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Life Technologies Consortium to Create New Frontline Diagnostic Utilising DNA Sequencing for Cancer Patients in the U.K.
Date:6/22/2011

nical trials and new research insights. Meanwhile, the National Health Service (NHS) can save money through effective allocation of treatments. Market analysis indicates that even if only five per cent of cancer patients avoided one round of ineffective therapy, more than 375 million pounds Sterling (US$560) would be saved.

In addition, the programme also aims to make clinical trial enrollment less of a trial-and-error process. Today, patients learn about clinical trial opportunities through their physician or online resources. They may qualify for a trial based on a number of factors including specific genetic markers or profile.  With standardised genomic testing in place, one diagnostic test will enable a physician to recommend several trials that may be suitable for their patient. At the same time, pharma companies should be able to start their studies more quickly, and will be able to review the genetic profile of patient cohorts to better understand the genetic factors associated with favorable or unfavorable drug response. A new clinical trial model could emerge.

Demonstrating medical benefit of broad genomic sequencing, while creating an efficient new model for clinical trials

Britain's largest cancer charity, Cancer Research UK is implementing a separate but complementary programme which aims to demonstrate the benefit of routinely testing tumour samples as a standardised, cost-effective process. This program is a multi-year investment that will begin with a pilot phase testing 9,000 patients' DNA for cancer markers in nine known cancer genes.

"Research into cancer genetics has led to an understanding of what gene tests can help a doctor target the right treatment for the right patient," said James Peach, Director of Stratified Medicines at Cancer Research UK.  "Cancer Research UK recognises the huge potential for targeted treatment in the future of cancer care, but we need to ensure the NHS can deliver the tes
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SOURCE Life Technologies Corporation
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