Navigation Links
MAP Pharmaceuticals Reports Positive Pharmacological Response Data for Migraine Product Candidate at the American Headache Society Annual Meeting
Date:6/28/2008

MOUNTAIN VIEW, Calif., June 28 /PRNewswire-FirstCall/ -- MAP Pharmaceuticals, Inc. (Nasdaq: MAPP) today presented data from an in-vitro study evaluating receptor pharmacology of MAP0004, orally inhaled dihydroergotamine (DHE) for the potential treatment of migraine, compared to intravenous (IV) DHE. The study results were among six posters relating to the MAP0004 program that the Company presented at the American Headache Society 50th Annual Scientific Meeting in Boston, MA.

In this receptor pharmacology study, MAP0004 stimulated receptors that relieve migraine at levels comparable to IV DHE, but did not activate receptors associated with side effects frequently seen with IV DHE. In addition, MAP0004 did not affect receptors that have a role in regulating pulmonary function.

"The selective binding of MAP0004 at receptors associated with migraine rather than those associated with side effects offers a mechanistic hypothesis for the favorable safety and efficacy profile of MAP0004 compared to IV DHE that we have observed in our initial clinical studies," said Thomas A. Armer, Ph.D., Chief Scientific Officer of MAP Pharmaceuticals. "The absence of negative effects of MAP0004 on pulmonary function in asthmatic subjects observed in a Phase 2 study is also important because migraine and asthma are frequently co-morbid conditions."

MAP0004 is designed to be self-administered by patients at home via MAP Pharmaceuticals' proprietary Tempo(R) inhaler. In Phase 2 studies with migraneurs and with asthmatics, treatment with MAP0004 was well-tolerated, with no serious adverse events reported. Drug-induced nausea was very low and migraine-associated nausea also decreased with treatment.

