Navigation Links
Long-Term Safety and Efficacy Data on Promacta(TM) (Eltrombopag) Presented at American Society of Hematology Annual Meeting
Date:12/10/2007

Preliminary results demonstrate patients with chronic idiopathic thrombocytopenic purpura increased and maintained platelet counts at greater than or equal to 50,000/microliters with extended treatment

ATLANTA, Dec. 10 /PRNewswire-USNewswire/ -- GlaxoSmithKline today announced data on the long-term safety and efficacy of its investigational drug PROMACTA(TM) (eltrombopag) for the treatment of chronic idiopathic thrombocytopenic purpura (ITP).(1) These preliminary results from the EXTEND (Eltrombopag eXTENded Dosing) study showed that of the patients with a baseline platelet count of less than 30,000/microliters, 73% achieved a platelet count of greater than or equal to 50,000/microliters. The average treatment period for all patients, from this ongoing treatment study, has lasted almost 22 weeks (five months) so far. These results suggest that PROMACTA sustains increased platelet counts during long-term treatment.(1) This research was presented at the 49th Annual Meeting of the American Society of Hematology, December 8-11 2007 in Atlanta, GA.

PROMACTA is an investigational compound that has not received regulatory approval in any market for any indication at this time.

PROMACTA was generally well tolerated in this study. Of the 94 patients who received at least one dose of PROMACTA, 83% reported at least one adverse event (AE), 32% reported a drug-related AE and 13% reported a serious AE (SAE). Most AEs were mild in severity with the most common being headache (20%).(1)

Chronic ITP is a disorder characterized by low levels of platelets in the blood, with patients suffering from excessive bruising and bleeding and in some cases having serious hemorrhages that can be fatal.(2,3,4) An estimated 200,000 individuals are diagnosed with ITP in the U.S.(5) and a similar number in Europe. PROMACTA is an investigational oral, non-peptide, platelet growth factor that induces the proliferation and differentiation of cells in the bone
'/>"/>

