Navigation Links
Long-Term Phase I and Phase I/II Trial Data Continue to Show Striking Improvement in Survival of Brain Cancer Patients Who Receive DCVax(R)-Brain
Date:9/10/2008

BETHESDA, Md., Sept. 11 /PRNewswire-FirstCall/ -- Northwest Biotherapeutics, Inc. (OTC Bulletin Board: NWBO; AIM: NWBT and NWBS) ("NWBT" or the "Company") today announced the most recent long-term follow-up data, through June 15, 2008, from its prior Phase I and Phase I/II clinical trials with DCVax(R)-Brain, which began in 2000 and 2003, for patients with Glioblastoma multiforme, the most lethal type of brain cancer. This long-term data shows that 84% of patients who received DCVax(R)-Brain in these trials have so far lived longer than the median survival of 14.6 months under standard of care, 68% of the patients have so far lived more than 2 years, 58% of the patients have so far lived more than 2-1/2 years, 42% have so far lived more than 3 years, and 26% have so far lived more than 4 years, with patients surviving as long as 8 years to date. The median survival in the patients from these trials is now 36.4 months, under a standard Kaplan Meier analysis.

DCVax(R)-Brain is a groundbreaking personalized vaccine that takes a patient's own immune cells and trains them in the laboratory to attack the biomarkers from that patient's own tumor cells. The 10-day manufacturing process produces several years of personalized vaccine for a patient, making DCVax(R)-Brain an "off-the-shelf" product for that patient throughout the treatment period. DCVax(R)-Brain is administered as a simple injection under the skin, similar to a flu shot, and is not toxic as chemotherapies are.

The most recent data provides an update for the period since December 31, 2007, concerning both disease progression and overall survival. During that period, only one of the nineteen patients experienced disease progression (at 59.5 months), and only one patient died (at 37.8 months).

The long term data from these clinical trials shows that more than 80% of the patients who received DCVax(R)-Brain showed a clinical response. In contrast, the typical response rates for cancer dr
'/>"/>

SOURCE Northwest Biotherapeutics, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Medivation Presents Positive New Data on Dimebons Long-Term Efficacy and Novel Mechanism of Action at the International Conference on Alzheimers Disease
2. Precise Low-Dose Drug Monitoring Essential for Long-Term Kidney Transplant Success
3. Long-Term Pegylated Interferon Alfa-2b Therapy in Stage III Melanoma Demonstrated Significant and Sustained Impact on Relapse-Free Survival
4. Patients Own Infection-Fighting T Cells Put Late-Stage Melanoma Into Long-Term Remission - Without Chemotherapy or Radiation
5. Human Genome Sciences Reports Positive Long-Term Data for LymphoStat-B in Patients With Active Systemic Lupus Erythematosus
6. Pharmaxis Long-Term Safety Study of Bronchitol Completes
7. MultiVu Video Feed: Large, Long-Term Veterans Affairs Diabetes Trial (VADT) Reveals Important Cardiovascular Safety News on AVANDIA
8. Large, Long-Term Veterans Affairs Diabetes Trial (VADT) Reveals Important Cardiovascular Safety News on AVANDIA(R)
9. Long-Term Followup in Phase 3 CLL Trial Shows Genasense(R) is Associated with Significantly Increased Survival in All Responders
10. Abbott Presents Long-Term Data From Extension Study Showing Adult Crohns Patients Treated With HUMIRA(R) (Adalimumab) Maintained Remission
11. BARC Announces Long-Term Cooperation In South African Biobanking for HIV Vaccine Trials
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... 22, 2014  Edwards Lifesciences Corporation (NYSE: ... heart valves and hemodynamic monitoring, announced that Edwards, Chairman ... as an expert panelist at the invitation of the ... to discuss medical device innovation at its hearing, "21 ... Development and Communication." "Edwards has five decades ...
(Date:7/22/2014)... -- Jazz Pharmaceuticals plc (Nasdaq: JAZZ ) today ... financial results on Tuesday, August 5, 2014, after the ... a live audio webcast immediately following the announcement at ... and financial update and discuss second quarter 2014 financial ... audio webcast via the Investors & Media section of ...
(Date:7/22/2014)... , July 22, 2014 Research ... "Cell Culture Market by Equipment, by Reagent, by ... their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... organisms. Cell culture is one of the most important ... also the largest application segment of the cell culture ...
Breaking Medicine Technology:Edwards' CEO Invited To Address Congress On Opportunities To Revitalize Medical Device Innovation 2Jazz Pharmaceuticals to Report 2014 Second Quarter Financial Results on August 5, 2014 2Global Cell Culture (Bioreactor, Incubator, Centrifuge) Market - Forecast to 2018 2Global Cell Culture (Bioreactor, Incubator, Centrifuge) Market - Forecast to 2018 3
(Date:7/22/2014)... July 22, 2014 The 2014 ... the Ronald Reagan Building and International Trade Center ... Military Families and Civilian Communities,” will be held ... at 7:30 a.m.) and cohosted by the Military ... Defense Industrial Association (NDIA). USAA is the Executive ...
(Date:7/22/2014)... By Steven Reinberg ... -- Women who are obese during pregnancy may be more ... new review suggests. "We found that, compared with children ... overweight or obese during pregnancy had up to 20 to ... Erick Forno, an assistant professor of pediatrics at Children,s Hospital ...
(Date:7/22/2014)... of research at the University of Utah,s John A. ... Society of Eye Research (ISER) as the recipient of ... International Award in Retina Research., The award recognizes lifetime ... significant contribution to the understanding of vitreoretinal diseases or ... the ISER Biennial Meeting in San Francisco, where Marc ...
(Date:7/22/2014)... Washington DC (PRWEB) July 22, 2014 ... in USA, launched updated payment app for Forte Payment ... credit, debit and ACH payments on iPhone, iPod and ... 2013 and has been recently updated by SIMpalm. This ... support; app is currently supported on iOS 4.3 and ...
(Date:7/22/2014)... Ticket Down is a reliable source for ... in Landover, MD. There has never been a better time ... After the success of the American national soccer team at the ... One way that fans of the world’s sport will be able ... Guinness International Champions Cup. The tournament will kick off on July ...
Breaking Medicine News(10 mins):Health News:2014 Warrior-Family Symposium Focuses on Transitioning Forward 2Health News:2014 Warrior-Family Symposium Focuses on Transitioning Forward 3Health News:Obesity During Pregnancy Linked to Raised Asthma Risk in Kids 2Health News:Obesity During Pregnancy Linked to Raised Asthma Risk in Kids 3Health News:University of Utah researcher Robert Marc receives Paul Kayser International Award 2Health News:SIMpalm Launched Updated Forte Mobile Payment App on iPhone and iPad for Its Client 2Health News:SIMpalm Launched Updated Forte Mobile Payment App on iPhone and iPad for Its Client 3Health News:Manchester United vs. Inter Milan Tickets Fedex Field Landover: Ticket Down Slashes Ticket Prices for Inter Milan ManU International Champions Cup Match in Washington, DC 2Health News:Manchester United vs. Inter Milan Tickets Fedex Field Landover: Ticket Down Slashes Ticket Prices for Inter Milan ManU International Champions Cup Match in Washington, DC 3
... 9 Human Resources oversees an,organization,s biggest expense ... in some of a company,s biggest cost drivers, ... services can translate into significant,savings. To help ... LLC has published a comprehensive report containing more ...
... Day of Spa Services to Ten Breast Cancer Patients ... -Other Area Businesses Offer Freebies Too-, ... honor,of Breast Cancer Awareness Month, ten special breast cancer patients ... of luxurious spa,services for free. Afterward, the patients and their ...
... Oct. 9 Green Pet Products, an ... litter/bedding products,announces the development and introduction of ... products. (Photo: http://www.newscom.com/cgi-bin/prnh/20071009/CLTU089 ) ... content.,Addressing growing concerns over this microbiological content ...
... for Ozone Laundry and Energy Efficient Lighting Upgrades ... ... Oct. 9 National,Energy Services Company, Inc. (OTC Bulletin Board: NEGS), today ... and,Energy Efficient Lighting Upgrades. Golden Living skilled nursing,facilities in Indiana and California ...
... scientists, led by mathematicians, has taken on the challenge ... work will radically improve our understanding of the human ... on it to have a common reference point and ... Sciences Research Council (BBSRC), will investigate how the different ...
... COLUMBIA, Mo. Mr. Jones has chronic back pain. He ... because of the pain. He cannot lose weight because the ... in a publication by a University of Missouri-Columbia occupational therapy ... more than just a pill. , Some of the ...
Cached Medicine News:Health News:HR Under the Microscope: Metrics to Drive Costs Down Across HR Functions 2Health News:Breast Cancer Survivors Treated to a Day of Luxury for Breast Cancer Awareness Month 2Health News:Green Pet Products Introduces a New, Innovative Process to the Small Animal and Bird Litter/Bedding Category 2Health News:National Energy Services Receives Repeat Orders From Golden Living and Cathedral Rock Skilled Nursing Facilities 2Health News:Mathematicians help unlock secrets of the immune system 2Health News:More than a pill: Complementary medicine can help with chronic pain 2
Markham-Meyerding Hemilaminectomy Retractors, self-retaining, Right....
Panther Universal Spinal Retractor System...
Posterior Lumbar Retractor System ideally suited for spinal fixation, laminectomy, PLIF procedures. This system brings microdiscectomy to multi-level reconstruction....
... dense corticocancellous allografts comprised of ... structural integrity while allowing immediate ... allografts are available in Lordotic ... are processed from donor vertebral ...
Medicine Products: