RALEIGH, N.C., June 23, 2013 /PRNewswire/ -- LipoScience, Inc. (NASDAQ: LPDX), a diagnostic company pioneering a new field of personalized nuclear magnetic resonance (NMR) diagnostics to advance the quality of patient care in cardiovascular, metabolic and other diseases, today announced the presentation of data at the 73rd Scientific Sessions of the American Diabetes Association (ADA) from June 21-25 in Chicago, Ill.
During a poster presented Sunday, June 23 at 11:30 a.m. CT, researchers from Duke University Medical Center demonstrate that the novel Lipoprotein Insulin Resistance score (LP-IR), which was developed by LipoScience, is a potentially clinically useful and convenient index of insulin resistance.
"Insulin resistance is accompanied by alterations in lipoprotein metabolism that result in distinct changes in the lipoprotein profile detected by NMR," explained lead investigator William Kraus, M.D, Professor of Cardiology at Duke University and an author of the study. "These data support the LP-IR score, which combines six lipoprotein subclasses and size variables into a single parameter that could serve as a surrogate marker of insulin resistance."
Dr. Kraus and colleagues compared the LP-IR score, with values ranging from 0 (most insulin-sensitive) to 100 (most insulin-resistant), to two standard measures of insulin resistance – one derived from intravenous glucose tolerance tests and the other from the homeostatic model assessment of insulin resistance (HOMA-IR) – in two distinct cohorts of overweight and obese adults. The researchers concluded that the LP-IR score may provide a particularly efficient and effective way to identify insulin-resistant patients who are at increased risk of developin
|SOURCE LipoScience, Inc.|
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