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Life Technologies and SATuRN Collaborate to Increase Access to HIV Testing in Africa
Date:7/24/2012

CARLSBAD, Calif., July 24, 2012 /PRNewswire/ -- Life Technologies Corporation (NASDAQ: LIFE ) today announced a collaboration with the Southern African Treatment and Resistance Network (SATuRN – http://www.bioafrica.net/saturn) on sequencing-based diagnostics for HIV-infected individuals in Africa.

Antiretroviral (ARV) drugs are becoming increasingly available in the developing world, due to facilitation by both governmental and non-governmental organizations, as well as reductions in price and international trade restrictions by pharmaceutical companies. Resistance to these drugs develops in many HIV-infected individuals, however, and resistance is therefore coming to the forefront of the global health agenda. Resistance can be monitored by genetic sequencing of two viral genes, but current costs have made routine use prohibitive in most African countries.

Life Technologies has developed together with SATuRN a simple-to-answer solution for ARV resistance testing, which is being made available to African partners at a highly economic cost per test. The test can be run on Life's Applied Biosystems line of Sanger sequencing instruments, which are broadly installed in African hospitals and HIV-testing centers.

The methods developed as part of this collaboration have the potential to become the most accurate and cost-effective method for the diagnosis of resistance pathogens in Africa and the referral of patients for appropriate care.  The reasons for this are that the price of DNA/RNA genotyping is rapidly decreasing as technology is evolving at great speed, and the software applications to be used and further developed are all open source and available in Africa (Dr. Tulio de Oliveira on behalf of SATuRN - Public HIV Drug Resistances Databases in Africa, published in the journal NATURE 2010).

"Drug resistance testing is an essentia
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SOURCE Life Technologies Corporation
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