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Lung Cancer Alliance Again Salutes NCI for its Now Published Work on Lung Cancer Screening Study Which Proved a 20 Percent Mortality Benefit for Those at Risk for Lung Cancer Using CT Scans
Date:6/29/2011

WASHINGTON, June 29, 2011 /PRNewswire-USNewswire/ -- Lung Cancer Alliance (LCA) congratulated the National Cancer Institute (NCI) on the publishing of additional and extensive data from its National Lung Screening Trial (NLST) in the New England Journal of Medicine (NEJM).  

The NLST, one of the largest and most expensive clinical trials ever held, was designed to evaluate CT screening compared to chest x-ray as a way to reduce lung cancer deaths, which currently account for nearly a third of all cancer fatalities.

The eight year trial was stopped last November as soon as it became evident that giving CT scans to current and former smokers before they had symptoms could reduce the number of people who died of lung cancer by over 20% as compared to chest x-rays. Screening with chest x-rays, the comparison arm in the NLST and the subject of several previous trials, again failed to show a benefit.

The additional data released by NCI today indicated that few harms resulted from CT screening and the rate of complications from the diagnostic work up was less than 2%.

"Today's publication gives researchers, policy makers, and the public full access to primary findings from the NLST to guide the use of low-dose helical CT scanning by current and former smokers," said Harold Varmus, MD, NCI Director.  

Laurie Fenton Ambrose, LCA President & CEO, thanked NCI for its investment in the trial which, because of the overwhelming number of lung cancer deaths that occur each year, has the potential to bring about the biggest single reduction ever in overall cancer mortality.

Fenton Ambrose said, "With the additional data NCI released today, and with more still being analyzed, along with the data continuing to be generated in on-going lung cancer CT screening research around the world, we can accelerate efforts to insure that this benefit is optimized in a safe, efficient and equitable way to those at risk for lung canc
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SOURCE Lung Cancer Alliance
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