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Lung Cancer Study Reveals Similar Outcomes for African-American and Caucasian Patients Treated With Alimta®
Date:9/20/2011

INDIANAPOLIS, Sept. 20, 2011 /PRNewswire/ -- Lung cancer, the leading cause of cancer death in the U.S., takes a particularly heavy toll on African Americans.  Despite their lower smoking rates, African Americans are more likely than Caucasians to develop and die from lung cancer.(1)(2)  

Today, Eli Lilly and Company (NYSE: LLY) announced results of a prospective observational study that evaluated whether ethnicity affected outcome in stage IIIB/IV non-small cell lung cancer (NSCLC) patients treated with ALIMTA® (pemetrexed for injection) in the second-line setting.  The study found that the disease control rate (one of the measures for evaluating the effectiveness of NSCLC therapies) among African Americans was non-inferior to that of Caucasians.

Results of the study were announced today at the American Association for Cancer Research (AACR) annual "Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved" meeting in Washington, D.C.

"Few prospective lung cancer studies have looked at the impact of race and ethnicity on clinical outcomes," said Lee Schwartzberg, M.D., FACP, president and chief medical officer at ACORN Research, LLC and one of the study's investigators.  "But as cancer researchers, determining how ethnicity influences treatment should be just as important as discovering the role of a gene mutation in predicting therapeutic success."

Disease Control Rate, or DCR, is defined as the percentage of patients with a partial or complete response to a drug, plus the percentage of patients whose disease has stabilized. DCR could be a more powerful predictor of how a drug will affect survival than the traditional measure of tumor response to therapy (the sum of complete response plus partial response).

Information on DCR was available for 267 Caucasians and 59 African Americans
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SOURCE Eli Lilly and Company
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