Navigation Links
Lilly and Argonne National Laboratory Announce $2 Million Upgrade to Lilly's Beamline Capabilities
Date:7/14/2011

funded by Lilly and supports LRL's objective of producing more "timely shots in goal," in other words, getting medicines approved and available as quickly as possible to the patients who are waiting.

A simple way to think about the work Lilly scientists are conducting at its beamline facility is to view the disease protein they are studying as the "lock" and the molecule as the "key." The beamline helps researchers determine if the molecule (the key) can unlock the protein disease target (the lock) and therefore change its behavior.

To do this, Lilly chemists typically develop large numbers of molecules (keys) and add the molecules to the protein disease target (locks), developed by Lilly structural biologists, to create protein crystals. Once this process is complete, the crystals are sent to the LRL-CAT beamline facility via overnight delivery for analysis. The LRL-CAT beamline utilizes x-rays to determine if and how the molecule was able to "unlock" the protein, usually within minutes of acquisition. Based on the results from the data, Lilly scientists are able to quickly create better "keys." The facility currently examines more than 10,000 protein crystals per year and supports nearly half of Lilly's research portfolio.

"Utilizing the team and beamline at Argonne to develop potential medicines to treat diseases like Alzheimer's is a great example of technology and the human mind coming together. Lilly scientists utilized beamline data to help design our beta-secretase inhibitor which is currently in Phase I clinical testing to determine its potential as a treatment for Alzheimer's disease. In this specific instance they have come together literally to learn to save the human mind," said Jan Lundberg, Ph.D., executive vice president, science and technology, and president, Lilly Research Laboratories.

"The APS has long been a hotspot of pharmaceutical research and has become an increasingly important tool for Lilly and other pharmaceu
'/>"/>

