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Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía
Date:9/2/2014

controlados. Aunque es esencial para evaluar la eficacia y seguridad de los nuevos tratamientos, estos ensayos no son representativos de las prácticas clínicas del día a día, y por ello, persiste la incertidumbre en torno a la carga de la vida real y tratamiento de la enfermedad. GARFIELD-AF busca proporcionar visiones sobre el impacto de la terapia anticoagulante sobre complicaciones tromboembólicas y hemorrágicas vistas en esta población de pacientes. Proporcionará un conocimiento mejor de las oportunidades potenciales para mejorar el tratamiento y los resultados clínicos entre un representante y un grupo diverso de pacientes y por medio de las diferentes poblaciones. Esto deberá ayudar a los médicos y sistemas de salud a adoptar de forma apropiada la innovación de cara a asegurar los mejores resultados para los pacientes y poblaciones.

El registro comenzó en diciembre de 2009. Cuatro características de diseño claves del protocolo GARFIELD-AF aseguran una descripción completa y representativa de la AF:

  • Cinco cohortes secuenciales de los pacientes prospectivos y de nueva diagnosis, facilitando las comparaciones de los periodos de tiempo discretos y la descripción de la evolución de los tratamientos y resultados.
  • Los sitios de los investigadores se seleccionan de modo aleatorio con una asignación cuidadosa de los cuidados de AF estableciendo distribuciones, asegurando que la población de pacientes reclutados es representativa.
  • El reclutamiento de los pacientes consecutivos seleccionables se lleva a cabo sin tener en cuenta la terapia para eliminar la inclinación hacia la selección potencial.
  • Los datos de seguimiento son capturados para un mínimo de entre 2 y 8 años tras la diagnosis, para crear una base de datos completa de las decisiones de tratamiento y los r
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SOURCE GARFIELD-AF
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