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Life Technologies Launches GeneArt® Precision TALs
Date:3/19/2012

simple TAL effector translation code allows researchers to specifically design TAL binding proteins to bind to a DNA sequence of choice. 

"Researchers give us the sequence they want to target, and we send them a gene encoding the TAL protein that will target it," said Wood. "The encoding process is that simple."

"TAL effectors have been evolved with beautiful simplicity," said Jens Boch, co-inventor of TAL technology. "We can now harness their natural properties to make a unique tool that represents a giant leap for genome editing and other applications."

GeneArt® Precision TALs are supplied as Gateway® compatible entry clones encoding a DNA binding protein for a specific customer-submitted sequence fused to a range of customer selected effector domains. Custom TALs will typically be delivered in 3 weeks after orders are placed.

The current offering includes TALs fused with gene activators, endonucleases or a vector with multiple cloning sites providing customers the ability to link their own functional domain proteins to the TAL protein, constituting a system that is easily customized to each researcher's needs. A TAL offering with a gene repression domain will be released at a future date.

The TAL Effector Technology license was jointly signed with inventors Boch, Ulla Bonas, Thomas Lahaye and Sebastian Schornack based from seminal discovery work while at Martin-Luther-Universitat Halle-Wittenberg, and with Two Blades Foundation (2Blades), which exclusively licensed plant research tool uses to Life Technologies and retains exclusive rights for commercial applications in plants.

For more information, please visit www.lifetechnologies.com/TAL

All products referenced are for Research Use Only. Not intended for diagnostic uses.

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SOURCE Life Technologies Corporation
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