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Lilly to Acquire Alnara Pharmaceuticals
Date:7/2/2010

to Alnara Pharmaceuticals.

"The acquisition of Alnara provides Lilly with a promising entry into enzyme replacement therapy -- an area with unmet medical needs as well as opportunities for novel compounds that give patients additional treatment options," said Bryce Carmine, executive vice president of Lilly and president of Lilly BioMedicines. "Alnara has been very successful in the development of liprotamase -- as indicated by its recent submission to the FDA -- and we look forward to partnering with Alnara's experts during the regulatory review process."

Alexey Margolin, Ph.D., chief executive officer of Alnara, said: "Our agreement with Lilly is an important development as we move liprotamase through FDA regulatory review. Lilly's deep expertise in the U.S. pharmaceutical business, including regulatory affairs and the development of innovative compounds that address unmet medical needs, created a natural fit and could allow for opportunities in markets beyond cystic fibrosis. We look forward to finalizing the transaction and working together on next steps to bring liprotamase to patients."

If approved, liprotamase will allow many patients to use significantly fewer pills compared to current treatment options. Treatments in the PERT class reduce malabsorption and enhance nutrition in patients with EPI. Because it is not derived from a porcine source, liprotamase could provide the added benefit for patients of reduction in the risk of viral exposure. A pediatric formulation of liprotamase also is in development.

About Liprotamase & Pancreatic Enzyme Replacement Therapy (PERT)

Liprotamase is an oral, non-porcine pancreatic enzyme replacement therapy designed to treat maldigestion, malabsorption and malnutrition as a result of exocrine
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SOURCE Eli Lilly and Company
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