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Lilly, Kowa and Kowa Pharmaceuticals America Announce Co-Promotion and Licensing Agreement
Date:12/23/2009

considered:

  • the AIDS drugs, lopinavir and ritonavir. LIVALO should not be used with this drug combination,
  • the antibiotics, erythromycin and rifampin. A LIVALO dose reduction may be indicated.
  • the cholesterol drugs, fibrates and niacin. A LIVALO dose reduction may be indicated.

While taking LIVALO, the patient should be advised not to start taking any of these medicines without speaking to their doctor or pharmacist first. Additional drug-drug pharmacokinetic interaction studies were conducted; the results of these studies are tabulated in the full prescribing information.

PATIENT COUNSELING INFORMATION

The patient should be informed of the following:

Dosing Time: LIVALO can be taken at any time of day with or without food.

Muscle Pain: Patients should be advised to promptly notify their physician of any unexplained muscle pain, tenderness, or weakness. They should discuss all medication, both prescription and over the counter, with their physician.

Pregnancy: Women of childbearing age should use an effective method of birth control to prevent pregnancy while using LIVALO. Discuss future pregnancy plans with your healthcare professional, and discuss when to stop LIVALO if you are trying to conceive. If you are pregnant, stop taking LIVALO and call your healthcare professional.

Breastfeeding: Women who are breastfeeding should not use LIVALO. If you have a lipid disorder and are breastfeeding, stop taking LIVALO and consult with your healthcare professional.

Liver Enzymes: It is recommended that liver enzymes be checked before and at 12 weeks following both the initiation of therapy and any elevation of dose, and periodically (e.g., semiannually) thereafter.

For complete product prescribing information you should consult the current LIVALO (pitavastatin) package
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SOURCE Eli Lilly and Company
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