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Los datos sobre fibrilación atrial muestran agentes antitrombóticos no usados óptimamente para prevenir la apoplejía
Date:9/2/2014

entó del 60,6 al 67,5 % en el mismo período, ya que pocos pacientes recibieron un VKA (57,5 a 41,1 %).

Los 12.448 pacientes prospectivos con al menos un año de datos de seguimiento tras el diagnóstico de AF en el momento del análisis se incluyeron en tres pósters presentados en el ESC Congress 2014.

Sólo el 25 % de los pacientes tratados con VKAs logran un adecuado control anticoagulación[3]  

  • Las directrices del ESC sugieren que los pacientes se pueden considerar bien tratados en la terapia VKA si invierten al menos el 70% de su tiempo en el abanico terapéutico, por ejemplo, con una media internacional normalizada (INR) de 2,0-3,0[4].
  • El requisito para los pacientes con VKA de someterse a un control de rutina y ajuste de dosis, además de la dificultad para mantener el efecto anticoagulante óptimo, son de una consideración importante cuando se elige entre terapias anticoagulantes. Las NOACs se dan en dosis fijas y ejercen un efecto anticoagulante predecible sin necesidad de control.
  • De los 5.107 pacientes de GARFIELD-AF tratados con VKAs y con registros INR disponibles, solo el 25% (n=1.301) cumplen con el estándar del 70% para el control VKA (con el control INR evaluado como frecuencia en la gama (FIR)).
  • Los pacientes cuyo control VKA fue sub-óptimo fueron mucho más propensos a padecer apoplejía, un evento hemorrágico importante, y fallecimiento.

2 de cada 5 pacientes de bajo riesgo reciben anticoagulación frente a las recomendaciones de las directrices[5]  

  • Los pacientes que padecen AF y con una puntuación de riesgo CHA2DS2-VASc[6] de 0 se consideran por las directrices ESC co
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SOURCE GARFIELD-AF
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