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Lilly CEO Lechleiter Calls for Repair of the 'Engine of Biopharma Innovation'
Date:10/30/2009

s the industry must overcome:

  • A loss of trust in product safety and in the honesty of pharmaceutical businesses, for which he said "we mostly have ourselves to blame";
  • A risk-averse policy and regulatory environment that has led to high hurdles for new medicines that could benefit patients; and
  • The pressures of the health care system, where the industry has become an attractive target for policy makers looking for cost savings, even as prescription drugs account for only 10 percent of health care spending.

Lechleiter said that instead of wasting time complaining about these external pressures, however, biopharma companies must change the way they develop new medicines.

He suggested three "C's" for revitalizing medical innovation:

  • Collaboration: breaking down the walls to work with other large and small enterprises and with academic and government researchers, worldwide;
  • Competency: employing advanced scientific tools to take advantage of the explosion of knowledge in human biology; and
  • Culture: putting patients and improved outcomes at the center of research from the very beginning of the drug development process.

Lechleiter cited Lilly initiatives in each area:

  • Lilly's Fully Integrated Pharmaceutical Network (FIPNet) model to access ideas, resources, and talent beyond its walls, including extensive collaboration with biotech firms and academic research centers in San Diego;
  • The company's use of advanced analytics and clinical trial designs, and its new Development Center of Excellence, to streamline the development of new medicines, and its focus on tailored therapeutics to improve outcomes for individual patients; and
  • Lilly's efforts to create a culture with a sharp focus on patients and a "new spirit of urgency."

He concluded that reinventing biopharmaceutical research and development in thes
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SOURCE Eli Lilly and Company
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