links
MAP Pharmaceuticals to Present Data From LEVADEX® Pharmacokinetics and Pharmacodynamics Safety Studies at the 63rd Annual Meeting of the American Academy of Neurology
Date:4/12/2011

MOUNTAIN VIEW, Calif., April 12, 2011 /PRNewswire/ -- MAP Pharmaceuticals, Inc. (Nasdaq: MAPP) today announced that the Company will present new data from two safety studies of LEVADEX® orally inhaled migraine drug.  The data will be presented at the 63rd Annual Meeting of the American Academy of Neurology (AAN) in Honolulu, Hawaii April 9-16, 2011.  LEVADEX is an investigational acute drug for migraine that has completed Phase 3 clinical development.

Findings to be presented at 2:00 p.m. HAST today in the poster titled "An Open-Label, 2-Period, Crossover Study Comparing the Pharmacokinetics and Tolerability of LEVADEX (MAP0004, Orally Inhaled DHE) and Intravenous DHE (DHE45) in Smoking and Non-Smoking Adult Volunteers," show that:

  • LEVADEX exposure was not higher in smokers, potentially due to reduced pulmonary absorption
  • LEVADEX was quickly absorbed into the bloodstream of both smokers and non-smokers, as evidenced by a median Tmax of 4.98 and 7.02 minutes respectively
  • The mean half-life for LEVADEX was similar for smokers (16.1 hours) and non-smokers (14.5 hours) and was similar to IV DHE administration (13.3 hours for smokers and 12.4 hours for non-smokers)
  • Tolerability of LEVADEX was similar in smokers and non-smokers

  • Findings in a separate safety study to be presented at 2:00 p.m.  HAST today in the poster titled "A Randomized, Double-Blind, Placebo Controlled, Three-Period Crossover Study Comparing the Acute Effects of LEVADEX (MAP0004, Orally Inhaled DHE) and Intravenous DHE on Pulmonary Arterial Systolic Pressure," show that:

  • Neither LEVADEX, IV DHE nor placebo produced clinically significant changes in pulmonary arterial systolic pressure (PASP) or other cardiac functions; however a statistically higher elevation of PASP was found following IV DHE treatment compared to the LEVADEX and placebo tr
    '/>"/>

  • SOURCE MAP Pharmaceuticals, Inc.
    Copyright©2010 PR Newswire.
    All rights reserved

    Page: 1 2 3 4

    Related medicine technology :

