Lilly Submits Cymbalta(R) Supplemental New Drug Application for Chronic Pain to U.S. Food and Drug Admi...(A. For full Prescribing Information i...),Health

For full Prescribing Information, including Boxed Warning and medication guide, visit http://www.cymbalta.com/.

About Eli Lilly and Company

Lilly, a leading innovation-driven corporation, is developing a growing portfolio of first-in-class and best-in-class pharmaceutical products by applying the latest research from its own worldwide laboratories and from collaborations with eminent scientific organizations. Headquartered in Indianapolis, Ind., Lilly provides answers -- through medicines and information -- for some of the world's most urgent medical needs. Additional information about Lilly is available at http://www.lilly.com.

P-LLY

This press release contains forward-looking statements about the potential of Cymbalta for the management of chronic pain, and reflects Lilly's current beliefs. However, as with any pharmaceutical product, there are substantial risks and uncertainties in the process of development and commercialization. There is no guarantee that the product will receive regulatory approval for chronic pain, or that it will continue to be commercially successful. For further discussion of these and other risks and uncertainties, see Lilly's filings with the United States Securities and Exchange Commission. Lilly undertakes no duty to update forward-looking statements.

(i) International Association for the Study of Pain. "IASP Pain Terminology" Available at: http://www.iasp- pain.org/AM/Template.cfm?Section=General_Resource_Links&Template=/CM/HTMLDi spl ay.cfm&ContentID=3058#Pain. Accessed on 5/27/08.

(ii) American Pain Society. "Pain Control in the Primary Care Setting." 2006:15.

(Logo: http://www.newscom.com/cgi-bin/prnh/20031219/LLYLOGO)