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Lotrel, a Single-Pill Combination for Treating High Blood Pressure, Reduced Cardiovascular Events by 20% in High-Risk Patients
Date:3/31/2008

ponsored by the National Heart, Lung and Blood Institute recommend initial combination therapy of two medications that work differently for patients who have a systolic blood pressure of 20 mmHg and a diastolic blood pressure of 10 mmHg over target goal. Systolic blood pressure is the pressure of blood flow as the heart beats and pushes blood throughout the body. Diastolic blood pressure is between heart beats, as your heart rests and refills with blood.

Approximately 73 million adults (nearly one in three) in the US have high blood pressure. It has been estimated that most adults with high blood pressure also have additional health problems that increase their risk for cardiovascular events.

Novartis: strength in cardiovascular and metabolic diseases

Novartis is focused on improving the lives of the hundreds of millions of people with diseases of the cardiovascular and metabolic systems. As a global leader and innovator in cardiovascular and metabolic health, Novartis provides novel therapies and support programs to treat high blood pressure and major public health issues. The strength of Novartis lies in its broad range of renin-angiotensin system (RAS) based therapies for the treatment of high blood pressure, which include the most prescribed angiotensin-receptor-blocker, the first approved oral direct renin inhibitor and a single agent combining two of the most prescribed antihypertensive medicines. Novartis has an extensive clinical research program in hypertension involving more than 100,000 patients. Novartis is dedicated to helping physicians and patients address cardiovascular and metabolic health through effective medicines and an ongoing commitment to education, support and research.

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The foregoing release contains forward-looking statements that can be identified by terminology such as "will", "suggest", "committed", or similar expressions, or by express or implied discussions regarding potential new indicatio
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SOURCE Novartis Pharmaceuticals Corporation
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