    1. Auxilium Pharmaceuticals, Inc. Receives Clearance to Resume Clinical Trials for XIAFLEX(TM)
    2. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
    3. Solvay Pharmaceuticals, Inc. and Wyeth Pharmaceuticals Announce Receipt of an FDA Action Letter for Bifeprunox, an Investigational Treatment for Schizophrenia
    4. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
    5. WallSt.net (www.wallst.net) Updates the Investment Community Through an All-New Interview With RegeneRx Biopharmaceuticals CEO
    6. Quark Pharmaceuticals, Inc. Presented Positive Preclinical Results of Systemic RNAi Compound for Acute Renal Failure (ARF)
    7. Peregrine Pharmaceuticals Doses First Patient in Cotara(R) Phase II Brain Cancer Trial In India
    8. Nabi Biopharmaceuticals Announces Second Quarter 2007 Financial Results
    9. Access Pharmaceuticals Provides Update on Clinical Development Plan of ProLindac
    10. Quark Pharmaceuticals Extends Research Agreement with State University of New York for Proprietary siRNA Compounds for Acute Hearing Loss
    11. Acura Pharmaceuticals, Inc. Secures Financing to Fund Pivotal Phase III Clinical Trial for Lead Aversion(R) Technology Product Candidate
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:7/10/2014)... July 10, 2014 Integrated Silicon Solution, Inc. ... memory and analog IC solutions, today announced that it ... 24, 2014, at 7:00 a.m. Pacific Time (10:00 a.m. ... the fiscal 2014 third quarter ended June 30, 2014. ... dial 1-888-556-4997 before 6:50 a.m. Pacific time on July ...
    (Date:7/10/2014)... 10, 2014  Valeant Pharmaceuticals International, Inc. (NYSE: ... has completed the sale to Galderma of all rights ... held by Valeant for $1.4 billion in cash, pursuant ... recently completed its acquisition of Galderma. ... products to a company that is firmly committed to ...
    (Date:7/10/2014)... -- CVS Caremark Corporation (NYSE: CVS ) today ... dividend of $0.275 (27.5 cents) per share on the corporation,s ... to holders of record on July 21, 2014. ... to helping people on their path to better health as ... States . Through the company,s more than 7,600 CVS/pharmacy ...
    Breaking Medicine Technology:
    (Date:7/11/2014)... Volunteers from Scientology Churches and Missions ... drug education lectures, forums and conferences, information stands, sports ... the world. , Drug abuse is an international epidemic. ... abuse of alcohol and illicit drugs costs more than ... productivity and healthcare. , In the face of ...
    (Date:7/11/2014)... (PRWEB) July 11, 2014 Datalogic brings ... in improving sanitation hospital wide. With their new ... spread of disease, like the devastating MRSA, which claimed ... Gryphon GD4400-HC 2D and the Gryphon GM4400-HC ... barcodes and can even read barcodes off of troublesome ...
    (Date:7/11/2014)... U.S. health officials have concluded that it,s highly unlikely ... a safety mishap last month. But, the U.S. ... a moratorium on the transfer of any dangerous germs ... report issued Friday, the CDC outlined several measures the ... doesn,t occur again. Last month, as many as 75 ...
    (Date:7/11/2014)... Global enterprises today are shifting towards ... management activities. Managed services offer these global enterprises a ... slowdown resulted into rising operational costs to companies. The ... to be the global market driver for expanding the ... managed services market is estimated to grow from $142.75 ...
    (Date:7/11/2014)... (July 10, 2014) Obese and overweight firefighters ... health care providers, according to new research from ... Houston (UTHealth). , National guidelines state that health ... importance of maintaining a healthy weight. Firefighters have ... the leading cause of line-of-duty deaths in firefighters. ...
    Breaking Medicine News(10 mins):Health News:Scientologists Taking Action against Drug Abuse 2Health News:Scientologists Taking Action against Drug Abuse 3Health News:Stop Spreading Disease with the New Disinfectant-Ready Bar Code Scanner 2Health News:Stop Spreading Disease with the New Disinfectant-Ready Bar Code Scanner 3Health News:CDC Issues Tough Report on Anthrax Scare 2Health News:North America Managed Services Market Worth $68.65 Billion by 2018 - New Report by MicroMarket Monitor 2Health News:North America Managed Services Market Worth $68.65 Billion by 2018 - New Report by MicroMarket Monitor 3Health News:North America Managed Services Market Worth $68.65 Billion by 2018 - New Report by MicroMarket Monitor 4
    ... and hyperactivity disorder (ADHD) are more than three times ... dementia than those without, according to research in the ... . Researchers from Argentina confirmed the link during ... 149 healthy controls, matched by age, sex and education. ...
    ... HealthDay Reporter , MONDAY, Jan. 17 (HealthDay News) -- ... actually measure up, according to new research. Dermatologists ... protection from the sun,s ultraviolet rays and found only ... which can penetrate glass. "The vast majority of ...
    ... and people in the southern United States who were newly ... years experienced greater HIV/AIDS-related morbidity compared to men and people ... The findings, published in the February 15 issue of ... to improve the health of these populations in order to ...
    ... HealthDay Reporter , MONDAY, Jan. 17 (HealthDay ... You tend to befriend others with similar or complementary ... University of California, San Diego found that gene clusters ... predisposition to befriend others in the same geographic area. ...
    ... other illnesses and patient embarrassment may prevent dermatologists, ... examinations, according to a report in the January ... of the JAMA/Archives journals. However, dermatologists are significantly ... conduct such screenings. Skin cancer is the ...
    ... HealthDay Reporter , MONDAY, Jan. 17 (HealthDay News) ... to the development of psychological disorders such as depression, researchers ... are more likely to become addicted to video games (which ... a lot of hours playing these games, have trouble fitting ...
    Cached Medicine News:Health News:Adult ADHD significantly increases risk of common form of dementia 2Health News:Adult ADHD significantly increases risk of common form of dementia 3Health News:Despite Claims, Many Daily Moisturizers Don't Shield Against Sun: Study 2Health News:Despite Claims, Many Daily Moisturizers Don't Shield Against Sun: Study 3Health News:Sex, race, and geography influence health outcomes following primary HIV infection 2Health News:Your Genes Help You Choose Your Friends, Study Says 2Health News:Your Genes Help You Choose Your Friends, Study Says 3Health News:Clinicians cite time, patient embarrassment as barriers to performing skin cancer exams 2Health News:Video Game 'Addiction' Tied to Depression, Anxiety in Kids 2Health News:Video Game 'Addiction' Tied to Depression, Anxiety in Kids 3
    Zebras H 2824-Z Healthcare Starter Kit includes everything you need to start printing wristbands today: the H 2824-Z direct thermal printer, a pre-installed Media Adapter Guide, and a roll of adult-s...
    ... Hugs® system software presents only ... a familiar Windows-based PC environment. Up ... connected at other locations throughout the ... network (LAN). Nurses, security personnel and ...
    ... is designed to protect a wandering resident ... lost or injured. Such residents typically have ... have suffered a head injury., At-risk residents ... wrist or ankle, and points of exit ...
    ... be programmed to send hospital-defined ... device needs servicing, preventive maintenance ... patient or staff member needs ... ID-tag includes the current location ...
    Medicine Products: