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M. D. Anderson to Initiate Clinical Validation Study on Rosetta Genomics' MicroRNA-based Diagnostic Assay Identifying the Origin of Cancer Metastases
Date:8/11/2008

The Study Will Correlate the Results of Rosetta Genomics' MicroRNA-Based CUP Assay With Diagnostic Work Conducted at M.D. Anderson Cancer Center Data on the Company's MicroRNA-Based CUP Assay and its High Sensitivity and Accuracy was Recently Published in the April Issue of Nature Biotechnology

REHOVOT, Israel and JERSEY CITY, New Jersey, August 11 /PRNewswire-FirstCall/ -- Rosetta Genomics, Ltd. (NASDQ: ROSG), a leader in the development of microRNA-based diagnostic and therapeutic products, announced today the initiation of a clinical validation study with The University of Texas M. D. Anderson Cancer Center (MDACC). The study will focus on Rosetta Genomics' microRNA-based test that identifies the primary site of cancer of unknown primary (CUP). The study will include one hundred patients who are diagnosed with CUP at MDACC, and who meet the eligibility criteria. Rosetta Genomics expects this test to be submitted for regulatory approval in the second half of 2008.

"The initiation of this validation study is an integral part of the commercialization roadmap for our diagnostic tests, as we advance them towards use in a clinical setting," said Amir Avniel, President and CEO of Rosetta Genomics. "We believe the initiation of this study for our CUP assay with a leading cancer research center such as M. D. Anderson attests to the critical unmet need this test addresses." CUP is a heterogeneous group of cancers that constitutes 3-5% of all cancers with a poor median survival of 6-10 months(1). Each year, approximately 70,000 patients in the United States are diagnosed with CUP. A patient is typically diagnosed with CUP only after undergoing a wide range of tests, including various imaging tests such as x-ray, CT, MRI, and PET, which often fail to identify the origin of the cancer.

Presently, the choice of treatment for metastatic cancer is largely dependent on the nature of the primary tumor. Patients with CUP pose a therapeutic dilemma and t
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SOURCE Rosetta Genomics Ltd
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