The Company presented a poster summariz
'/>"/>

SOURCE MAP Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Phase III Data Show Vanda Pharmaceuticals Tasimelteon (VEC-162) Significantly Improves Sleep in Patients with Chronic Insomnia
2. Morria Biopharmaceuticals Plc Announces the Initiation of a Phase II Clinical Multi-dose Study of MRX-4 in Allergic Rhinitis
3. Alexza Pharmaceuticals to Present AZ-104 Phase 2a Clinical Data at the American Headache Society Annual Scientific Meeting
4. Trubion Pharmaceuticals Announces Extension of Research Period Under Its Wyeth Collaboration
5. Peregrine Pharmaceuticals Awarded Two New U.S. Patents Broadening Its Targeted Anti-Phospholipid Patent Portfolio
6. Trubion Pharmaceuticals Announces Presentation of Positive TRU-015 and SBI-087 Data at the 2008 Annual European Congress of Rheumatology Meeting
7. Quatrx Pharmaceuticals Presents Results From Ophena(TM) (Ospemifene Tablets) Phase 3 Study Related to Treatment of Symptoms of Vulvovaginal Atrophy
8. Sunesis Pharmaceuticals Presents Data from Clinical Trials of Voreloxin (formerly SNS-595) in Patients with Acute Myeloid Leukemia at the 13th Congress of the European Hematology Association
9. European Enrollment Begins in Pivotal Phase 3 Trial of Novel Combination Medicine Developed by Cogentus Pharmaceuticals
10. Vion Pharmaceuticals Announces Presentation of Data of Cloretazine(R) (VNP40101M) in Elderly Patients with High-Risk Myelodysplastic Syndromes at the EHA Annual Meeting
11. Arena Pharmaceuticals Presented Positive Phase 2a Clinical Trial Results of APD125 for the Treatment of Insomnia at 22nd Annual Meeting of the Associated Professional Sleep Societies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/14/2014)... , Jan. 14, 2014  Luminex Corporation (Nasdaq: LMNX ... the fourth quarter of 2013 on Monday, February 3, 2014. ... after the close of trading. (Logo: ... to discuss the operating highlights and financial results for the ...
(Date:1/14/2014)... Jan. 14, 2014 /PRNewswire-iReach/ -- Acumed,s new SLIC Screw ... with accompanying instrumentation to place and insert the screw ... soft tissue (e.g. ligament) repair or reconstruction as it ... (Photo: http://photos.prnewswire.com/prnh/20140114/MN45636 ) ...
(Date:1/14/2014)... Jan. 14, 2014   Oligomerix, Inc. , a privately held ... Alzheimer,s disease (AD) and related neurodegenerative disorders, announced today ... Valhalla, NY as of January 15, 2014 ... New York Medical College. Oligomerix, which is ...
Breaking Medicine Technology:Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 2Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 3Acumed introduces the Scapho-Lunate Inter Carpal (SLIC) Screw System 2Acumed introduces the Scapho-Lunate Inter Carpal (SLIC) Screw System 3Oligomerix Relocates Corporate Headquarters and Secures Additional Laboratory Space from New York Medical College 2
... Misonix, Inc. (NASDAQ: MSON ), ... markets innovative therapeutic ultrasonic products worldwide for wound ... surgical and medical applications, today reported financial results ... 2011.  Michael A. McManus Jr., President and Chief ...
... Mich., Nov. 9, 2011 Everist Genomics, ... and commercializing innovative diagnostics and prognostics, today ... system.  CardioDefender is the first FDA-approved and ... physicians and patients with hospital-quality heart rhythm ...
Cached Medicine Technology:Misonix Reports a 14.8% Increase in Revenue for the First Quarter Fiscal 2012 Financial Results 2Misonix Reports a 14.8% Increase in Revenue for the First Quarter Fiscal 2012 Financial Results 3Misonix Reports a 14.8% Increase in Revenue for the First Quarter Fiscal 2012 Financial Results 4Misonix Reports a 14.8% Increase in Revenue for the First Quarter Fiscal 2012 Financial Results 5Misonix Reports a 14.8% Increase in Revenue for the First Quarter Fiscal 2012 Financial Results 6Everist Genomics to Launch CardioDefender: World's Only Mobile ECG System that Delivers Real-time, Beat-by-beat, Quantitative Heart Monitoring Data to Physicians 2Everist Genomics to Launch CardioDefender: World's Only Mobile ECG System that Delivers Real-time, Beat-by-beat, Quantitative Heart Monitoring Data to Physicians 3Everist Genomics to Launch CardioDefender: World's Only Mobile ECG System that Delivers Real-time, Beat-by-beat, Quantitative Heart Monitoring Data to Physicians 4Everist Genomics to Launch CardioDefender: World's Only Mobile ECG System that Delivers Real-time, Beat-by-beat, Quantitative Heart Monitoring Data to Physicians 5
(Date:4/18/2014)... Johns Hopkins University School of Medicine researchers have been ... for diabetes, Novo Nordisk announced this month. Of the ... and Obesity Biologics Science Forum Program, only four projects ... Hopkins researchers. They are Jonathan Powell, M.D., Ph.D.; G. ... , Jonathan Powell, a professor of oncology, will use ...
(Date:4/18/2014)... 2014) ― A new study in the American ... health-related Google searches reveals a recurring pattern that could ... , Investigators from San Diego State University, the Santa ... analyzed "healthy" Google searches (searches that included the term ... in the U.S. from 2005 to 2012. They found ...
(Date:4/17/2014)... of chronic inflammation in non-cancerous prostate tissue may have ... than those with no inflammation, according to results of ... Hopkins Kimmel Cancer Center. , The link between persistent ... so-called high-grade prostate cancer those with a Gleason ... of the most aggressive and rapidly growing prostate cancers. ...
(Date:4/17/2014)... According to a study published today in PLOS ... world where malaria is common can mount an immune ... them to avoid repeated bouts of high fever and ... in their bloodstream. The findings may help researchers develop ... by the malaria parasite. , Each year, approximately 200 ...
(Date:4/17/2014)... a review published in the April issue of ... Feinstein Institute for Medical Research, says it,s time to ... approach to treating sepsis, which kills millions worldwide ... occurs when molecules released into the bloodstream to fight ... Inflammation is necessary for maintaining good health without ...
Breaking Medicine News(10 mins):Health News:New research shows people are thinking about their health early in the week 2Health News:Chronic inflammation linked to 'high-grade' prostate cancer 2Health News:Chronic inflammation linked to 'high-grade' prostate cancer 3Health News:Study sheds light on how the immune system protects children from malaria 2Health News:Feinstein Institute researcher publishes new perspective on sepsis 2
... value in health care: What should we pay for and ... health care should be balanced against various realities--including the effectiveness ... Especially in a depressed economy, questions about value in health ... reform debates. , In a commentary published in Health ...
... 26 Krause, Kalfayan, Benink & Slavens, LLP filed ... Court on behalf of a putative class of California ... years, Scripps Health billed for medical services after their ... emergency medical bills. The lawsuit alleges that ...
... COLUMBUS, Ga., Jan. 26 Aflac Incorporated,announced today that ... will webcast a conference call scheduled for 9:00 a.m. ... in addition to the previously,announced fourth quarter webcast meeting ... During the morning teleconference on February 3, ...
... For Needed Enforcement of Canon 915; Withholding Eucharist From ... American Life League executive director Shaun Kenney issued the ... Pelosi,s interview with ABC News on Sunday. Rep. Pelosi ... in the economic stimulus package would "reduce costs to ...
... on interoperability specifications from the Healthcare Information Technology Standards Panel ... ... Chicago (Vocus) January 26, 2009 -- With the economic ... domestic priorities identified in Tuesday,s inaugural address, with President Obama ...
... United American Healthcare,Corporation (Nasdaq: UAHC ), a ... financial results for the second fiscal,quarter ended December 31, ... The Company will host a conference call at 4:30 ... , Participation in the call,s ...
Cached Medicine News:Health News:Can payment and other innovations improve the quality and value of health care? 2Health News:KRAUSE, KALFAYAN, BENINK & SLAVENS, LLP, Announces Filing a Class Action Lawsuit Against Scripps Health, et al. 2Health News:Aflac Announces Additional Teleconference Webcast 2Health News:American Life League Statement on Pelosi's State-Enforced War on Preborn Babies 2Health News:Achieving Interconnected Healthcare through HITSP Real-Life Scenarios 2Health News:Achieving Interconnected Healthcare through HITSP Real-Life Scenarios 3Health News:Achieving Interconnected Healthcare through HITSP Real-Life Scenarios 4Health News:Achieving Interconnected Healthcare through HITSP Real-Life Scenarios 5Health News:Achieving Interconnected Healthcare through HITSP Real-Life Scenarios 6Health News:United American Healthcare Corporation to Host Fiscal 2009 Second Quarter Results Conference Call February 5th 2
... with 24-well x 0.2ml sub-ambient block and ... thermistor) Heating rates: up to 3C/second; Accurate ... Excellent uniformity: better than 0.5C within 15 ... programming: directory program storage of up to ...
... maximizes what a thermal cycler can do ... formats, an easy graphic interface, and best ... PCR. The iCycler thermal cycler will raise ... can do for you.,, iCycler Thermal Cycler ...
Contains: Card, cabling and instructions to remotely access a RoboCycler® instrument from a PC or Macintosh® computer...
... RoboCycler Gradient 40 or 96 temperature cyclers, the ... linear temperature range of up to 14 or ... with a temperature difference of up to 2C ... you can test up to 12 different annealing ...
Medicine Products: