Navigation Links
Lexicon's Drug Candidate LX1032 for Carcinoid Syndrome Receives Orphan Drug Designation From EMEA
Date:7/21/2009

s a biomarker used in the diagnosis of the condition. In preclinical studies, LX1032 reduced peripheral serotonin in several different species without affecting serotonin levels in the brain. In Phase 1 clinical studies, LX1032 reduced serotonin levels and urinary 5-HIAA in healthy volunteers consistent with preclinical results. LX1032 is being developed under Fast Track designation from the U.S. Food and Drug Administration and orphan drug designation from the European Medicines Agency.

About Carcinoid Syndrome

Carcinoid syndrome is a chronic condition caused by metastatic neuroendocrine tumors that usually originate from the gastrointestinal tract. These tumors secrete large amounts of serotonin, which can cause a variety of symptoms including severe diarrhea and abdominal discomfort. Patients with carcinoid syndrome currently have limited therapeutic options, and the standard of care includes chronic therapy with somatostatin analogues, which are delivered by injection. With current therapy, the gastrointestinal symptoms return over time in the vast majority of patients, hence the need for new agents.

About Lexicon

Lexicon is a biopharmaceutical company focused on discovering and developing breakthrough treatments for human disease. Lexicon currently has five drug candidates in development for autoimmune disease, carcinoid syndrome, diabetes, glaucoma and irritable bowel syndrome, all of which were discovered by the company's research team. The company has used its proprietary gene knockout technology to identify more than 100 promising drug targets. Lexicon has focused drug discovery efforts on these biologically-validated targets to create its extensive pipeline of clinical and preclinical programs. For additional information about Lexicon and its programs, please visit www.lexpharma.com.


