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Lilly and New York City Mayor Michael R. Bloomberg Announce Lilly Agrees to be First Tenant of East River Science Park; Issue Urgent Call for Healthcare Reform that Protects Innovation and Jobs
Date:7/22/2009

. There is an urgent need for medication that can do more than simply cloak the effects of this disease."

Continuing Innovation Critical

When it moves to the new East River Science Park, which is expected to open sometime in the summer of 2010, ImClone will have access to a state-of-the-art facility for conducting its innovative research. ImClone's Research group conducts the preclinical discovery efforts that have produced the clinical product candidates in ImClone's robust pipeline of therapeutic antibodies. The new location will help expand collaborative activities with local academic institutions as ImClone further accelerates its research to add new molecules to its pipeline. In addition to the second Phase III trial of IMC-1121B announced today, ImClone has made several advancements in its pipeline since being acquired by Lilly. Highlights include:

  • IMC-11F8 is expected to move into Phase III development by the end of 2009;
  • Phase II testing of IMC-A12 has been expanded to include colorectal, neuroendocrine and lung cancers. Phase III studies of IMC-A12 are expected to begin in either late 2009 or early 2010;
  • IMC-3G3 has recently moved into Phase II development with a study in ovarian cancer, and additional Phase II studies in other tumor types are planned;
  • Phase II studies of IMC-1121B have been expanded to include colorectal cancer;
  • The first Phase I trial of IMC-EB10, in leukemia, was recently launched, increasing the number of ImClone molecules in clinical development to six; and
  • ImClone also expects to file at least one new investigational new drug (IND) application by the end of 2009.

According to Lilly Chairman, President and CEO John Lechleiter, Ph.D., "Having six monoclonal antibodies contributed by ImClone to the Lilly oncology portfolio is a great step toward achievement o
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SOURCE Eli Lilly and Company
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