Navigation Links
Liquid Tissue(R) Patent Licensed for Amyloidosis Proteomic Assay
Date:11/17/2009

ROCKVILLE, Md., Nov. 17 /PRNewswire/ -- Expression Pathology, a leader in tissue proteomic analysis, today announced Mayo Clinic has licensed non-exclusive rights to Expression Pathology's Liquid Tissue® patent for use in diagnosis of systemic amyloidosis in formalin-fixed tissue.

Patented Liquid Tissue® methodology enables solubilization of proteins for mass spectrometric analysis of formalin-fixed paraffin-embedded (FFPE) tissue, the standard form of preserved patient tissue used in clinical pathology testing worldwide. Mayo Clinic has applied the technology to develop a specific and sensitive mass spectrometry based method for diagnosis and classification of amyloidosis in routine biopsy specimens, in a format that is rapid and readily applicable in a clinical setting. This test is being offered to patients worldwide through Mayo Medical Laboratories, Mayo Clinic's reference laboratory.

With 50,000 diagnosed cases every year worldwide amyloidosis can be a localized or systemic disease, characterized by organ function impairment, sometimes as severe as cardiac and/or renal failure. Subtyping of cases is critical as management of the disease differs radically, from drug therapies to major organ transplants.

The new Liquid Tissue-based method aids in treatment decisions as it exhibits greater sensitivity and specificity than the traditional IHC based classification. In an early case study of 56 FFPE cardiac biopsies involving amyloidosis immunohistochemistry was diagnostic in 19/52 cases and equivocal in 33/52 cases (4 cases no IHC). The mass spectrometry-based Liquid Tissue method identified the amyloidosis type in 53 of 56 cases studied.

"Detailed mass spectrometry analysis of proteins related to specific disease conditions in FFPE tissue is opening huge opportunities in personalized medicine to relate those measurements to patient treatment decisions," said Casey Eitner, President and C
'/>"/>