'/>"/>

SOURCE Lexicon Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Cardax Pharmaceuticals Nominates Clinical Candidate Heptax for Liver Disease; Heptax Ameliorates Inflammation and Oxidative Stress Related to Liver Disease and Metabolic Syndrome
2. Cognition Therapeutics Closes Series A Financing to Advance Drug Candidates for Alzheimers Disease
3. Vantia Therapeutics Lead Candidate VA106483 Demonstrates Positive Anti-diuretic Effect in Phase IIa Trial in Nocturia
4. CeNeRx BioPharma Obtains Rights to Novel Drug Candidate for Prevention and Treatment of Neurodegeneration Disorders
5. Proteolix, Inc. Drug Candidate, PR-957, Prevents Disease Progression in Rheumatoid Arthritis Models by Selective Inhibition of the Immunoproteasome
6. Lilly Advances Second Alzheimers Disease Treatment Candidate Into Late-Stage Testing by Launching Two Global Trials
7. Arcion Therapeutics Topical Pain Candidate, ARC-4558, Significantly Reduces Pain Caused by Diabetic Neuropathy
8. Potentia Pharmaceuticals POT-4 Drug Candidate for Age-Related Macular Degeneration Successfully Completes Phase I Clinical Trial - Prepares for Phase II
9. First Candidate from Esperances Targeted Anti-cancer Platform, EP-100, Establishes Preclinical Proof of Concept
10. Optimer Pharmaceuticals Receives Production Patent for Lead Product Candidate Fidaxomicin
11. AACR Data Highlights InNexus Preclinical Antibody Candidate
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... The American Association for Homecare (AAHomecare) is ... has joined the AAHomecare Corporate Partner Program. ... have been actively involved in AAHomecare for much of ... grown into a major global manufacturer of home medical ... to increase efforts on behalf of the HME sector ...
(Date:9/19/2014)... 2014 Larry J. Merlo , President and ... speak before the National Press Club in Washington, ... move to stop selling tobacco products and its leadership in ... "Dramatic changes in our health care system pose ... Merlo has said. "CVS Health has a truly unique combination ...
(Date:9/19/2014)...  Lpath, Inc. (NASDAQ: LPTN ), ... today that it has entered into definitive agreements ... and 3,605,042 unregistered warrants in a registered direct ... share of common stock and one unregistered warrant ... will be $3.475.  The warrants have an exercise ...
Breaking Medicine Technology:Drive Medical Design & Manufacturing Joins AAHomecare Corporate Partner Program 2CVS Health CEO to Address National Press Club on Landmark Decision to Quit Tobacco, Leadership in Health Care Innovation 2CVS Health CEO to Address National Press Club on Landmark Decision to Quit Tobacco, Leadership in Health Care Innovation 3Lpath, Inc. Announces $12.5 Million Registered Direct Offering 2Lpath, Inc. Announces $12.5 Million Registered Direct Offering 3
... , BEDFORD, Ohio , Jan. 14 ... is pleased to announce FDA approval for the addition of ... line. This product is AP rated and is equivalent to ... for oropharyngeal and esophageal candidiasis, cryptococcal meningitis, and is indicated ...
... , , BETHLEHEM, Pa. , Jan. 13 ... and easy-to-use WHIN ® Safe Huber Needle , an implantable ... a single Huber Needle and provides clinicians with advanced protection ... http://www.newscom.com/cgi-bin/prnh/20081022/NYW008LOGO ) , There are three models of the WHIN ® ...
Cached Medicine Technology:Bedford Laboratories(TM) To Begin Shipping Fluconazole Injection 2Bedford Laboratories(TM) To Begin Shipping Fluconazole Injection 3Bedford Laboratories(TM) To Begin Shipping Fluconazole Injection 4B. Braun Introduces WHIN(R) Safe Huber Needle 2B. Braun Introduces WHIN(R) Safe Huber Needle 3B. Braun Introduces WHIN(R) Safe Huber Needle 4
(Date:9/20/2014)... Ticket Down is a dependable source for ... ticket exchange is offering their customer appreciation promo code ARIANA-2015 ... tours is beginning to fill up. Many of the biggest ... the road, including 21-year-old pop superstar, Ariana Grande. Grande, a ... will take her to 25 cities across the United States ...
(Date:9/20/2014)... York, New York (PRWEB) September 20, 2014 ... filings continue to grow in federal court, Bernstein ... Food & Drug Administration (FDA) have voted overwhelmingly ... low testosterone in men be subjected to further ... According to a report published on September 18th ...
(Date:9/20/2014)... avian flu that killed 160 harbor seals in New ... and therefore poses a potential threat to humans, according ... have been linked to the harbor seal virus, researchers ... mutations to the avian H3N8 seal virus that might ... Current seasonal flu vaccines wouldn,t help in such ...
(Date:9/20/2014)... September 20, 2014 Ticket Down ... concert tickets for her 2015 “Honeymoon Tour.” This well-known ... for added savings. , In early 2015, fans will have ... the world across North America. Twenty-one-year-old Ariana Grande will hit ... will take her to 25 cities across the United States ...
(Date:9/20/2014)... September 20, 2014 iFitDress.com, the popular ... for women, has recently unveiled its new collection of ... sale for special offer on these new outfits; it ... season. All customers can now buy cheap cocktail ... company’s sales representative says, “We have extensive experience in ...
Breaking Medicine News(10 mins):Health News:Ariana Grande Tickets in Phoenix, Los Angeles, Anaheim, San Jose, Seattle, and Vancouver Go on Sale Today 2Health News:Ariana Grande Tickets in Phoenix, Los Angeles, Anaheim, San Jose, Seattle, and Vancouver Go on Sale Today 3Health News:As Testosterone Lawsuits Grow, Bernstein Liebhard LLP Notes Overwhelming Vote Calling for Further Study of Testosterone Heart Risks 2Health News:As Testosterone Lawsuits Grow, Bernstein Liebhard LLP Notes Overwhelming Vote Calling for Further Study of Testosterone Heart Risks 3Health News:Avian Flu In Harbor Seals Could Infect People 2Health News:Ariana Grande Tickets in New York, Philadelphia, Orlando, Fairfax, Worcester, Toronto, Uncasville, Detroit, Miami, Pittsburgh, Cleveland, and Atlanta On Sale Today 2Health News:Ariana Grande Tickets in New York, Philadelphia, Orlando, Fairfax, Worcester, Toronto, Uncasville, Detroit, Miami, Pittsburgh, Cleveland, and Atlanta On Sale Today 3Health News:Fashionable Cocktail Dresses Unveiled Online at iFitDress.com 2
... TOWN, South Africa, March 11 The medical ... as Kenya, Tanzania, Ghana, Zambia, and Malawi is ... however, an increasing level of awareness of the ... the public.(Logo: http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO )"This is further ...
... and Businesses Nationwide Team Up To Support ,The Project--The Children,s Rare ... ... 11, 2009 -- Children, businesses, schools and organizations from states all ... on February 28, 2009, for World Rare Disease Day to call ...
... Group LTD ("KineMatik"), providers of software solutions for managing scientific ... Jose King-Shaw Jr. will join its Board of Directors. ... ... 2009 -- The KineMatikTM Group LTD ("KineMatik"), providers ...
... Previous conference SOLD OUT in less than 72 hours.,* Health insurance ... Sales Development and Online Marketing Strategies , ... Chicago, ... insurance agent training conference to Dallas, Texas, on Thursday, March 26, ...
... laser procedure on The Doctors national show, Tuesday, March ... Calif., March 10 Lumenis Ltd., a global developer, ... for surgical, aesthetic, and ophthalmic applications, announced that its ... national television show on Tuesday, March 10, 2009 as ...
... as indicator of other problems, expert says , , TUESDAY, March ... are 15 times more likely than other women to suffer ... and three times more likely to have blood clots and ... , "Good prenatal care is essential. Women with persistent and ...
Cached Medicine News:Health News:Medical Insurance Coverage in Africa a Possible Key to Improved Healthcare Access, States Frost & Sullivan 2Health News:Medical Insurance Coverage in Africa a Possible Key to Improved Healthcare Access, States Frost & Sullivan 3Health News:Patient Advocacy Teams Help Turn World Rare Disease Day 2009 Into A Global Success 2Health News:Patient Advocacy Teams Help Turn World Rare Disease Day 2009 Into A Global Success 3Health News:Mr. Ruben Jose King-Shaw Jr. to Join KineMatik Board of Directors 2Health News:Mr. Ruben Jose King-Shaw Jr. to Join KineMatik Board of Directors 3Health News:Dallas To Host Intensive Norvax University Insurance Agent Sales Training and Web Marketing Conference on March 26 2Health News:Dallas To Host Intensive Norvax University Insurance Agent Sales Training and Web Marketing Conference on March 26 3Health News:Dallas To Host Intensive Norvax University Insurance Agent Sales Training and Web Marketing Conference on March 26 4Health News:Lumenis(R) UltraPulse CO2 Laser to be Featured on National Television with Live Pearly Penile Papule (PPP) Procedure 2Health News:Migraines in Pregnancy Boost Vascular Risks 2
... broad selection of tip styles for ... ophthalmic procedures. Each single use cautery ... safety cap to lock switch in ... in use, and carries a 3-4 ...
... a broad selection of tip styles ... of ophthalmic procedures. Each single use ... a safety cap to lock switch ... not in use, and carries a ...
... Accu-Temp Cauteries provide a broad selection ... a wide variety of ophthalmic procedures. ... sterile, complete with a safety cap ... " position when not in use, ...
... The B-VAT® PC visual acuity system ... features of the B-VAT II. The system ... sequencing, contrast sensitivity testing and animated characters. ... the operator has single letter, single line ...
Medicine Products: