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Life Technologies Consortium to Create New Frontline Diagnostic Utilising DNA Sequencing for Cancer Patients in the U.K.
Date:6/22/2011

ts. We believe that the best way for this to happen is if we can demonstrate a consolidated, quality assured sample collection and testing network covering the main biomarkers for existing and future therapies. By proving that this can work in the NHS, we can make sure that all doctors can access the right tests."

The new multi-gene NGS test developed by Life Technologies will be made available to Cancer Research UK Stratified Medicine laboratories in early 2012, for comparison with existing testing methodologies.  The Life Technologies programme fits with the Cancer Research UK Stratified Medicine by developing the test, while Cancer Research UK Stratified Medicine will demonstrate the operational model to deliver these tests in the NHS.

1,500 patient program at Oxford will report expanded panel of 150 genes selected by researchers and pharmaceutical partners

Beginning in 2012, the Oxford BRC will be conducting a 1,500 patient prospective clinical trial that will measure and report on an expanded panel of 150 genes selected by researchers and pharmaceutical partners. Oxford's clinical trial will utilise Life Technologies' multi-gene NGS test. Through review of these study results, physicians may be able to identify alternative care options for their patients, and be able to recommend suitable drug trials taking place in the Oxford system.  

"The current system for clinical trial enrollment is grossly inefficient," said Bell. "The onus is on individual patients and their doctors to identify and apply for trials. If a patient is not eligible for one trial, they must start anew looking for another."

In contrast, treating physicians who have patients participating in the clinical study at Oxford will receive a report, based on genetic analysis, outlining which of the trials ongoing at Oxford could be a suitable match for each of their patients in the program.

"We're trying to evolve a new model for both cance
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SOURCE Life Technologies Corporation
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