SOURCE Expression Pathology Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Baxter and The Alzheimers Disease Cooperative Study Group to Pursue a Phase III Study of Gammagard Liquid in Patients With Alzheimers Disease
2. Baxter Presents Latest Clinical Trial Results of GAMMAGARD LIQUID Administered Subcutaneously
3. Study Results of GAMMAGARD S/D and GAMMAGARD LIQUID in Patients with Mild-to-Moderate Alzheimers Disease Announced
4. Advocate Christ Medical Center Using Glue-Like Liquid to Seal Off Brain Aneurysms
5. New Data Demonstrates 5-FU Personalized Chemotherapy Management (PCM(R)) Assay Provides Similar Performance to More Complicated Liquid Chromatography-Mass Spectrometry (LC-MS/MS)
6. NeurogesX Initiates Dosing in Phase 1 Clinical Trial for NGX-1998 Capsaicin Liquid Formulation
7. White Paper Explains Aspects of Testing From Purified Bulk Drug Substance to Sterile Liquid Final Drug Product
8. Xanodyne Expands U.S. Sales Force and Launches Zipsor(TM) (diclofenac potassium) Liquid Filled Capsules
9. Quark Pharmaceuticals Files Patent Application Covering Novel Chemical Modifications to its RNAi Molecules
10. ArtJen Announces Major Clinical Trial of Its Patented Weight Loss Product FBCx
11. FAU Receives Patent for Invention Which Induces and Restores Cardiac Muscle Function
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/16/2014)... , Sept. 16, 2014 ... of the "Global Laparoscopy Devices Industry Report ... The Global Laparoscopy Devices Industry Report 2014 ... current state of the global laparoscopic devices. ... the industry including definitions, classifications, applications and industry ...
(Date:9/16/2014)... 16, 2014 The National Association of ... simultaneously released the NAMCP Medical Technologies Dossier Template ... Template © , which provide medical directors and ... medical devices or diagnostics that accounts for evidence-based ... these technology types (instead of having to attempt ...
(Date:9/16/2014)... ORLANDO, Fla. , Sept. 16, 2014   ... standard in the patient experience at hospitals. The myComfort™ ... , Vestagen,s active barrier fabric that is fluid repellant, ... shown to inhibit the growth of bacteria on the ... the role clothing plays in the chain of transmission. ...
Breaking Medicine Technology:Global Laparoscopy Devices Industry Report 2014 2NAMCP Medical Directors Institute releases NAMCP Medical Technologies and Diagnostics Dossier Templates to provide model approach for medical devices or diagnostics 2New Vestagen Patient Garments Aim to Minimize Pathogen Transmission Inside Hospitals 2
... Med, the leading platform for automated revenue and charge ... the App Store for iPhone, iPod touch and iPad. ... company,s presence at the Hospital Information and Management Systems ... users to access the charge and data capture platform ...
... NexBio, Inc. announced the presentation of "Treatment of Parainfluenza ... Stem Cell Transplantation" at the American Society for Blood ... Honolulu, Hawaii.  The data was presented by Dr. Yi-Bin Chen, ... Medical School. Parainfluenza virus (PIV) infection causes ...
Cached Medicine Technology:HIMSS11: Ingenious Med Launches Billing and Data Capture App for iPhone, iPod touch and iPad 2NexBio’s DAS181 (Fludase®*) Improved Symptoms in a Severely Immunocompromised Patient with Parainfluenza Pneumonitis 2NexBio’s DAS181 (Fludase®*) Improved Symptoms in a Severely Immunocompromised Patient with Parainfluenza Pneumonitis 3
(Date:9/16/2014)... Kathleen Doheny HealthDay ... A simple urine test can routinely spot human papillomavirus (HPV), ... new analysis found. "Our study shows that testing urine ... taken from the cervix for HPV," said lead researcher Dr. ... and research fellow at Queen Mary University of London, England. ...
(Date:9/16/2014)... MN (PRWEB) September 16, 2014 Cliff Lake ... their team. Kristaleen is the newest dental hygienist to join ... looks forward to working with her and knows she will ... her patients. , Kristaleen grew up in River Falls, WI. ... County Technical College in 2003 and practiced dental assisting in ...
(Date:9/16/2014)... CO (PRWEB) September 16, 2014 Aspen ... that it has been recognized for its high morale ... Consulting magazine “The Best Small Firms to Work For ... survey annually, with more than 10,000 consultants participating across ... Extensive employee satisfaction surveys were conducted, and firms were ...
(Date:9/16/2014)... Treatment with endocrine therapy and radiation therapy as ... of care for women with hormone-receptor positive (HR+) ... at Fox Chase Cancer Center, however, shows that ... populations with the disease. , The results, ... Society for Radiation Oncology,s 56th Annual Meeting on ...
(Date:9/16/2014)... York, NY (PRWEB) September 16, 2014 ... children around the world will be honored in New ... Award ( http://www.worldofchildren.org ), the only global recognition and ... , Hailed by the media as the “Nobel ... individuals have each created life-changing programs that benefit children ...
Breaking Medicine News(10 mins):Health News:Urine Test for HPV Works Well, Analysis Finds 2Health News:Cliff Lake Dental Care Announces Newest Team Member 2Health News:Aspen Advisors Earns Recognition in Consulting Magazine’s "Best Small Firms to Work For" 2Health News:Aspen Advisors Earns Recognition in Consulting Magazine’s "Best Small Firms to Work For" 3Health News:Benefit of endocrine therapy in elderly women with low risk hormone receptor positive breast cancer? 2Health News:Benefit of endocrine therapy in elderly women with low risk hormone receptor positive breast cancer? 3Health News:World of Children® Award Announces 2014 Honorees 2Health News:World of Children® Award Announces 2014 Honorees 3Health News:World of Children® Award Announces 2014 Honorees 4Health News:World of Children® Award Announces 2014 Honorees 5Health News:World of Children® Award Announces 2014 Honorees 6Health News:World of Children® Award Announces 2014 Honorees 7Health News:World of Children® Award Announces 2014 Honorees 8
... inventor,of Pulse CO-Oximetry and Read-Through Motion and Low Perfusion ... at the Piper,Jaffray 19th Annual Healthcare Conference at The ... 2007 at 8:30 a.m. ET. Joe Kiani, Chairman and,CEO, ... will be,presenting. A live Web cast of the ...
... to 60%, study found , THURSDAY, Nov. 15 (HealthDay News) ... oils, fruits and vegetables may reduce the risk of dementia ... may boost the risk of developing memory problems, say French ... people older than 65 who did not have dementia at ...
... a 150 percent increase between 1998 and 2003 in ... cancer has been found in only one breasta procedure ... study to examine these trends on a national level. ... unnecessary since most patients will never develop cancer in ...
... Just and Stanford postdoctoral fellow Sashank Varma have put ... provides answers to one of the central questions of ... to give rise to complex cognitive tasks such as ... theory, called 4CAPS, is described in the fall issue ...
... Proceeds from the Mural will Benefit St. Jude Children,s Research ... Jude Thanks and Giving Campaign, Event to be ... at Bryant Park, NEW YORK, Nov. 15 Visitors ... become artists for a day, as they,help put the finishing ...
... ... Affordable Program Company Provides Upscale ... the leading meal,delivery service provider based on the Dr. Sears, Zone Diet ... that provides,chef-prepared, gourmet frozen meals for as low as $9.99 per day*. ...
Cached Medicine News:Health News:Masimo to Present at Piper Jaffray 19th Annual Healthcare Conference 2Health News:Fish, Fruits, Veggies May Cut Dementia Risk 2Health News:More women are choosing double mastectomy even when breast cancer is confined to a single breast 2Health News:Carnegie Mellon neuroscientist proposes new theory of brain flexibility 2Health News:Carnegie Mellon neuroscientist proposes new theory of brain flexibility 3Health News:American Airlines Invites the Public to Join Marlo Thomas and St. Jude Patients to Create One-of-a-Kind Mural to Celebrate 80 Years of Service in the Greater New York Area 2Health News:American Airlines Invites the Public to Join Marlo Thomas and St. Jude Patients to Create One-of-a-Kind Mural to Celebrate 80 Years of Service in the Greater New York Area 3Health News:American Airlines Invites the Public to Join Marlo Thomas and St. Jude Patients to Create One-of-a-Kind Mural to Celebrate 80 Years of Service in the Greater New York Area 4Health News:CHEFS DIET(R) Introduces My Solution 2
Featuring a secure and tamper-evident adhesive closure, computer-generated Smart ScanBand can be simultaneously printed with bar code information and programmed with RFID information....
Safe. Reliable. Baby-friendly. ,The Hugs infant protection system helps to protect your infants and children from the threat of abduction....
VerdaSee Portal ID is a family of solutions that provide automated tracking and tracing of assets as they enter or leave designated areas within a healthcare facility....
... Agility is positioned to support ... to reduce medication and other ... workflow for pharmacy support staff ... blood products, lab specimens and ...
Medicine Products: