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Lixte Biotechnology Holdings Announces Issuance of U.S. Patent for Agents for the Treatment of Neurodegenerative Diseases
Date:1/9/2012

EAST SETAUKET, N.Y., Jan. 9, 2012 /PRNewswire/ -- Lixte Biotechnology Holdings (OTC: LIXT.PK) announces that the United States Patent and Trademark Office awarded a patent for the use of lead compounds from each of two different types of drugs, protein phosphatase inhibitors and histone deacetylase inhibitors, for the potential prevention and treatment of neurodegenerative diseases.

Dr. John S. Kovach, founder and president of Lixte, said, "We have developed a series of novel compounds primarily as potential treatments for several common cancers as well as brain tumors of adults and children.  Some of these compounds, however, have been shown in laboratory studies to affect the biochemical status of human brain cells in ways believed to be beneficial to normal cell function and, unlike most potent anti-cancer drugs, appear to have tolerable toxicity in animals even when given for many days. We are looking to develop these compounds as neuroprotective agents of potential relevance to the prevention and treatment of a broad spectrum of neurodegenerative diseases, including acute neurological injury and chronic conditions such as Alzheimer's disease and Parkinson's disease.  Because Lixte is predominantly focused on developing anti-cancer drugs, we are interested in exploring licensing and/or partnerships for development of our lead compounds with companies having major programs in prevention and treatment of neurological illnesses."

About Lixte Biotechnology Holdings, Inc.

Lixte is a cancer drug discovery company, using biomarker technology and innovative chemistry to develop new potentially more effective anti-cancer drugs. It has lead compounds in two classes of drugs, protein phosphatase inhibitors for which a US patent was recently issued with world-wide patent applications pending for its lead compound LB-100 and structural variants , and novel histone deacetylase inhibitors for which broad patent applications are also pending.
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SOURCE Lixte Biotechnology Holdings, Inc.
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