Navigation Links
Lexicon's Drug Candidate LX1032 for Carcinoid Syndrome Receives Orphan Drug Designation From EMEA
Date:7/21/2009

s a biomarker used in the diagnosis of the condition. In preclinical studies, LX1032 reduced peripheral serotonin in several different species without affecting serotonin levels in the brain. In Phase 1 clinical studies, LX1032 reduced serotonin levels and urinary 5-HIAA in healthy volunteers consistent with preclinical results. LX1032 is being developed under Fast Track designation from the U.S. Food and Drug Administration and orphan drug designation from the European Medicines Agency.

About Carcinoid Syndrome

Carcinoid syndrome is a chronic condition caused by metastatic neuroendocrine tumors that usually originate from the gastrointestinal tract. These tumors secrete large amounts of serotonin, which can cause a variety of symptoms including severe diarrhea and abdominal discomfort. Patients with carcinoid syndrome currently have limited therapeutic options, and the standard of care includes chronic therapy with somatostatin analogues, which are delivered by injection. With current therapy, the gastrointestinal symptoms return over time in the vast majority of patients, hence the need for new agents.

About Lexicon

Lexicon is a biopharmaceutical company focused on discovering and developing breakthrough treatments for human disease. Lexicon currently has five drug candidates in development for autoimmune disease, carcinoid syndrome, diabetes, glaucoma and irritable bowel syndrome, all of which were discovered by the company's research team. The company has used its proprietary gene knockout technology to identify more than 100 promising drug targets. Lexicon has focused drug discovery efforts on these biologically-validated targets to create its extensive pipeline of clinical and preclinical programs. For additional information about Lexicon and its programs, please visit www.lexpharma.com.


'/>"/>

SOURCE Lexicon Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Cardax Pharmaceuticals Nominates Clinical Candidate Heptax for Liver Disease; Heptax Ameliorates Inflammation and Oxidative Stress Related to Liver Disease and Metabolic Syndrome
2. Cognition Therapeutics Closes Series A Financing to Advance Drug Candidates for Alzheimers Disease
3. Vantia Therapeutics Lead Candidate VA106483 Demonstrates Positive Anti-diuretic Effect in Phase IIa Trial in Nocturia
4. CeNeRx BioPharma Obtains Rights to Novel Drug Candidate for Prevention and Treatment of Neurodegeneration Disorders
5. Proteolix, Inc. Drug Candidate, PR-957, Prevents Disease Progression in Rheumatoid Arthritis Models by Selective Inhibition of the Immunoproteasome
6. Lilly Advances Second Alzheimers Disease Treatment Candidate Into Late-Stage Testing by Launching Two Global Trials
7. Arcion Therapeutics Topical Pain Candidate, ARC-4558, Significantly Reduces Pain Caused by Diabetic Neuropathy
8. Potentia Pharmaceuticals POT-4 Drug Candidate for Age-Related Macular Degeneration Successfully Completes Phase I Clinical Trial - Prepares for Phase II
9. First Candidate from Esperances Targeted Anti-cancer Platform, EP-100, Establishes Preclinical Proof of Concept
10. Optimer Pharmaceuticals Receives Production Patent for Lead Product Candidate Fidaxomicin
11. AACR Data Highlights InNexus Preclinical Antibody Candidate
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/22/2015)... , May 22, 2015  China Nepstar Chain Drugstore ... leading retail drugstore chain in China ... today announced the resignation of Mr. Fuxiang Zhang ... reasons, effective immediately. Ms. Rebecca Yingnan Zhang ... Company,s board of directors, effective immediately. Meanwhile, Ms. Zhang ...
(Date:5/21/2015)... Research and Markets ... of the "Arthroscopy Devices Markets Worldwide" ... http://photos.prnewswire.com/prnh/20130307/600769) , ,The purpose of this report ... market for Arthroscopy Devices. The report discusses ... market for these products. , ,Product - ...
(Date:5/21/2015)... , 21. Mai 2015 /PRNewswire/ ... DPRX ), ein Unternehmen für Arzneimittel ... die Entwicklung und Vermarktung von Locilex® ... kündigte heute eine wissenschaftliche Posterpräsentation an, ... des Unternehmens vorstellt, OneStep-1 und OneStep-2, ...
Breaking Medicine Technology:China Nepstar Chain Drugstore Ltd. Announces Management Change and New Director Appointment 2China Nepstar Chain Drugstore Ltd. Announces Management Change and New Director Appointment 3Analysing Arthroscopy Devices Markets Worldwide 2014-2020 2Analysing Arthroscopy Devices Markets Worldwide 2014-2020 3Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 2Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 3Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 4Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 5Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 6Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 7
... THE OHIO STATE UNIVERSITY ... CENTER JOINS PHASE III TRIAL FOR METASTATIC MELANOMA ... (Nasdaq: DCTH ) announced today that The Ohio ... Research Institute has joined Delcath,s Phase III clinical trial for the treatment ...
... online this week in the Journal of Clinical ... selective estrogen receptor modulator (SERM) being developed by Eli ... increased lumbar spine and total hip bone mineral density ... mass, versus placebo.In addition, arzoxifene, dosed at 20 mg/day, ...
Cached Medicine Technology:Delcath Continues Expansion of Clinical Trial Centers Offering PHP(TM) 2Delcath Continues Expansion of Clinical Trial Centers Offering PHP(TM) 3Newly Published Phase III Study Shows Arzoxifene Significantly Increased Bone Mineral Density 2Newly Published Phase III Study Shows Arzoxifene Significantly Increased Bone Mineral Density 3Newly Published Phase III Study Shows Arzoxifene Significantly Increased Bone Mineral Density 4
(Date:5/22/2015)... 22, 2015 Pioneer Millworks, the largest ... forefront of designing with reclaimed wood, introducing their latest ... Angeles, California. Their newest offerings, Vat 35, Reclaimed ... and color to America's largest design event. , “Designers, ... each show, anxious to see and feel the variety ...
(Date:5/22/2015)... 2015 River Valley Health Partners (RVHP) ... health system’s Chief Financial Officer (CFO), will be leaving ... as the company CFO since 2011. , The Board ... the health system as CFO. Wesley will oversee the ... the Board of Trustees conducts a formal search for ...
(Date:5/22/2015)... Pa. (PRWEB) May 22, 2015 Omar ... been selected to participate in the 2015 Congress of ... is described as a gathering of “America’s highest achieving ... new areas of healthcare, set new goals and learn ... include a live surgery, during which we can ask ...
(Date:5/22/2015)... “It’s like learning an new ... Vice President of Clinical Operations/Education and Training at ... impacts how care is coded and reimbursed.” , ... care reimbursement, operations and compliance consulting, as well ... launches a new series of day-long seminars on ...
(Date:5/22/2015)... May 22, 2015 Coordinating care ... difficult process. Historically providers have not been reimbursed ... Starting in 2015, Medicare has paved the way ... Thanks to the launch of Oculus Health ... health systems using the platform will now be ...
Breaking Medicine News(10 mins):Health News:Pioneer Millworks to Reveal New Design Trends with Reclaimed Wood at Dwell on Design in LA 2Health News:Pioneer Millworks to Reveal New Design Trends with Reclaimed Wood at Dwell on Design in LA 3Health News:River Valley Health Partners Announces CFO Transition, Appointment of Interim CFO 2Health News:Milton Hershey School Student Chosen for Congress of Future Medical Leaders 2Health News:Harmony Healthcare International Takes the Lead in Launching ICD-10 Coding Transition in Post-Acute Care 2Health News:Harmony Healthcare International Takes the Lead in Launching ICD-10 Coding Transition in Post-Acute Care 3Health News:Oculus Health Care Coordination Platform Officially Launched 2Health News:Oculus Health Care Coordination Platform Officially Launched 3Health News:Oculus Health Care Coordination Platform Officially Launched 4
... (NYSE: LNC ) today announced the introduction of ... disability (LTD) insurance product. Lincoln already offers one of the ... the addition of this optional benefit -- employers now have ... cost concerns as they try to return to work. (Logo: ...
... bacteria that threaten those with COPD, study says , , ... smoking help cause chronic obstructive pulmonary disease (COPD), it ... can worsen the disease, Canadian researchers report. , The ... how smokers with COPD are treated, the experts said. ...
... ETS EXPOSURE , Environmental tobacco smoke (ETS) exposure ... However, a new study shows that reducing exposure ... Alabama researchers followed 240 children with asthma who ... therapy. No smoking cessation counseling or ETS exposure ...
... RAC Credential Focuses on General Scope of Regulatory ... The Regulatory Affairs Professionals Society (RAPS) has ... RAC General Scope (GS). The RAC (GS) credential ... practice of regulatory professionals in the healthcare product ...
... DETROIT, April 7 The Detroit Wayne County ... enrollment service that will expedite the screening and ... called HelpEngen(TM), was developed by TriHealix, a health ... enables health care providers to connect uninsured patients ...
... http://www.HealthGuru.com ) was the fastest growing health site on the web over ... of the few health sites with more video views than unique visitors ... ... 7, 2009 -- According to the comScore, Inc. February rankings, Health Guru ...
Cached Medicine News:Health News:Lincoln Financial Group Announces Family Care Reimbursement Benefit Rider on LTD Policies 2Health News:Lincoln Financial Group Announces Family Care Reimbursement Benefit Rider on LTD Policies 3Health News:Lincoln Financial Group Announces Family Care Reimbursement Benefit Rider on LTD Policies 4Health News:Smoking Ups Infection Risk for Lung Disease Patients 2Health News:Journal Chest: April news briefs 2Health News:RAPS Offers New International Regulatory Affairs Certification - RAC (GS) 2Health News:Health Authority Offers Expedient, Web-Based Medicaid Enrollment Service 2Health News:Health Authority Offers Expedient, Web-Based Medicaid Enrollment Service 3Health News:Web's Fastest Growing Health Site is a Video Site 2Health News:Web's Fastest Growing Health Site is a Video Site 3
... pulsed radiofrequncy current, the Valleylab ... heats and ablates large volumes ... minimal time., RF alblation procedures ... surgery, percutaneously, or laparoscopically, depending ...
... is a biologically based adhesive supplied ... system consisting of a liquid substrate ... of internal bleeding. When ... on to a prepared wound and ...
... (Human) achieves a secure clot, targeted to ... for hemostasis is needed, when control of ... ligature, and cautery, is ineffective or impractical., ... formulation of human Biologically Active Component (BAC) ...
... BD Cell-Tak™ Cell and Tissue Adhesive ... from Mytilus edulis (marine mussel). These proteins ... secreted by the mussel to anchor itself ... BD Cell-Tak Cell and Tissue Adhesive is ...
Medicine Products: