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Long-term Use of Antiepileptic Drug Vimpat® (Lacosamide) C-V Reduced Seizure Frequency and Severity and Improved Health-related Quality of Life Measures
Date:12/5/2011

g/day.  However, the maximum FDA-approved dose for Vimpat® is 400 mg/day.

Abstract 2.244: Effect of Long-Term Lacosamide on Patient-Reported Health-Related Quality of Life and Seizure Severity by Seizure Subtype

This analysis of pooled data from open-label extensions of three Phase II/III trials demonstrated that long-term lacosamide therapy was associated with improvements in HRQoL and substantial reductions in seizure severity among adults with complex partial seizures (CPS) and secondary generalized partial seizures (SGPS) who responded to treatment.  Improvements in HRQoL and reduction in seizure severity were greater in patients who achieved a 50 percent reduction in seizure frequency compared to individuals who did not respond to treatment. 

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