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Lung Cancer Study Reveals Similar Outcomes for African-American and Caucasian Patients Treated With Alimta®
Date:9/20/2011

.  The unadjusted DCR, or raw data, was 45.8 percent (27 of 59 patients) for the African American study arm and 43.4 percent (116 of 267 patients) for the Caucasian arm.  The odds ratio, a measure of whether a response is more likely in one population than another, indicated the proportions were similar.  This was true on the raw data, as well as after adjustment for relevant factors such as age, gender, smoking status and income.

Median survival for African American patients in the study was 6.9 months (95% CI: 4.5, 8.9) compared with 6.7 months (95% CI: 5.7, 7.9) for Caucasian patients.  In addition, African American patients achieved 3.0 months (95% CI: 2.3, 4.7) of median progression-free survival compared with 2.7 months (95% CI: 2.4, 3.4) for Caucasian patients.  The results indicate that the DCR was non-inferior for African American compared to Caucasian NSCLC patients receiving ALIMTA in this study.

"Traditionally, the vast majority of lung cancer studies have involved Caucasians, so physicians had no way of knowing whether the same results would hold true for other ethnic groups, such as African Americans," said Coleman Obasaju, M.D., Ph.D., senior medical director at Lilly Oncology.  "These kinds of studies help us begin to close this gap and improve health outcomes for all ethnicities."

As part of Lilly's goal to improve health outcomes for individual patients, the company is increasing enrollment of diverse populations in clinical trials and making it easier for patients in minority communities to participate.  Lilly's clinical trial strategy includes forming partnerships with other organizations committed to the same goal, and making efforts to educate and encourage physicians and patients to understand the importance of diverse representation in clinical trials.

About Non-Small Cell Lung Cancer (NSCLC)

Globally, lung cancer is the most common form of cancer and the biggest kil
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SOURCE Eli Lilly and Company
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