Navigation Links
MAP Pharmaceuticals Reports Positive Results From Comparative Pharmacokinetic Trial for its Pediatric Asthma Product Candidate
Date:3/24/2008

Lower systemic drug exposure observed compared to currently marketed

conventional nebulized budesonide

MOUNTAIN VIEW, Calif., March 24 /PRNewswire-FirstCall/ -- MAP Pharmaceuticals, Inc. (Nasdaq: MAPP) announced today that in a pharmacokinetic clinical trial Unit Dose Budesonide (UDB) demonstrated lower systemic drug exposure when compared to the currently marketed conventional nebulized budesonide. UDB is MAP Pharmaceuticals' proprietary nebulized formulation of budesonide, currently in Phase 3 clinical development, for the potential treatment of pediatric asthma. UDB is designed to be administered more quickly and to provide efficacy at lower doses than conventional nebulized budesonide, which is the current leading treatment for pediatric asthma.

The clinical trial was a randomized, open label, cross-over study evaluating the pharmacokinetic profile of two doses of UDB given twice daily in 32 adults with mild to moderate asthma. A 0.135 mg dose of UDB was compared as an alternative to a 0.25 mg dose of conventional nebulized budesonide given twice daily, and a 0.25 mg dose of UDB was compared as an alternative to a 0.5 mg dose of conventional nebulized budesonide given twice daily.

In this study UDB demonstrated faster times to maximum blood concentrations as compared to conventional nebulized budesonide, and had similar maximum blood concentrations. No serious adverse events were reported in the study and nebulization time for UDB in this adult population was shorter than for the currently marketed conventional nebulized budesonide product.

"We are pleased to confirm that the UDB doses we are evaluating as part of our Phase 3 clinical program resulted in lower systemic drug exposure c
'/>"/>

