Lilly TB Drug Discovery Initiative
The Lilly TB Drug Discovery Initiative was created in 2007 to accelerate early stage drug discovery by bringing together specialists from around the world for the systematic exploration of vast, private molecular libraries in search of new TB treatments.
Located within IDRI's base in Seattle, the Lilly TB Drug Discovery Initiative involves representatives of government agencies, philanthropic organizations, pharmaceutical companies, universities, and other research institutions. Its most important goal is filling the pipeline with future TB drugs.
Lilly provided $15 million to launch and support the effort for a five-year period. Included in Lilly's initial funding was $9 million in-kind – including fully equipped high-throughput screening and chemistry laboratories, research tools, and scientific and technical expertise – plus $6 million in cash to seed the organization. In addition to this initial funding, Lilly provided access to a library of compounds – which has now grown to more than 800,000 compounds.
Today's announcement of an additional $4.2 million in funding will allow IDRI to further its early phase drug discovery efforts focused on TB and MDR-TB through 2016.
Steven Reed, president, chief scientific officer and founder of IDRI said, "We are excited that Lilly is extending its support of our TB drug discovery program. It's a real vote of confidence in the quality of our scientists' work and the productivity of our collaborations."
Lilly's Evolving Role in the Fight against TB
In 1996, the nonprofit organization Partners in Health began pioneering work that demonstrated cure rates of more than 80 percent could be achieved for patients with MDR-TB using several drugs, including two Lilly antibiotics that the company had planned to stop manufacturing.
Lilly began offering the two
|SOURCE Eli Lilly and Company|
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