SOURCE GlaxoSmithKline
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. New Study Proves That Minimally Invasive Aneurysm Treatment Yields Successful Long-Term Results
2. Cypher(R) Sirolimus-Eluting Coronary Stent Demonstrates Sustained Clinical Benefits Compared to Bare Metal Stents in Five-Year Randomized Clinical Trial With No Differences in Long-Term Safety
3. Sexual Function Affected by Stem Cell Transplant According to Long-Term Study
4. Neupro(R) (Rotigotine Transdermal System) Effective in Controlling Early Morning Motor Impairment and Generally Well-Tolerated for Long-Term Use in Patients with Parkinsons Disease
5. Horizon Therapeutics Initiates Long-Term Phase 3 Safety Study for Lead Product Candidate HZT-501
6. New Analyses of Long-Term LIALDA(TM) (mesalamine) Data Presented at ACG
7. Long-Term 12-Month Safety Data Presented on ADHD Patch DAYTRANA(TM) (methylphenidate transdermal system)
8. Long-Term Data from a Landmark Phase III Trial Show Survival Benefit at Three- and Four-Years in Patients with Glioblastoma multiforme
9. Nabi Biopharmaceuticals Announces Successful Completion of NicVAX(R) Phase 2b Trial; Drug Shows Statistically Significant Rates of Smoking Cessation and Continuous Long-Term Smoking Abstinence at 12 Months
10. Human Genome Sciences Reports Positive Data from Long-Term Treatment with LymphoStat-B(R) in Patients with Active Systemic Lupus Erythematosus
11. Five-Year Data Demonstrate Long-Term Efficacy and Safety with ORENCIA(R) (abatacept) in Adults with Rheumatoid Arthritis Who had an Inadequate Response to Methotrexate
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... Aug. 29, 2014 Medina Medical announced today ... member of the Board of Directors on August 18, ... development and commercialization experience, including over a decade of ... served as a Partner of the medical device incubator ... of two Foundry start-ups. Mr. Engelson previously served as ...
(Date:8/29/2014)... Aug. 29, 2014 Thoratec Corporation (NASDAQ: ... circulatory support therapies to save, support and restore failing ... 2014 Morgan Stanley Global Healthcare Conference on Wednesday, September ... and Chief Executive Officer, will provide an update on ... (9:55 a.m., Pacific Daylight Time).   A ...
(Date:8/29/2014)...  BC Technical, the nation,s leading non-OEM provider of ... leader in sales, service and installation of GE MRI ... to continue to expand their resources and inventory while ... "We are committed to driving higher ... president and CEO of BC Technical. "We set out ...
Breaking Medicine Technology:Medina Medical Announces Erik T. Engelson Joins as Chief Executive Officer 2BC Technical Acquires Polaris Medical Imaging 2
... 2007 /PRNewswire-FirstCall/ -- On Wednesday,July 11, 2007, ... European Time members of Cell Therapeutics, Inc.'s ... to discuss today's,announcement of the interim results ... to CPOP-R, in which pixantrone is substituted ...
... in a physicians office practice, can be instrumental ... ailments; UTIs, diabetes, several cancers, metabolic disorders, cardiovascular ... for urinalysis tests is well in excess of ... For such a fundamental, extensive and economically significant ...
Cached Medicine Technology:Cell Therapeutics, Inc. Management to Discuss Today's Announcement,of Interim Pixantrone Study Results 2Urinalysis Analyzers: Large Capabilities in Every Size Device 2Urinalysis Analyzers: Large Capabilities in Every Size Device 3
(Date:8/29/2014)... review of clinical trials based on administering antidepressants ... concluded that more trials are needed to determine ... pain on a regular basis., Dr. Ian Gilron, ... in the Department of Anesthesiology, and his team ... whether the use of antidepressants for pain relief ...
(Date:8/29/2014)... by the Mental Health Commission of Canada identifies ... education that police personnel receive. , "People with ... police community, and today,s report builds on the ... with mental illnesses," says Queen,s adjunct professor Dorothy ... the area of police psychology. "This is a ...
(Date:8/29/2014)... US Preventive Services Task Force recommendations for screening and ... may be ameliorated through technological approaches according to a ... published online August 21, 2014 in the Journal ... David Levine, MD, MA, a third year resident in ... colleagues found that compared to usual care, technology-assisted interventions ...
(Date:8/29/2014)... New York, New York (PRWEB) August 29, 2014 ... died from cardiac arrest following a series of dialysis ... that alleges her death was the result of ... Liebhard LLP reports. The family’s lawsuit, which was file ... 2014, claims that the use of the products resulted ...
(Date:8/29/2014)... 29, 2014 A team of experts ... is on its way to the 2014 National Safety ... Convention Center to exhibit and demonstrate a suite of ... industrial environments. Etymotic’s safety earphones and high-definition earplugs are ... at the show. , The company’s HD5 high-definition, ...
Breaking Medicine News(10 mins):Health News:Antidepressants show potential for postoperative pain 2Health News:Report advocates improved police training 2Health News:Options for weight loss your primary care doctor might not know about 2Health News:GranuFlo Lawsuit News: Family Alleges Woman’s Death Following Dialysis Was Caused by GranuFlo and NaturaLyte, Bernstein Liebhard LLP Reports 2Health News:GranuFlo Lawsuit News: Family Alleges Woman’s Death Following Dialysis Was Caused by GranuFlo and NaturaLyte, Bernstein Liebhard LLP Reports 3Health News:GranuFlo Lawsuit News: Family Alleges Woman’s Death Following Dialysis Was Caused by GranuFlo and NaturaLyte, Bernstein Liebhard LLP Reports 4Health News:Etymotic’s Safe Listening Earphones and Earplugs Headed For The 2014 NSC Safety Expo 2
... Operating Cash Flow of $173 Million, and Generates $98 ... to Reflect Year-to-Date Sales Results, Maintains Bottom-Line GuidanceAUSTIN, Texas, ... WFMI ) today reported results for the 12-week ... the quarter were $1.9 billion, in line with the ...
... clinical trial led by Dr. Katherine Borden, at the ... the Universit de Montral, has shown that a common ... of cancer patients. Published in the journal Blood ... the activities of the eIF4E gene in patients. This ...
... American Pathologists today joined a lawsuit against the U.S. Patent and ... for the genes known as BRCA1 and BRCA2, which are indicators ... ... Washington, D.C. (Vocus) May 13, 2009 -- The College of ...
... the findings of a landmark drug comparison study published in ... other medications for high blood pressure. A scientific team including ... Houston reports the findings in the May 11 issue of ... in three adults in the United States has high blood ...
... be the newest "Biggest Loser" but she is a real ... is about simple, everyday choices that can help you be ... the glass and is one of the simplest things you ... and athletes to don a ,stache for the National Milk ...
... combination medication approved with the extended-release form of ... Takeda Pharmaceutical Company Limited and its wholly-owned subsidiary, ... announced that the U.S. Food and Drug Administration ... medication ACTO plus met(R) (pioglitazone HCl and ...
Cached Medicine News:Health News:Whole Foods Market Reports Second Quarter 2009 Results 2Health News:Whole Foods Market Reports Second Quarter 2009 Results 3Health News:Whole Foods Market Reports Second Quarter 2009 Results 4Health News:Whole Foods Market Reports Second Quarter 2009 Results 5Health News:Whole Foods Market Reports Second Quarter 2009 Results 6Health News:Whole Foods Market Reports Second Quarter 2009 Results 7Health News:Whole Foods Market Reports Second Quarter 2009 Results 8Health News:Whole Foods Market Reports Second Quarter 2009 Results 9Health News:Whole Foods Market Reports Second Quarter 2009 Results 10Health News:Whole Foods Market Reports Second Quarter 2009 Results 11Health News:Whole Foods Market Reports Second Quarter 2009 Results 12Health News:Whole Foods Market Reports Second Quarter 2009 Results 13Health News:Whole Foods Market Reports Second Quarter 2009 Results 14Health News:Whole Foods Market Reports Second Quarter 2009 Results 15Health News:Whole Foods Market Reports Second Quarter 2009 Results 16Health News:Whole Foods Market Reports Second Quarter 2009 Results 17Health News:Whole Foods Market Reports Second Quarter 2009 Results 18Health News:Whole Foods Market Reports Second Quarter 2009 Results 19Health News:Whole Foods Market Reports Second Quarter 2009 Results 20Health News:Whole Foods Market Reports Second Quarter 2009 Results 21Health News:Novel therapy may prove effective in treatment of 30 percent of cancers 2Health News:CAP Joins Landmark Lawsuit Challenging Legality of Myriad Genetics Gene Patents 2Health News:New research confirms milestone study on blood pressure meds 2Health News:New research confirms milestone study on blood pressure meds 3Health News:FDA Approves ACTOplus met(R) XR (pioglitazone HCl and metformin HCl extended-release) Tablets for the Treatment of Type 2 Diabetes 2Health News:FDA Approves ACTOplus met(R) XR (pioglitazone HCl and metformin HCl extended-release) Tablets for the Treatment of Type 2 Diabetes 3Health News:FDA Approves ACTOplus met(R) XR (pioglitazone HCl and metformin HCl extended-release) Tablets for the Treatment of Type 2 Diabetes 4
Clinical micro clamps by Acland. Matte finish. It provides impressive security in use, both against slippage and against leakage due to controlled closing force and working grip surface....
Micro emulsifying needles, 18G....
Micro 2000, micro scissors micro 2000 supercut....
Yasargil clip applying forceps Mini. Stainless steel jaw....
Medicine Products: