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Lilly and New York City Mayor Michael R. Bloomberg Announce Lilly Agrees to be First Tenant of East River Science Park; Issue Urgent Call for Healthcare Reform that Protects Innovation and Jobs
Date:7/22/2009

iatives to promote entrepreneurship, develop green jobs, support nonprofits, grow the media industry and add industrial jobs, and today's announcement affirms our belief that bioscience is another industry in which the City can and will succeed."

As further evidence of innovation, Lilly also said that it now has six ImClone molecules in its pipeline, bringing the company's total number of oncology molecules in clinical development to 23 and the number of unique investigational medicines in the Lilly pipeline to 66. ImClone has achieved several important milestones in advancing its pipeline of novel antibodies since being acquired by Lilly less than a year ago. One of those molecules, IMC-1121B, already in Phase III development for breast cancer, will be evaluated in another Phase III trial, this time for gastric cancer.

The purpose of the Phase III gastric cancer study is to evaluate the effect of IMC-1121B on the overall survival of patients with metastatic gastric cancer following disease progression on standard first-line chemotherapeutic regimens. This pivotal trial will be conducted at approximately 250 academic research centers across five continents.

"This is an important milestone for us as we work to develop innovative therapies to treat patients with cancer," said ImClone's Chief Medical Officer Eric K. Rowinsky, M.D. "Gastric cancer is not only a major cause of mortality and morbidity in Asia, but the incidences of certain types of gastric malignancies such as gastro-esophageal junctional cancer, which will also be evaluated in our study, are increasing in North America, Europe and outside of Asia. Gastric cancer is diagnosed more than 21,000 times each year in the United States alone and is the second leading cause of cancer death worldwide, with more than 800,000 deaths annually. Current medical techniques for the treatment of gastric cancer are primarily palliative rather than curative
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SOURCE Eli Lilly and Company
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