SOURCE MAP Pharmaceuticals
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Auxilium Pharmaceuticals, Inc. Receives Clearance to Resume Clinical Trials for XIAFLEX(TM)
2. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
3. Solvay Pharmaceuticals, Inc. and Wyeth Pharmaceuticals Announce Receipt of an FDA Action Letter for Bifeprunox, an Investigational Treatment for Schizophrenia
4. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
5. WallSt.net (www.wallst.net) Updates the Investment Community Through an All-New Interview With RegeneRx Biopharmaceuticals CEO
6. Quark Pharmaceuticals, Inc. Presented Positive Preclinical Results of Systemic RNAi Compound for Acute Renal Failure (ARF)
7. Peregrine Pharmaceuticals Doses First Patient in Cotara(R) Phase II Brain Cancer Trial In India
8. Nabi Biopharmaceuticals Announces Second Quarter 2007 Financial Results
9. Access Pharmaceuticals Provides Update on Clinical Development Plan of ProLindac
10. Quark Pharmaceuticals Extends Research Agreement with State University of New York for Proprietary siRNA Compounds for Acute Hearing Loss
11. Acura Pharmaceuticals, Inc. Secures Financing to Fund Pivotal Phase III Clinical Trial for Lead Aversion(R) Technology Product Candidate
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/21/2014)... Germany , Aug. 21, 2014  IBM (NYSE: ... Elektronen-Synchrotron ( DESY ), a leading national research center ... management and storage of massive volumes of x-ray data. ... based on IBM software defined technology can handle more ... performance and help scientists worldwide gain faster insights into ...
(Date:8/21/2014)... 2014  Seventy-one percent of Americans believe the abuse of ... public health and safety issue in the United ... today by Repass & Partners, a Cincinnati ... the severity of the prescription medication abuse problem and the ... serious health situation facing our country," Rex Repass , ...
(Date:8/21/2014)... 2014 BreedIT Corp., (OTCQB: ... exclusive worldwide license holder and distributor of highly ... researchers, today is pleased to announce the formation ... Ltd, a leading Israeli medical Cannabis breeder. ... new breeds of medical Cannabis to meet the ...
Breaking Medicine Technology:DESY and IBM Develop Big Data Architecture for Science 2DESY and IBM Develop Big Data Architecture for Science 3Consumers Desperate For Measures To Curb Prescription Drug Abuse 2Consumers Desperate For Measures To Curb Prescription Drug Abuse 3BreedIT Ltd. and Seach Ltd. Form KanaboSeed to Develop New Medical Cannabis Varieties 2BreedIT Ltd. and Seach Ltd. Form KanaboSeed to Develop New Medical Cannabis Varieties 3BreedIT Ltd. and Seach Ltd. Form KanaboSeed to Develop New Medical Cannabis Varieties 4
... BUDAPEST, Hungary , January ... Globally Licenses ChemAxon,s Platform For Markush Structure,Searching And Enumeration , ... cheminformatics software for the life,sciences industry has entered into agreement ... for global,development and deployment within Pfizer,s global R&D facilities. , ...
... ... to Improve Walking for People With All Types of Multiple Sclerosis ... The U.S. Food and Drug Administration has approved the marketing of ... its ability to improve walking speed in people with any type ...
Cached Medicine Technology:Ampyra is First Symptom Management Drug Developed Specifically to Treat MS, the First Oral MS Therapy Approved for MS, and the First New FDA Approved Therapy to Come Through the MS Pipeline Since 2004 2Ampyra is First Symptom Management Drug Developed Specifically to Treat MS, the First Oral MS Therapy Approved for MS, and the First New FDA Approved Therapy to Come Through the MS Pipeline Since 2004 3Ampyra is First Symptom Management Drug Developed Specifically to Treat MS, the First Oral MS Therapy Approved for MS, and the First New FDA Approved Therapy to Come Through the MS Pipeline Since 2004 4Ampyra is First Symptom Management Drug Developed Specifically to Treat MS, the First Oral MS Therapy Approved for MS, and the First New FDA Approved Therapy to Come Through the MS Pipeline Since 2004 5Ampyra is First Symptom Management Drug Developed Specifically to Treat MS, the First Oral MS Therapy Approved for MS, and the First New FDA Approved Therapy to Come Through the MS Pipeline Since 2004 6
(Date:8/22/2014)... The world’s largest, most active billionaire/ millionaire ... millionth member, and it has since greatly exceeded the ... dating website for the rich looking for attractive and ... caters like-minded people who are admirers, millionaires and billionaires. ... , this is the place where rich people can ...
(Date:8/22/2014)... 2014 First Choice Emergency Room ... facility is located at 8927 Highway 6, Missouri City, Texas ... is pleased to be a part of the Missouri City ... medical care to our neighbors here,” said Dr. Kenneth Jones, ... , At yesterday’s ribbon cutting with the Fort ...
(Date:8/22/2014)... Toledo, OH (PRWEB) August 22, 2014 Teen ... people in Toledo, OH. The rising numbers of young adults ... have been staggering. To help make a difference in the ... provide a valuable resource for teens seeking to overcome their ... their teens find the best youth rehab center to focus ...
(Date:8/22/2014)... CA (PRWEB) August 22, 2014 Dr Murray ... for this snoring cure. , In the October 2014 issue ... of Dr Grossan about his method of treating snoring, and ... quotes Dr Grossan: "Nearly half of all adults snore occasionally, ... This is because air passages in the back of ...
(Date:8/21/2014)... Os-Monitor.com, an outstanding online supplier of ... monitoring software collection ( http://www.os-monitor.com ). In addition ... all these high end items are offered with ... of improving productivity, the employers pay more attention ... employee and network monitoring software products are becoming ...
Breaking Medicine News(10 mins):Health News:Rich Men & Women Dating Site Billionairefish.com Exceeds Two Million Members 2Health News:Rich Men & Women Dating Site Billionairefish.com Exceeds Two Million Members 3Health News:First Choice Emergency Room Opens New Facility in Missouri City, Texas 2Health News:New Helpline Provides Hope for Troubled Teens in Toledo 2Health News:Dr Murray Grossan Explains how and why Singing Exercises Stop Snoring 2Health News:Dr Murray Grossan Explains how and why Singing Exercises Stop Snoring 3Health News:New Employee Monitoring Software Collection Unveiled By Os-Monitor.com 2
... , , WASHINGTON, Dec. 21 ... the manager,s amendment which includes abortion language that would force ... that will cover any or all abortions while doing nothing ... the legislation has a myriad of other problems including increasing ...
... More than 40 groups have joined together to oppose ... Vigil" starting at 9 pm tonight and wrapping after the ... millions on the left, right, seniors, tea parties, doctors, libertarians, ... for laying a $200 billion windfall in mandatory premiums at ...
... ... named two QHR management clients to its “Top 100 Hospitals: Best ... a QHR management client since 1982, and Monroe County Hospital (Monroeville, ... company, which specializes in providing hospitals and other healthcare-related businesses with ...
... Political ... for biggest lies also include claims by President Barack Obama and Vice President Joe ... Washington ... of the St. Petersburg Times, has named Sarah Palin,s claim about "death panels" the ...
... , WASHINGTON, Dec. 20 Following is the ... http://www.newscom.com/cgi-bin/prnh/20090226/CENSUSLOGO ) , SUNDAY, DECEMBER 20: FIRST ORGAN ... The first successful organ transplant in the U.S. was performed this ... He transplanted a kidney from one identical twin to another, who ...
... care focuses on costs, a new study from North Carolina ... think of health care spending as an investment that can ... of health care costs and financing may be unduly pessimistic. ... in future capital, contributing to a productive workforce, rather than ...
Cached Medicine News:Health News:FRC Asks - 'Is There No Democratic Senator Who Cares About Life?' 2Health News:Left/Right Healthcare 'Virtual Vigil' Tonight at 9 PM Until Senate Votes; Broad Coalition Says Punishes Some States, Windfall for Insurance Companies 2Health News:QHR Hospital Clients Fort Madison Community Hospital, Monroe County Hospital Named to “Best in Value” Top 100 List 2Health News:PolitiFact Names 'Death Panels' Claim the Lie of the Year 2Health News:U.S. Census Bureau Daily Feature for Dec. 20 2Health News:Study shows health care spending spurs economic growth 2
... Slab Gel Dryer accommodates large sequencing gels or multiple ... coated platen for long lasting durability and corrosion resistance., ... , Quick Drying Rate - large sequence ... , Digital display of temperature and time ...
... The Slimline SGD5040 Slab Gel Dryer incorporates sturdy metal ... saving design. The large surface area makes it perfect ... ones., Slim Profile 40cm x 50cm (W ... Heat Ramping Rates allows you to optimize ...
... midi gel dryer can dry 6 pieces of 10 ... area is 21 x 31 cm for laboratories to ... of silicon rubber with mask. Microprocessor controller controls temperature ... and the vacuum removes the moisture from below to ...
... dry gels rapidly, evenly and safely, the Hoefer ... and vacuum are applied beneath the gel through ... and agarose gels up to 33 x 44 ... heavy aluminum platen provides even heat distribution and ...
Medicine Products: