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LigoCyte Pharmaceuticals Initiates a Randomized, Double Blind, Placebo Controlled Norovirus Vaccine Study Including Live Virus Challenge
Date:9/8/2009

free, dry powder formulation based on virus like particle (VLP) antigens, which are highly purified protein products. By preserving the authentic conformation of the viral capsid, VLPs mimic the antigen presentation of the live virus while lacking the ability to reproduce or cause illness. LigoCyte's vaccine formulation also includes the adjuvant Monophosphoryl Lipid A, provided under license from GlaxoSmithKline (NYSE: GSK), and chitosan (ChiSys(R)) to enhance nasal delivery, under license from Archimedes Development Ltd. LigoCyte's challenge study will utilize a live Norwalk virus inoculum developed at Baylor College of Medicine with funding from the National Institutes of Health. Additional information about the study can be found at www.clinicaltrials.gov.

On September 9, 2009, Marcelo Sztein, M.D., Professor of Pediatrics and Medicine at the Center for Vaccine Development at the University of Maryland School of Medicine, will present safety and immunogenicity data on LigoCyte's norovirus vaccine at the 5th International Conference on Vaccines for Enteric Diseases (VED2009) in Malaga, Spain. Dr. Sztein's oral presentation will include clinical data on safety of the vaccine as well as serum immunoglobulin levels (IgG and IgA) resulting from vaccination.

About LigoCyte:

LigoCyte is an immunology company developing a new generation of vaccines for the prevention of infectious diseases. LigoCyte's expertise in virus-like particle vaccines supports a pipeline of enhanced products, including vaccines against norovirus, influenza and respiratory syncytial virus. The company is also developing antibody therapeutics against important chronic inflammatory diseases. For additional information on L
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SOURCE LigoCyte Pharmaceuticals, Inc.
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