SOURCE Eli Lilly and Company
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. FDA Approves Lillys Osteoporosis Drug EVISTA(R) (raloxifene HCl) to Reduce The Risk of Invasive Breast Cancer in Two Populations of Postmenopausal Women
2. Lilly Files for European Approval of ALIMTA(R) (pemetrexed for injection) for First-Line Treatment of Non-Small Cell Lung Cancer
3. Lilly and Glenmark Pharmaceuticals Announce License Agreement
4. Lilly Receives NCQA Design Certification for Depression Care Management Program
5. JDRF and Lilly Partner to Fund Research to Identify Beta Cell Biomarkers
6. FDA Grants Priority Review for Daiichi Sankyo, Lilly Drug, prasugrel
7. Statement from Eli Lilly and Company: Response to Connecticut Attorney General News Release
8. Lilly and Transition Therapeutics Announce Licensing and Collaboration Agreement
9. Lilly Launches Its First Phase III Trial for Treatment of Alzheimers Disease
10. Daiichi Sankyo/Eli Lillys Effient and Astrazenecas Ticagrelor May Offer Advantages in the Treatment of Post-Myocardial Infarction
11. Lilly Submits Cymbalta(R) Supplemental New Drug Application for Chronic Pain to U.S. Food and Drug Administration
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... BURLINGTON, Mass. , Aug. 20, 2014 ... Japanese electrophysiology (EP) mapping and ablation device ... increasingly use ablation to treat atrial fibrillation ... a primary treatment option for AF will ... for this application, such as advanced loop ...
(Date:8/20/2014)... LAKE CITY , Aug. 20, 2014 ... revolutionary mobile diagnostic platform during a special event at ... Utah , on September 5, 2014. The event, ... LiveStreamed on the ApolloDx website, www.apollodx.com .    ... transform diagnostic testing," said Jared Bauer , Co-Founder ...
(Date:8/20/2014)... Aug. 20, 2014 Reportlinker.com announces that ... its catalogue: The Market for Medical ... The European, Middle Eastern and African markets ... As part of its coverage, this study: The ... the EMEA medical device markets and estimates markets ...
Breaking Medicine Technology:Electrophysiology Mapping and Ablation Device Market in Japan to Reach $1.1 Billion by 2023 2Electrophysiology Mapping and Ablation Device Market in Japan to Reach $1.1 Billion by 2023 3The Market for Medical Devices in EMEA 2The Market for Medical Devices in EMEA 3The Market for Medical Devices in EMEA 4The Market for Medical Devices in EMEA 5
... YORK, Pa., Nov. 15, 2011 Unilife Corporation (NASDAQ: ... that it has commenced an underwritten public offering of shares of ... be sold by Unilife. The offering is subject to market conditions, ... the offering may be completed, or as to the actual size ...
... 14, 2011, DHS Holding Co. (DHS) issued a press ... Radient Pharmaceuticals Corporation (OTCQX:RXPC) (OTCPK:RXPC), to discuss business opportunities ... was issued without our approval and we do not ... any business opportunities with DHS. On ...
Cached Medicine Technology:Unilife Corporation Announces Proposed Public Offering of Common Stock 2Unilife Corporation Announces Proposed Public Offering of Common Stock 3Radient Pharmaceuticals Asks DHS Holding Co. to Retract News Release Saying It Will Enter Into Talks With Radient Pharmaceuticals Corporation 2
(Date:8/20/2014)... Little Green Pouch today announced the ... Pouch —to meet growing demand for eco-friendly products that ... foods. , “The Real Food movement is really ... She continues, “Parents want to choose exactly what ... like pesticides and hidden ingredients in commercially prepared foods. ...
(Date:8/20/2014)... 2014 One Call Alert expands its line ... ResCube, a fully-mobile wearable device that connects customers to the ... 24 hours a day, 365 days a year. , ResCube ... country. It operates on the T-Mobile nationwide network like a ... to work. , Like with the other One Call Alert ...
(Date:8/20/2014)... "I decided that there needed to be a ... without the hassles associated with using conventional oral devices," ... DR. GATES ORAL-HYGIENE TOOL provides an easy way to ... oral hygiene and fresh breath, and it eliminates the ... eco-friendly and easy to use, the device is producible ...
(Date:8/20/2014)... car at home and getting to work by walking, cycling ... study indicates. Researchers looked at thousands of people in ... and 72 percent of women drove to work, 10 percent ... and 14 percent of men and 17 percent of women ... more and had higher levels of body fat than those ...
(Date:8/20/2014)... has been chosen by Plymouth University to be an ... April 2009 to raise awareness of, and funding for, ... brain tumour patients. , A range of events and ... the charity, and members of staff and students, as ... donate, fundraise and volunteer. The involvement of the wider ...
Breaking Medicine News(10 mins):Health News:Little Green Pouch Launches New Product to Help Health-conscious Parents Reduce Babies’ Eco-footprint 2Health News:One Call Alert Introduces ResCube™, Smallest Mobile Medical Alert System on Market 2Health News:One Call Alert Introduces ResCube™, Smallest Mobile Medical Alert System on Market 3Health News:Want to Stay Slim? Leave the Car at Home 2Health News:Plymouth University chooses Brain Tumour Research as official charity 2
... ... ... Wood Johnson Foundation ® (RWJF) announced today the launch of a new Web site - ... on the programs in the RWJF Human Capital Portfolio., , ,“This new Web site brings ...
... ... ... ... ...
... ... Dishes , ... AR (PRWEB) March 1, 2010 -- Sam’s Club expands its wine offerings this month ... variety is the basis of Infinite, complemented by a small proportion of Cabernet Sauvignon. ...
... , ... ... ... , ...
... specially modified contrast agents may allow researchers to noninvasively ... published in the March issue of The Journal ... enables researchers to visualize tumor activity at the molecular ... for the early detection of disease," said Juergen K. ...
... behavior of the seasonal form of the H1N1 influenza virus ... most strains of the pandemic H1N1 flu virus will become ... it. Researchers at Ohio State University have traced the ... infected humans during the 1918 pandemic. It is one of ...
Cached Medicine News:Health News:Robert Wood Johnson Foundation Launches New Scholars, Fellows & Leadership Programs Web Site 2Health News:Robert Wood Johnson Foundation Launches New Scholars, Fellows & Leadership Programs Web Site 3Health News:Rhoads Named Director of Cancer Outreach Programs For Stanford Cancer Center, Cancer Prevention Institute of California 2Health News:Rhoads Named Director of Cancer Outreach Programs For Stanford Cancer Center, Cancer Prevention Institute of California 3Health News:Rhoads Named Director of Cancer Outreach Programs For Stanford Cancer Center, Cancer Prevention Institute of California 4Health News:Rhoads Named Director of Cancer Outreach Programs For Stanford Cancer Center, Cancer Prevention Institute of California 5Health News:Rhoads Named Director of Cancer Outreach Programs For Stanford Cancer Center, Cancer Prevention Institute of California 6Health News:Put Some Fiesta Into Dinner - Sam's Club Adds New Spanish Red Wine From Torres Winery 2Health News:Torchmark Corporation Elects New Director 2Health News:The proof's in the bubbles 2Health News:Pandemic flu, like seasonal H1N1, shows signs of resisting Tamiflu 2Health News:Pandemic flu, like seasonal H1N1, shows signs of resisting Tamiflu 3Health News:Pandemic flu, like seasonal H1N1, shows signs of resisting Tamiflu 4
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: